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Peter Kent Smith, MD

Mary and Deryl Hart Professor of Surgery, in the School of Medicine
Chief, Division of Cardiovascular and Thoracic Surgery
Professor of Surgery
Division: 
Cardiovascular and Thoracic Surgery
Program: 
General Surgery Residency Program
Office: 8660 Hafs Building, Durham, NC 27710
Campus Mail: DUMC Box 3442 Med Ctr, Durham, NC 27710

Dr. Smith is the Prinicpal Investigator for the Duke site in the Cardiothoracic Surgery Clinical Trials Network (CTSN) and in recent years has focused his research efforts in clinical research. The CTSN is an NHLBI sponsored network developed to promote clinical research in cardiac surgery, and is now entering its 7th year of funding with a commitment now for an additional 5 years. Dr. Smith is the national PI for a randomized clinical trial comparing CABG alone to CABG with mitral repair for moderate ischemic mitral regurgitation. This trial is nearing completion of enrollment, and he is now the PI of a clinical trial of FFR vs angiographically guided CABG expected to begin national enrollment in September of 2013. Duke has participated as a site in 3 additional CTSN trials, and is one of two sites awarded NHLBI funding as a Clinical Skills Education Core. This funding is designed to formally develop surgical clinical trialists and promote clinical research capacity within our specialty. The Duke site has thus far sponsored 6 CTSN scholars who have all received Masters degrees in clinical research, participated in CTSN protocols and other activities of the Network. Additionally, Dr. Smith has been awarded site funding from the Veteran’s Administration to begin VA cooperative clinical research trials at the Durham VA. Through all of these activities, an integration of clinical research, publications, and scholarship with the advancement of clinically effective Thoracic Surgery is the goal.

Education and Training

  • M.D., Duke University, 1977

In the News

Selected Grants

Publications

Wang, A, Wu, A, Wojdyla, D, Lopes, RD, Newby, LK, Newman, MF, Smith, PK, and Alexander, JH. "Dual antiplatelet therapy for perioperative myocardial infarction following CABG surgery (Accepted)." American Heart Journal 199 (May 1, 2018): 150-155.

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Klinger, RY, James, OG, Borges-Neto, S, Bisanar, T, Li, Y-J, Qi, W, Berger, M, Terrando, N, Newman, MF, Doraiswamy, PM, Mathew, JP, Alzheimer’s Disease Neuroimaging Initiative (ADNI) Study Group, , and Neurologic Outcomes Research Group (NORG), . "18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery." Anesthesiology 128, no. 4 (April 2018): 728-744.

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Gulack, BC, Kirkwood, KA, Shi, W, Smith, PK, Alexander, JH, Burks, SG, Gelijns, AC, Thourani, VH, Bell, D, Greenberg, A, Goldfarb, SD, Mayer, ML, Bowdish, ME, and Cardiothoracic Surgical Trials Network (CTSN), . "Secondary surgical-site infection after coronary artery bypass grafting: A multi-institutional prospective cohort study." The Journal of thoracic and cardiovascular surgery 155, no. 4 (April 2018): 1555-1562.e1.

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Williams, JB, Peterson, ED, Albrecht, ÁS, Li, S, Hirji, SA, Ferguson, T, Smith, PK, and Lopes, RD. "Glycemic control in patients undergoing coronary artery bypass graft surgery: Clinical features, predictors, and outcomes." Journal of critical care 42 (December 2017): 328-333.

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Patel, MR, Calhoon, JH, Dehmer, GJ, Grantham, JA, Maddox, TM, Maron, DJ, and Smith, PK. "ACC/AATS/AHA/ASE/ASNC/SCAI/SCCT/STS 2017 Appropriate Use Criteria for Coronary Revascularization in Patients With Stable Ischemic Heart Disease : A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, and Society of Thoracic Surgeons." Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 24, no. 5 (October 2017): 1759-1792.

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Karhausen, JA, Smeltz, AM, Akushevich, I, Cooter, M, Podgoreanu, MV, Stafford-Smith, M, Martinelli, SM, Fontes, ML, and Kertai, MD. "Platelet Counts and Postoperative Stroke After Coronary Artery Bypass Grafting Surgery." Anesthesia and analgesia 125, no. 4 (October 2017): 1129-1139.

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Mack, MJ, Acker, MA, Gelijns, AC, Overbey, JR, Parides, MK, Browndyke, JN, Groh, MA, Moskowitz, AJ, Jeffries, NO, Ailawadi, G, Thourani, VH, Moquete, EG, Iribarne, A, Voisine, P, Perrault, LP, Bowdish, ME, Bilello, M, Davatzikos, C, Mangusan, RF, Winkle, RA, Smith, PK, Michler, RE, Miller, MA, O'Sullivan, KL, Taddei-Peters, WC, Rose, EA, Weisel, RD, Furie, KL, Bagiella, E, Moy, CS, O'Gara, PT, Messé, SR, and Cardiothoracic Surgical Trials Network (CTSN), . "Effect of Cerebral Embolic Protection Devices on CNS Infarction in Surgical Aortic Valve Replacement: A Randomized Clinical Trial." JAMA 318, no. 6 (August 2017): 536-547.

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Posenau, JT, Wojdyla, DM, Shaw, LK, Alexander, KP, Ohman, EM, Patel, MR, Smith, PK, and Rao, SV. "Revascularization Strategies and Outcomes in Elderly Patients With Multivessel Coronary Disease." The Annals of thoracic surgery 104, no. 1 (July 2017): 107-115.

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Patel, MR, Calhoon, JH, Dehmer, GJ, Grantham, JA, Maddox, TM, Maron, DJ, and Smith, PK. "ACC/AATS/AHA/ASE/ASNC/SCAI/SCCT/STS 2017 Appropriate Use Criteria for Coronary Revascularization in Patients With Stable Ischemic Heart Disease: A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, and Society of Thoracic Surgeons." Journal of the American College of Cardiology 69, no. 17 (May 2017): 2212-2241.

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Patel, MR, Calhoon, JH, Dehmer, GJ, Grantham, JA, Maddox, TM, Maron, DJ, and Smith, PK. "ACC/AATS/AHA/ASE/ASNC/SCAI/SCCT/STS 2016 Appropriate Use Criteria for Coronary Revascularization in Patients With Acute Coronary Syndromes : A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, and the Society of Thoracic Surgeons." Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 24, no. 2 (April 2017): 439-463.

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