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Paul Joseph Mosca, MD, PhD, MBA

Associate Professor of Surgery
Division: 
Surgical Oncology
Section: 
Melanoma Surgery
Program: 
Complex General Surgical Oncology Fellowship
Duke Surgical Technique and Review (STAR) Course
General Surgery Residency Program
Office: 10 Bryan Searle Drive, 466G Seeley G. Mudd Bldg, Durham, NC 27710
Campus Mail: DUMC 3966, 10 Bryan Searle Dr, 466G Seeley G Mudd, Durham, NC 27710

My research focuses on three areas. One is the development of more effective and entirely novel treatments for melanoma. I have a special interest in immunotherapy, novel targeted molecular therapies, and regional chemotherapy for advanced melanoma of the arm or leg. Another area of interest is palliative surgery for cancer with an emphasis on understanding the optimal role and application of this type of surgery in the care of advanced malignancy. A third area of interest is quality and patient safety with an emphasis on communication and work culture.

Education and Training

  • Assistant Professor, Surgery, Lehigh Valley Health Network, 2004 - 2010
  • Assistant Professor, Surgery, Duke University School of Medicine, 2002 - 2004
  • Chief Resident, Surgery, Duke University, 2001 - 2002
  • 2nd Year SAR, Surgery, Duke University, 2000 - 2001
  • Surgical Research Fellow, Surgery, Duke University, 1998 - 2000
  • Senior Assistant Resident, Surgery, Duke University, 1997 - 1998
  • Junior Assistant Resident, Surgery, Duke University, 1996 - 1997
  • Intern, Surgery, Duke University, 1995 - 1996
  • M.B.A., Desales University, 2011
  • M.D., University of Virginia, 1995
  • Ph.D., University of Virginia, 1994

Selected Grants

Publications

Nobuhara, Chloe K., W Michael Bullock, Thomas Bunning, Brian Colin, Mary Cooter, Michael J. Devinney, Michael N. Ferrandino, et al. “A protocol to reduce self-reported pain scores and adverse events following lumbar punctures in older adults.” J Neurol 267, no. 7 (July 2020): 2002–6. https://doi.org/10.1007/s00415-020-09797-1.

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Teras, Jüri, Hidde M. Kroon, John T. Miura, Tim Kenyon-Smith, Georgia M. Beasley, Dean Mullen, Norma E. Farrow, et al. “International Multicenter Experience of Isolated Limb Infusion for In-Transit Melanoma Metastases in Octogenarian and Nonagenarian Patients.” Ann Surg Oncol 27, no. 5 (May 2020): 1420–29. https://doi.org/10.1245/s10434-020-08312-0.

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Puza, Charles J., Georgia M. Beasley, Andrew S. Barbas, and Paul J. Mosca. “Type of Organ Transplanted Impacts the Risk and Presentation of Cutaneous Squamous Cell Carcinoma in Transplant Recipients.” Exp Clin Transplant 18, no. 1 (February 2020): 93–97. https://doi.org/10.6002/ect.2018.0238.

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Masoud, Sabran J., Janice B. Hu, Georgia M. Beasley, John H. Stewart, and Paul J. Mosca. “Efficacy of Talimogene Laherparepvec (T-VEC) Therapy in Patients with In-Transit Melanoma Metastasis Decreases with Increasing Lesion Size.” In Ann Surg Oncol, 26:4633–41, 2019. https://doi.org/10.1245/s10434-019-07691-3.

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Masoud, Sabran J., Jennifer A. Perone, Norma E. Farrow, Paul J. Mosca, Douglas S. Tyler, and Georgia M. Beasley. “Correction to: Sentinel Lymph Node Biopsy and Completion Lymph Node Dissection for Melanoma.” Curr Treat Options Oncol 20, no. 10 (August 29, 2019): 76. https://doi.org/10.1007/s11864-019-0674-x.

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Miura, John T., Hidde M. Kroon, Georgia M. Beasley, Dean Mullen, Norma E. Farrow, Paul J. Mosca, Michael C. Lowe, et al. “Long-Term Oncologic Outcomes After Isolated Limb Infusion for Locoregionally Metastatic Melanoma: An International Multicenter Analysis.” In Ann Surg Oncol, 26:2486–94, 2019. https://doi.org/10.1245/s10434-019-07288-w.

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Puza, C. J., S. A. Myers, A. R. Cardones, G. M. Beasley, and P. J. Mosca. “The impact of transplant rejection on cutaneous squamous cell carcinoma in renal transplant recipients.” Clin Exp Dermatol 44, no. 3 (April 2019): 265–69. https://doi.org/10.1111/ced.13699.

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Kwak, Minyoung, Norma E. Farrow, April K. S. Salama, Paul J. Mosca, Brent A. Hanks, Craig L. Slingluff, and Georgia M. Beasley. “Updates in adjuvant systemic therapy for melanoma.” J Surg Oncol 119, no. 2 (January 2019): 222–31. https://doi.org/10.1002/jso.25298.

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Adair, Kathryn C., Krystina Quow, Allan Frankel, Paul J. Mosca, Jochen Profit, Allison Hadley, Michael Leonard, and J. Bryan Sexton. “The Improvement Readiness scale of the SCORE survey: a metric to assess capacity for quality improvement in healthcare.” Bmc Health Serv Res 18, no. 1 (December 17, 2018): 975. https://doi.org/10.1186/s12913-018-3743-0.

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