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Herbert Kim Lyerly, MD

George Barth Geller Distinguished Professor of Immunology
Professor of Surgery
Professor in Immunology
Professor of Pathology
Office: 203 Research Drive, Rm 433B, Box 2606, Durham, NC 27710
Campus Mail: DUMC Box 2606 Med Ctr, Durham, NC 27710

Education and Training

  • M.D., University of California - Los Angeles, 1983

Selected Grants


Song, Qing-Kun, Jun Ren, Xin-Na Zhou, Xiao-Li Wang, Guo-Hong Song, Li-Jun Di, Jing Yu, et al. “The prognostic value of peripheral CD4+CD25+ T lymphocytes among early stage and triple negative breast cancer patients receiving dendritic cells-cytokine induced killer cells infusion.” Oncotarget 6, no. 38 (December 1, 2015): 41350–59.

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Song, Qingkun, Xinna Zhou, Jing Yu, Ningning Dong, Xiaoli Wang, Huabing Yang, Jun Ren, and H Kim Lyerly. “The prognostic values of CYP2B6 genetic polymorphisms and metastatic sites for advanced breast cancer patients treated with docetaxel and thiotepa.” Sci Rep 5 (November 25, 2015): 16775.

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Zhou, Xinna, Xiaoli Wang, Qingkun Song, Huabing Yang, Xishan Zhu, Jing Yu, Guohong Song, et al. “Transformation of alkylating regimen of thiotepa into tepa determines the disease progression through GSTP1 gene polymorphism for metastatic breast cancer patients receiving thiotepa containing salvage chemotherapy.” Int J Clin Pharmacol Ther 53, no. 11 (November 2015): 914–22.

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Vaidyanathan, G., D. McDougald, J. Choi, E. Koumarianou, M. Pruszynski, T. Osada, H. Lyerly, T. Lahoutte, and M. R. Zalutsky. “An Anti-HER2 Nanobody Labeled with 18F Using a Residualizing Label for Assessing HER2 Status.” In European Journal of Nuclear Medicine and Molecular Imaging, 42:S102–S102. SPRINGER, 2015.


Mook, Robert A., Jiangbo Wang, Xiu-Rong Ren, Minyong Chen, Ivan Spasojevic, Larry S. Barak, H Kim Lyerly, and Wei Chen. “Structure-activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure.” Bioorg Med Chem 23, no. 17 (September 1, 2015): 5829–38.

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Price, Trevor T., Clara H. Lee, Qing Cheng, H Kim Lyerly, William E. Fogler, John L. Magnani, and Dorothy A. Sipkins. “Abstract 3212: Metastatic breast cancer cell communication within a pro-dormancy bone marrow niche.” In Tumor Biology. American Association for Cancer Research, 2015.

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Song, Qing-Kun, Xiao-Li Wang, Xin-Na Zhou, Hua-Bing Yang, Yu-Chen Li, Jiang-Ping Wu, Jun Ren, and Herbert Kim Lyerly. “Breast Cancer Challenges and Screening in China: Lessons From Current Registry Data and Population Screening Studies.” Oncologist 20, no. 7 (July 2015): 773–79.

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Goodson, William H., Leroy Lowe, David O. Carpenter, Michael Gilbertson, Abdul Manaf Ali, Adela Lopez de Cerain Salsamendi, Ahmed Lasfar, et al. “Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.” Carcinogenesis 36 Suppl 1 (June 2015): S254–96.

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