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Research Laboratories

The Cardiothoracic Surgery Translational Research Laboratory investigates a number of questions relevant to cardiac surgery, heart failure, cardiac transplantation, and mechanical circulatory support. Translational research is conducted utilizing clinical specimens obtained through the Duke Human Heart Repository and large and small animal models. The lab has expertise and experience with...
To further our understanding of the pathophysiology of aortic diseases, develop better surgical and non-surgical treatments, and improve short- and long-term outcomes after thoracic aortic surgery.
Duke researchers, including Jacob Klapper, MD, and Benjamin Bryner, MD, are investigating the use of mechanical circulatory support for individuals with acute treatable conditions causing lung or heart failure. Duke has developed multiple research programs in physiology, immunology, vascular biology, hematology, cellular and molecular biology, focusing on the effect of mechanical circulatory...