The Section of Hepatopancreatobiliary (HPB) Surgery is dedicated to pioneering new treatments for pancreas, liver, sarcoma, and peritoneal cancer through basic and clinical research.
Our Surgical Oncology Research Group meets regularly to discuss the latest areas of investigation in the field, and we present frequently at national meetings.
Through ongoing research and clinical trials, we aim to improve outcomes. As part of the National Comprehensive Cancer Network, we belong to an alliance of the country’s top cancer centers committed to improving patient care, research, and education.
Recent research projects include:
- Pancreatic cancer registry: Optimizing efficacy of multimodality therapies for pancreatic cancer
- Immune system’s response in pancreatic cancer
- Role of surgery in metastatic pancreatic cancer
- Enhanced recovery with minimally invasive surgery after pancreaticoduodenectomy (Whipple)
- Liver registry
Discovery of novel therapeutic strategies for cholangiocarcinoma: We apply high throughput, unbiased techniques to study functional genomics and molecular signaling pathways in cholangiocarcinoma, so as to identify tumor-specific dependencies, novel therapeutic agents, and/or targetable pathways, ultimately translating into clinical trials and improved patient outcomes.
Our faculty are active in clinical trials to improve HPB treatments. These include:
- Negative Pressure Wound Therapy in Reducing Postoperative Surgical Site Infections in Patients Undergoing Surgery of the Colon, Rectum, Liver, Pancreas, or Gallbladder
- Proton or Photon RT for Retroperitoneal Sarcomas
- Percutaneous Hepatic Perfusion vs Best Alternative Care in Patients With Hepatic-dominant Ocular Melanoma (FOCUS)
- The Prevention of Progression to Pancreatic Cancer Trial (The 3P-C Trial)
- Trial using hepatic arterial infusion chemotherapy for locally advanced intrahepatic cholangocarcinoma (one of five participating sites in the world)
Identification of cyst fluid biomarkers to determine high risk IPMN
PLANET Trial: Precision Medicine in Liver Cancer across an Asia-Pacific Network: A Multi-National Cohort Study on the Impact of Intra-Tumoural Heterogeneity and Immune Micro-Environment on the Clinical Trajectory of Resected Hepatocellular Carcinoma — This study aims to investigate the genomic heterogeneity and immunological profile of surgically resected HCC, and relate them to the subsequent clinical trajectory.
Dr. Allen's Recent Publications
Dr. Blazer's Recent Publications
Dr. Herbert's Recent Publications
Dr. Lidsky's Recent Publications
Dr. Pappas's Recent Publications
Dr. Shah's Recent Publications
Dr. Zani's Recent Publications