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Xiaoying Shen, PhD

Associate Professor in Surgery
Office: 205 Sorf, 915 S. Lasalle Street, Box 2926, Duke University Medical Center, Durham, NC 27710
Campus Mail: DUMC Box 2926 DUMC, Durham, NC 27710

Education and Training

  • Ph.D., University of California - Davis, 2004

Selected Grants

Publications

Shen, Xiaoying, Haili Tang, Rolando Pajon, Gale Smith, Gregory M. Glenn, Wei Shi, Bette Korber, and David C. Montefiori. “Neutralization of SARS-CoV-2 Variants B.1.429 and B.1.351.” N Engl J Med 384, no. 24 (June 17, 2021): 2352–54. https://doi.org/10.1056/NEJMc2103740.

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Seaton, Kelly E., Aaron Deal, Xue Han, Shuying S. Li, Ashley Clayton, Jack Heptinstall, Ann Duerr, et al. “Meta-analysis of HIV-1 vaccine elicited mucosal antibodies in humans.” Npj Vaccines 6, no. 1 (April 15, 2021): 56. https://doi.org/10.1038/s41541-021-00305-8.

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Shen, Xiaoying, Haili Tang, Charlene McDanal, Kshitij Wagh, William Fischer, James Theiler, Hyejin Yoon, et al. “SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral spike vaccines.” Cell Host Microbe 29, no. 4 (April 14, 2021): 529-539.e3. https://doi.org/10.1016/j.chom.2021.03.002.

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Saunders, Kevin O., Norbert Pardi, Robert Parks, Sampa Santra, Zekun Mu, Laura Sutherland, Richard Scearce, et al. “Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates.” Npj Vaccines 6, no. 1 (April 9, 2021): 50. https://doi.org/10.1038/s41541-021-00307-6.

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Silva de Castro, Isabela, Giacomo Gorini, Rosemarie Mason, Jason Gorman, Massimiliano Bissa, Mohammad A. Rahman, Anush Arakelyan, et al. “Anti-V2 antibodies virus vulnerability revealed by envelope V1 deletion in HIV vaccine candidates.” Iscience 24, no. 2 (February 19, 2021): 102047. https://doi.org/10.1016/j.isci.2021.102047.

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Felber, B., Z. Lu, X. Hu, A. Valentin, M. Rosati, J. A. Weiner, X. Shen, et al. “Comparison of co-immunization of DNA and protein in the same anatomical sites and in contralateral sites to identify mechanisms of protective immune response.” In Journal of the International Aids Society, Vol. 24, 2021.

Scholars@Duke

Shen, Xiaoying, Haili Tang, Charlene McDanal, Kshitij Wagh, Will Fischer, James Theiler, Hyejin Yoon, et al. “SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral Spike vaccines.” Biorxiv, January 29, 2021. https://doi.org/10.1101/2021.01.27.428516.

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Saunders, Kevin O., Norbert Pardi, Robert Parks, Sampa Santra, Zekun Mu, Laura Sutherland, Richard Scearce, et al. “Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates.” Biorxiv, December 31, 2020. https://doi.org/10.1101/2020.12.30.424745.

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Blasi, Maria, Donatella Negri, Kevin O. Saunders, Erich J. Baker, Hannah Stadtler, Celia LaBranche, Benjamin Mildenberg, et al. “Immunogenicity, safety, and efficacy of sequential immunizations with an SIV-based IDLV expressing CH505 Envs.” Npj Vaccines 5, no. 1 (November 18, 2020): 107. https://doi.org/10.1038/s41541-020-00252-w.

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Jones, Rebecca, Eric Scott, LaShanda Cheston, Morgan Gladden, Shalini Jha, Charles Beck, Justin Pollara, et al. “Vaccine-elicited memory B cells expressing ADCC-mediating antibodies lacking recognition of the V2 region did not correlate with protection of NHPs.” In Journal of Medical Primatology, 49:247–48, 2020.

Scholars@Duke

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