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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants


Oh, B., J. Yoon, A. Farris, A. Kirk, S. Knechtle, and J. Kwun. “Rapamycin Interferes With Postdepletion Regulatory T Cell Homeostasis and Enhances DSA Formation Corrected by CTLA4-Ig..” Am J Transplant 16, no. 9 (September 2016): 2612–23.

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Kirk, Allan D., Paul S. Malchesky, Ron Shapiro, Steven A. Webber, Hans H. Hirsch, Francisco M. Marty, Rainer Oberbauer, et al. “Introducing The Wiley Transplant Peer Review Network..” Artif Organs 40, no. 7 (July 2016): 635–37.

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Cendales, Linda C., Matthew Levine, Stephen Bartlett, Jennifer Cheeseman, Cinthia I. Drachenberg, Wayne W. Hancock, Marybeth Joshi, et al. “Skin as a harbinger of rejection of underlying structures in VCA: Concordance or discordance?.” In Transplantation, 100:S813–S813. LIPPINCOTT WILLIAMS & WILKINS, 2016.


Anderson, D. J., D. J. Lo, F. Leopardi, M. Song, N. A. Turgeon, E. A. Strobert, J. B. Jenkins, et al. “Anti-Leukocyte Function-Associated Antigen 1 Therapy in a Nonhuman Primate Renal Transplant Model of Costimulation Blockade-Resistant Rejection..” Am J Transplant 16, no. 5 (May 2016): 1456–64.

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Espinosa, J., F. Herr, G. Tharp, S. Bosinger, M. Song, A. B. Farris, R. George, et al. “CD57(+) CD4 T Cells Underlie Belatacept-Resistant Allograft Rejection..” Am J Transplant 16, no. 4 (April 2016): 1102–12.

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Xu, H., K. P. Samy, A. Guasch, S. I. Mead, A. Ghali, A. Mehta, L. Stempora, and A. D. Kirk. “Postdepletion Lymphocyte Reconstitution During Belatacept and Rapamycin Treatment in Kidney Transplant Recipients..” Am J Transplant 16, no. 2 (February 2016): 550–64.

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Freedman, Barry I., Stephen O. Pastan, Ajay K. Israni, David Schladt, Bruce A. Julian, Michael D. Gautreaux, Vera Hauptfeld, et al. “APOL1 Genotype and Kidney Transplantation Outcomes From Deceased African American Donors..” Transplantation 100, no. 1 (January 2016): 194–202.

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Dorr, Casey R., Barry I. Freedman, Pamela J. Hicks, W Mark Brown, Gregory B. Russell, Bruce A. Julian, Stephen O. Pastan, et al. “Deceased-Donor Apolipoprotein L1 Renal-Risk Variants Have Minimal Effects on Liver Transplant Outcomes..” Plos One 11, no. 4 (2016).

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