Skip to main content

Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants

Publications

Beus, JM, Hashmi, SS, Selvaraj, SA, Duan, D, Stempora, LL, Monday, SA, Cheeseman, JA, Hamby, KM, Speck, SH, Larsen, CP, Kirk, AD, and Kean, LS. "Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection." Plos One 8, no. 8 (January 2013): e71221-null.

Full Text

Anderson, DJ, and Kirk, AD. "Primate models in organ transplantation." Cold Spring Harbor perspectives in medicine 3, no. 9 (2013): a015503-.

Full Text

Kirk, AD. "The cam-path forward." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 13, no. 1 (January 2013): 9-10.

Full Text

Velazquez, VM, Hon, H, Ibegbu, C, Knechtle, SJ, Kirk, AD, and Grakoui, A. "Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection." Hepatology (Baltimore, Md.) 56, no. 6 (December 2012): 2071-2081.

Full Text

Bruno, DA, Dhanireddy, KK, and Kirk, AD. "Liver and pancreas transplantation immunobiology." In Blumgart's Surgery of the Liver, Biliary Tract, and Pancreas, 1652-1661. December 1, 2012.

Full Text

Sam, W-J, Chamberlain, CE, Lee, S-J, Goldstein, JA, Hale, DA, Mannon, RB, Kirk, AD, and Hon, YY. "Associations of ABCB1 and IL-10 genetic polymorphisms with sirolimus-induced dyslipidemia in renal transplant recipients." Transplantation 94, no. 9 (November 2012): 971-977.

Full Text

Charafeddine, AH, Kim, EJ, Maynard, DM, Yi, H, Weaver, TA, Gunay-Aygun, M, Russell, M, Gahl, WA, and Kirk, AD. "Platelet-derived CD154: ultrastructural localization and clinical correlation in organ transplantation." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 12, no. 11 (November 2012): 3143-3151.

Full Text

Gupta, NA, Kolachala, VL, Jiang, R, Abramowsky, C, Romero, R, Fifadara, N, Anania, F, Knechtle, S, and Kirk, A. "The glucagon-like peptide-1 receptor agonist Exendin 4 has a protective role in ischemic injury of lean and steatotic liver by inhibiting cell death and stimulating lipolysis." The American journal of pathology 181, no. 5 (November 2012): 1693-1701.

Full Text

Kwun, J, Oh, BC, Gibby, AC, Ruhil, R, Lu, VT, Kim, DW, Page, EK, Bulut, OP, Song, MQ, Farris, AB, Kirk, AD, Knechtle, SJ, and Iwakoshi, NN. "Patterns of de novo allo B cells and antibody formation in chronic cardiac allograft rejection after alemtuzumab treatment." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 12, no. 10 (October 2012): 2641-2651.

Full Text

Best, V, Knechtle, SJ, Kirk, AD, and Grakoui, A. "Potential role for intrahepatic CD34+cells in immunity to hepatitis C virus." October 2012.

Scholars@Duke

Pages