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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants

Publications

Newell, Kenneth A., Adam Asare, Allan D. Kirk, Trang Gisler, Manikkam Suthanthiran, William Burlingham, William Marks, Laurence Turka, and Vicki Seyfert-Margolis. “A unique B cell signature associated with operational tolerance.” In American Journal of Transplantation, 8:316–316. BLACKWELL PUBLISHING, 2008.

Scholars@Duke

Rigby, M. R., A. M. Trexler, H. Bello-Labom, A. D. Kirk, T. C. Pearson, L. Kean, and C. P. Larsen. “Antagonism of signaling through CD28 or LFA-1, but not CD154, result in abortive activation of antigen-stimulated T cells.” In American Journal of Transplantation, 8:624–624. BLACKWELL PUBLISHING, 2008.

Scholars@Duke

Rigby, M. R., A. M. Trexler, H. Bello-Labom, A. D. Kirk, T. C. Pearson, L. Kean, and C. P. Larsen. “Antagonism of signaling through CD28 or LFA-1, but not CD154, result in abortive activation of antigen-stimulated T cells.” In American Journal of Transplantation, 8:624–624. BLACKWELL PUBLISHING, 2008.

Scholars@Duke

Ford, Mandy L., Craig M. Steeds, Maylene E. Wagener, Allan D. Kirk, and Christian P. Larsen. “CD8+ memory T cells specific for a single surrogate minor antigen are sufficient to inhibit transplant tolerance induced by CTLA-4 ig and anti-CD154.” In American Journal of Transplantation, 8:293–293. BLACKWELL PUBLISHING, 2008.

Scholars@Duke

Ford, Mandy L., Craig M. Steeds, Maylene E. Wagener, Allan D. Kirk, and Christian P. Larsen. “CD8+ memory T cells specific for a single surrogate minor antigen are sufficient to inhibit transplant tolerance induced by CTLA-4 ig and anti-CD154.” In American Journal of Transplantation, 8:293–293. BLACKWELL PUBLISHING, 2008.

Scholars@Duke

Shen, L. Y., A. Agarwal, N. A. Turgeon, C. P. Larsen, T. C. Pearson, R. A. Bray, H. M. Gebel, A. D. Kirk, and K. E. Kokko. “Combined liver-kidney transplantation across a positive flow crossmatch: A cause for concern?.” In American Journal of Transplantation, 8:337–337. BLACKWELL PUBLISHING, 2008.

Scholars@Duke

Shen, L. Y., A. Agarwal, N. A. Turgeon, C. P. Larsen, T. C. Pearson, R. A. Bray, H. M. Gebel, A. D. Kirk, and K. E. Kokko. “Combined liver-kidney transplantation across a positive flow crossmatch: A cause for concern?.” In American Journal of Transplantation, 8:337–337. BLACKWELL PUBLISHING, 2008.

Scholars@Duke

Charafeddine, Ali H., Meral Gunay-Aygun, Timothy A. Weaver, Dawn M. Maynard, Avi Agarwal, Neal Lwakoshi, William A. Gahl, and Allan D. Kirk. “Compartmentalization of platelet derived CD154: Implications for clinical correlation..” In American Journal of Transplantation, 8:494–494. BLACKWELL PUBLISHING, 2008.

Scholars@Duke

Charafeddine, Ali H., Meral Gunay-Aygun, Timothy A. Weaver, Dawn M. Maynard, Avi Agarwal, Neal Lwakoshi, William A. Gahl, and Allan D. Kirk. “Compartmentalization of platelet derived CD154: Implications for clinical correlation..” In American Journal of Transplantation, 8:494–494. BLACKWELL PUBLISHING, 2008.

Scholars@Duke

Cravedi, P., O. Cheng, A. D. Kirk, D. Kleiner, and R. B. Mannon. “Discovering what the eye can't see: Gene expression in baseline biopsies of kidney allografts.” In American Journal of Transplantation, 8:336–336. BLACKWELL PUBLISHING, 2008.

Scholars@Duke

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