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Paul Joseph Mosca, MD, PhD, MBA

Associate Professor of Surgery
Division: 
Surgical Oncology
Section: 
Melanoma Surgery
Program: 
General Surgery Residency Program
Office: 10 Bryan Searle Drive, 466G Seeley G. Mudd Bldg, Durham, NC 27710
Campus Mail: DUMC 3966, 10 Bryan Searle Dr, 466G Seeley G Mudd, Durham, NC 27710

My research focuses on three areas. One is the development of more effective and entirely novel treatments for melanoma. I have a special interest in immunotherapy, novel targeted molecular therapies, and regional chemotherapy for advanced melanoma of the arm or leg. Another area of interest is palliative surgery for cancer with an emphasis on understanding the optimal role and application of this type of surgery in the care of advanced malignancy. A third area of interest is quality and patient safety with an emphasis on communication and work culture.

Education and Training

  • Assistant Professor, Surgery, Lehigh Valley Health Network, 2004 - 2010
  • Assistant Professor, Surgery, Duke University School of Medicine, 2002 - 2004
  • Chief Resident, Surgery, Duke University, 2001 - 2002
  • 2nd Year SAR, Surgery, Duke University, 2000 - 2001
  • Surgical Research Fellow, Surgery, Duke University, 1998 - 2000
  • Senior Assistant Resident, Surgery, Duke University, 1997 - 1998
  • Junior Assistant Resident, Surgery, Duke University, 1996 - 1997
  • Intern, Surgery, Duke University, 1995 - 1996
  • M.B.A., Desales University, 2011
  • M.D., University of Virginia, 1995
  • Ph.D., University of Virginia, 1994

Selected Grants

Publications

Puza, CJ, Myers, SA, Cardones, AR, Beasley, GM, and Mosca, PJ. "The impact of transplant rejection on cutaneous squamous cell carcinoma in renal transplant recipients." Clinical and Experimental Dermatology 44, no. 3 (April 2019): 265-269.

Full Text

Miura, JT, Kroon, HM, Beasley, GM, Mullen, D, Farrow, NE, Mosca, PJ, Lowe, MC, Farley, CR, Kim, Y, Naqvi, SMH, Potdar, A, Daou, H, Sun, J, Farma, JM, Henderson, MA, Speakman, D, Serpell, J, Delman, KA, Mark Smithers, B, Coventry, BJ, Tyler, DS, Thompson, JF, and Zager, JS. "Long-Term Oncologic Outcomes After Isolated Limb Infusion for Locoregionally Metastatic Melanoma: An International Multicenter Analysis." March 25, 2019.

Full Text

Puza, CJ, Mosca, PJ, and Cardones, AR. "Early-stage melanoma and hematopoietic stem cell transplantation outcomes." Journal of the American Academy of Dermatology 80, no. 3 (March 2019): 786-788. (Letter)

Full Text

Masoud, SJ, Hu, JB, Beasley, G, Stewart, JH, and Mosca, PJ. "Efficacy of Talimogene Laherparepvec (T-VEC) Therapy in Patients with In-Transit Melanoma Metastasis Decreases with Increasing Lesion Size." 72nd Annual Cancer Symposium of the Society-of-Surgical-Oncology (SSO). San Diego, CA. March 27, 2019 - March 30, 2019.: SPRINGER, February 1, 2019.

Scholars@Duke

Kwak, M, Farrow, NE, Salama, AKS, Mosca, PJ, Hanks, BA, Slingluff, CL, and Beasley, GM. "Updates in adjuvant systemic therapy for melanoma." Journal of Surgical Oncology 119, no. 2 (January 2019): 222-231. (Review)

Full Text

Adair, KC, Quow, K, Frankel, A, Mosca, PJ, Profit, J, Hadley, A, Leonard, M, and Bryan Sexton, J. "The Improvement Readiness scale of the SCORE survey: a metric to assess capacity for quality improvement in healthcare." Bmc Health Services Research 18, no. 1 (December 17, 2018): 975-null.

Full Text

Puza, CJ, Barbas, AS, and Mosca, PJ. "Outcomes of patients with a pretransplant history of early-stage melanoma." Melanoma Research 28, no. 5 (October 2018): 471-474.

Full Text

Masoud, SJ, Perone, JA, Farrow, NE, Mosca, PJ, Tyler, DS, and Beasley, GM. "Sentinel Lymph Node Biopsy and Completion Lymph Node Dissection for Melanoma." Current Treatment Options in Oncology 19, no. 11 (September 19, 2018): 55-null. (Review)

Full Text

Puza, CJ, and Mosca, PJ. "Examining the incidence and presentation of melanoma in thoracic transplant patients." Annual Meeting of the American-Academy-of-Dermatology (AAD). San Diego, CA. February 16, 2018 - February 20, 2018.: MOSBY-ELSEVIER, September 1, 2018.

Scholars@Duke

Puza, CJ, and Mosca, PJ. "Examining the incidence and presentation of melanoma in thoracic transplant patients." Annual Meeting of the American-Academy-of-Dermatology (AAD). San Diego, CA. February 16, 2018 - February 20, 2018.: MOSBY-ELSEVIER, September 1, 2018.

Scholars@Duke

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