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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants


Darrabie, Marcus D., Jennifer Cheeseman, Alexander T. Limkakeng, Joseph Borawski, Bruce A. Sullenger, Eric A. Elster, Allan D. Kirk, and Jaewoo Lee. “Toll-like receptor activation as a biomarker in traumatically injured patients..” J Surg Res 231 (November 2018): 270–77.

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Cendales, Linda C., David S. Ruch, Adela R. Cardones, Guy Potter, Joshua Dooley, Daniel Dore, Jonah Orr, et al. “De novo belatacept in clinical vascularized composite allotransplantation..” Am J Transplant 18, no. 7 (July 2018): 1804–9.

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Belard, Arnaud, Seth Schobel, Matthew Bradley, Benjamin Kyle Potter, Christopher Dente, Timothy Buchman, Allan Kirk, and Eric Elster. “Battlefield to Bedside: Bringing Precision Medicine to Surgical Care..” J Am Coll Surg 226, no. 6 (June 2018): 1093–1102.

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Samy, K. P., R. P. Davis, Q. Gao, B. M. Martin, M. Song, J. Cano, A. B. Farris, et al. “Early barriers to neonatal porcine islet engraftment in a dual transplant model..” Am J Transplant 18, no. 4 (April 2018): 998–1006.

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Xu, He, Victoria A. Bendersky, Todd V. Brennan, Jaclyn R. Espinosa, and Allan D. Kirk. “IL-7 receptor heterogeneity as a mechanism for repertoire change during postdepletional homeostatic proliferation and its relation to costimulation blockade-resistant rejection..” Am J Transplant 18, no. 3 (March 2018): 720–30.

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Belard, Arnaud, Timothy Buchman, Christopher J. Dente, Benjamin K. Potter, Allan Kirk, and Eric Elster. “The Uniformed Services University's Surgical Critical Care Initiative (SC2i): Bringing Precision Medicine to the Critically Ill..” In Mil Med, 183:487–95, 2018.

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Song, M., M. S. Mulvihill, K. D. Williams, B. H. Collins, and A. D. Kirk. “Fatal SV40-associated pneumonia and nephropathy following renal allotransplantation in rhesus macaque..” J Med Primatol 47, no. 1 (February 2018): 81–84.

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Lamanna, Jason J., Juanmarco Gutierrez, Jaclyn R. Espinosa, Jacob Wagner, Lindsey N. Urquia, Cheryl Moreton, C. Victor Hurtig, et al. “Peripheral blood detection of systemic graft-specific xeno-antibodies following transplantation of human neural progenitor cells into the porcine spinal cord..” J Clin Neurosci 48 (February 2018): 173–80.

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Kwun, Jean, Jaeberm Park, John S. Yi, Alton B. Farris, Allan D. Kirk, and Stuart J. Knechtle. “IL-21 Biased Alemtuzumab Induced Chronic Antibody-Mediated Rejection Is Reversed by LFA-1 Costimulation Blockade..” Frontiers in Immunology 9 (January 2018).

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Daneshmand, M. A., and A. D. Kirk. “Immunosuppression in organ transplantation.” In Fischer’s Mastery of Surgery, Seventh Edition, 1:141–50, 2018.