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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Distinguished Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants


Cendales, L., R. Bray, H. Gebel, L. Brewster, R. Elbein, D. Farthing, M. Song, et al. “Tacrolimus to Belatacept Conversion Following Hand Transplantation: A Case Report..” Am J Transplant 15, no. 8 (August 2015): 2250–55.

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Suessmuth, Y., R. Mukherjee, B. Watkins, D. T. Koura, K. Finstermeier, C. Desmarais, L. Stempora, et al. “CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRbeta repertoire.” Blood 125 (June 18, 2015): 3835–50.


Suessmuth, Yvonne, Rithun Mukherjee, Benjamin Watkins, Divya T. Koura, Knut Finstermeier, Cindy Desmarais, Linda Stempora, et al. “CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire..” Blood 125, no. 25 (June 18, 2015): 3835–50.

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Mou, Danny, Jaclyn E. Espinosa, Linda Stempora, Neal N. Iwakoshi, and Allan D. Kirk. “Viral-induced CD28 loss evokes costimulation independent alloimmunity..” J Surg Res 196, no. 2 (June 15, 2015): 241–46.

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Freedman, B. I., B. A. Julian, S. O. Pastan, A. K. Israni, D. Schladt, M. D. Gautreaux, V. Hauptfeld, et al. “Apolipoprotein L1 gene variants in deceased organ donors are associated with renal allograft failure..” Am J Transplant 15, no. 6 (June 2015): 1615–22.

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Beasley, Georgia M., Theodore N. Pappas, and Allan D. Kirk. “Procedure Delegation by Attending Surgeons Performing Concurrent Operations in Academic Medical Centers: Balancing Safety and Efficiency..” Ann Surg 261, no. 6 (June 2015): 1044–45.

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Martin, B. M., K. P. Samy, M. C. Lowe, P. W. Thompson, J. Cano, A. B. Farris, M. Song, et al. “Dual islet transplantation modeling of the instant blood-mediated inflammatory reaction..” Am J Transplant 15, no. 5 (May 2015): 1241–52.

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Lo, D. J., D. J. Anderson, M. Song, F. Leopardi, A. B. Farris, E. Strobert, S. Chapin, B. Devens, E. Karrer, and A. D. Kirk. “A pilot trial targeting the ICOS-ICOS-L pathway in nonhuman primate kidney transplantation..” Am J Transplant 15, no. 4 (April 2015): 984–92.

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Velazquez, Victoria M., Luke S. Uebelhoer, Manoj Thapa, Chris C. Ibegbu, Cynthia Courtney, Steven E. Bosinger, Joseph F. Magliocca, et al. “Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development..” Hepatology 61, no. 3 (March 2015): 843–56.

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