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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Division: 
Abdominal Transplant Surgery
Faculty Lab: 
Immune Management Laboratory
Program: 
Abdominal Transplant Surgery Fellowship
Duke Surgical Technique and Review (STAR) Course
General Surgery Residency Program
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

In the News

Selected Grants

Publications

Lee, Jaewoo, Jennifer G. Jackman, Jean Kwun, Miriam Manook, Angelo Moreno, Eric A. Elster, Allan D. Kirk, Kam W. Leong, and Bruce A. Sullenger. “Nucleic acid scavenging microfiber mesh inhibits trauma-induced inflammation and thrombosis..” Biomaterials 120 (March 2017): 94–102. https://doi.org/10.1016/j.biomaterials.2016.12.024.

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Zheng, H. B., B. Watkins, V. Tkachev, S. Yu, D. Tran, S. Furlan, K. Zeleski, et al. “The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism but With a Significant Risk of CMV Reactivation and Disease in Rhesus Macaques..” Am J Transplant 17, no. 3 (March 2017): 657–70. https://doi.org/10.1111/ajt.14006.

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Roedder, Silke, Tara Sigdel, Szu-Chuan Hsieh, Jennifer Cheeseman, Diana Metes, Camila Macedo, Elaine F. Reed, et al. “Expression of Mitochondrial-Encoded Genes in Blood Differentiate Acute Renal Allograft Rejection..” Front Med (Lausanne) 4 (2017). https://doi.org/10.3389/fmed.2017.00185.

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George, Roshan P., Aneesh K. Mehta, Sebastian D. Perez, Pamela Winterberg, Jennifer Cheeseman, Brandi Johnson, Jean Kwun, et al. “Premature T Cell Senescence in Pediatric CKD..” J Am Soc Nephrol 28, no. 1 (January 2017): 359–67. https://doi.org/10.1681/ASN.2016010053.

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Land, W. G., P. Agostinis, S. Gasser, A. D. Garg, and A. Linkermann. “DAMP-Induced Allograft and Tumor Rejection: The Circle Is Closing..” Am J Transplant 16, no. 12 (December 2016): 3322–37. https://doi.org/10.1111/ajt.14012.

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Klintmalm, G. B., F. Vincenti, and A. Kirk. “Steroid-Responsive Acute Rejection Should Not Be the End Point for Immunosuppressive Trials..” Am J Transplant 16, no. 11 (November 2016): 3077–78. https://doi.org/10.1111/ajt.13889.

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Darrabie, Marcus D., Jaewoo Lee, Jennifer Cheeseman, Alexander T. Limkakeng, Steven N. Vaslef, Bruce A. Sullenger, and Allan D. Kirk. “Toll-Like Receptor Signaling as a Prognostic Tool in Trauma Patients.” In Journal of the American College of Surgeons, 223:S159–60. Elsevier BV, 2016. https://doi.org/10.1016/j.jamcollsurg.2016.06.346.

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Chinnadurai, Raghavan, Ian B. Copland, Marco A. Garcia, Christopher T. Petersen, Christopher N. Lewis, Edmund K. Waller, Allan D. Kirk, and Jacques Galipeau. “Cryopreserved Mesenchymal Stromal Cells Are Susceptible to T-Cell Mediated Apoptosis Which Is Partly Rescued by IFNγ Licensing..” Stem Cells 34, no. 9 (September 2016): 2429–42. https://doi.org/10.1002/stem.2415.

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Kirk, A. D., P. S. Malchesky, R. Shapiro, S. A. Webber, H. H. Hirsch, F. M. Marty, R. Oberbauer, et al. “Introducing the Wiley Transplant Peer Review Network..” Am J Transplant 16, no. 9 (September 2016): 2505–7. https://doi.org/10.1111/ajt.13965.

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