Our mechanistic research includes efforts to understand:
- Barriers in solid organ transplantation
- Fundamental mechanisms of apoptosis
- Events in several major cancer signaling pathways
- Cellular immune biomarkers predictive of human disease outcomes
- Host-pathogen interactions in HIV
Novel therapeutics under development include:
- Tumor-targeting reagents
- Novel vaccines to fight cancer and viral infections
Research Programs
Several laboratories in the division investigate questions in cancer genetics and cancer biology.
Applied Therapeutics
Identifying, quantifying and eliminating local disease while preserving and optimizing functional recovery
Devi Research Lab
Studying basic and fundamental mechanisms of apoptosis, or programmed cell death
Nair Research Lab
Designing and testing novel vaccines against cancer and viral infections in murine and human systems
Cardiovascular Biology Laboratory
Developing novel, safe, and effective nucleic acid therapeutics
Individual Faculty
The following faculty members also conduct research in cancer genetics and biology:
The immunology program is centered on dendritic cell antigen presentation platforms and an extensive repertoire of immune monitoring technologies to support the development and clinical testing of novel immune-based therapies.
Laboratory for AIDS Vaccine Research and Development
Identifies immunogens that generate broadly cross-reactive neutralizing antibodies against HIV-1 for inclusion in vaccines
Nair Research Lab
Designs and tests novel vaccines against cancer and viral infections in murine and human systems
Immune Responses and Virology
Works to understand host-pathogen interactions in HIV
Immunologic Signatures Laboratory
Develops innovative immune therapeutic approaches that apply to patients with HIV, emerging infections, and solid tumors
Individual Faculty
The following faculty members also conduct immunology research:
Our researchers apply these state-of-the-art technologies to the development of novel therapeutic strategies for cancer and autoimmune and infectious diseases.
Devi Research Lab
Studying basic and fundamental mechanisms of apoptosis, or programmed cell death
Cardiovascular Biology Laboratory
Developing novel, safe, and effective nucleic acid therapeutics
Individual Faculty