Research Laboratories

Cardiothoracic Surgery Translational Research Laboratory

The Cardiothoracic Surgery Translational Research Laboratory investigates a number of questions relevant to cardiac surgery, heart failure, cardiac transplantation, and mechanical circulatory support. Translational research is conducted utilizing clinical specimens obtained through the Duke Human Heart Repository and large and small animal models. 

Duke Center for Aortic Disease Research Program

Our goal is to further our understanding of the pathophysiology of aortic diseases, develop better surgical and non-surgical treatments, and improve short- and long-term outcomes after thoracic aortic surgery.

Mechanical Support for Heart and Lung Disease Research

Duke researchers, including Jacob Klapper, MD, and Benjamin Bryner, MD, are investigating the use of mechanical circulatory support for individuals with acute treatable conditions causing lung or heart failure.