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Peter Kent Smith, MD

Mary and Deryl Hart Professor of Surgery, in the School of Medicine
Chief, Division of Cardiovascular and Thoracic Surgery
Professor of Surgery
Office: 8660 Hafs Building, Durham, NC 27710
Campus Mail: DUMC Box 3442 Med Ctr, Durham, NC 27710

Dr. Smith is the Prinicpal Investigator for the Duke site in the Cardiothoracic Surgery Clinical Trials Network (CTSN) and in recent years has focused his research efforts in clinical research. The CTSN is an NHLBI sponsored network developed to promote clinical research in cardiac surgery, and is now entering its 7th year of funding with a commitment now for an additional 5 years. Dr. Smith is the national PI for a randomized clinical trial comparing CABG alone to CABG with mitral repair for moderate ischemic mitral regurgitation. This trial is nearing completion of enrollment, and he is now the PI of a clinical trial of FFR vs angiographically guided CABG expected to begin national enrollment in September of 2013. Duke has participated as a site in 3 additional CTSN trials, and is one of two sites awarded NHLBI funding as a Clinical Skills Education Core. This funding is designed to formally develop surgical clinical trialists and promote clinical research capacity within our specialty. The Duke site has thus far sponsored 6 CTSN scholars who have all received Masters degrees in clinical research, participated in CTSN protocols and other activities of the Network. Additionally, Dr. Smith has been awarded site funding from the Veteran’s Administration to begin VA cooperative clinical research trials at the Durham VA. Through all of these activities, an integration of clinical research, publications, and scholarship with the advancement of clinically effective Thoracic Surgery is the goal.

Education and Training

  • M.D., Duke University, 1977

Publications

Blackstone, EH, Chang, HL, Rajeswaran, J, Parides, MK, Ishwaran, H, Li, L, Ehrlinger, J, Gelijns, AC, Moskowitz, AJ, Argenziano, M, DeRose, JJ, Couderc, J-P, Balda, D, Dagenais, F, Mack, MJ, Ailawadi, G, Smith, PK, Acker, MA, O'Gara, PT, Gillinov, AM, and Cardiothoracic Surgical Trials Network Investigators, . "Biatrial maze procedure versus pulmonary vein isolation for atrial fibrillation during mitral valve surgery: New analytical approaches and end points." The Journal of Thoracic and Cardiovascular Surgery 157, no. 1 (January 2019): 234-243.e9.

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Williams, JB, McConnell, G, Allender, JE, Woltz, P, Kane, K, Smith, PK, Engelman, DT, and Bradford, WT. "One-year results from the first US-based enhanced recovery after cardiac surgery (ERAS Cardiac) program." The Journal of Thoracic and Cardiovascular Surgery (December 8, 2018).

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Patel, MR, Calhoon, JH, Dehmer, GJ, Grantham, JA, Maddox, TM, Maron, DJ, and Smith, PK. "Correction to: ACC/AATS/AHA/ASE/ASNC/SCAI/SCCT/STS 2017 Appropriate Use Criteria for Coronary Revascularization in Patients With Stable Ischemic Heart Disease." Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology 25, no. 6 (December 2018): 2191-2192.

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Afilalo, J, Sharma, A, Zhang, S, Brennan, JM, Edwards, FH, Mack, MJ, McClurken, JB, Cleveland, JC, Smith, PK, Shahian, DM, Peterson, ED, and Alexander, KP. "Gait Speed and 1-Year Mortality Following Cardiac Surgery: A Landmark Analysis From the Society of Thoracic Surgeons Adult Cardiac Surgery Database." Journal of the American Heart Association 7, no. 23 (December 2018): e010139-null.

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Ferket, BS, Ailawadi, G, Gelijns, AC, Acker, MA, Hohmann, SF, Chang, HL, Bouchard, D, Meltzer, DO, Michler, RE, Moquete, EG, Voisine, P, Mullen, JC, Lala, A, Mack, MJ, Gillinov, AM, Thourani, VH, Miller, MA, Gammie, JS, Parides, MK, Bagiella, E, Smith, RL, Smith, PK, Hung, JW, Gupta, LN, Rose, EA, O’Gara, PT, Moskowitz, AJ, Taddei-Peters, WC, Buxton, D, Geller, NL, Gordon, D, Jeffries, NO, Lee, A, Moy, CS, Gombos, IK, Ralph, J, Weisel, RD, Gardner, TJ, Ascheim, DD, Moquete, E, Chang, H, Chase, M, Foo, J, Gupta, L, Kirkwood, K, Dobrev, E, Levitan, R, O’Sullivan, K, Overbey, J, Santos, M, Williams, D, Williams, P, Ye, X, Mack, M, Adame, T, Settele, N, Adams, J, Ryan, W, Grayburn, P, Chen, FY, Nohria, A, Cohn, L, Shekar, P, Aranki, S, Couper, G, Davidson, M, Bolman, RM, Lawrence, R, Blackstone, EH, Geither, C, Berroteran, L, Dolney, D, Doud, K, Fleming, S, Palumbo, R, Whitman, C, Sankovic, K, Sweeney, DK, Pattakos, G, Clarke, PA, Argenziano, M, Williams, M, Goldsmith, L, Smith, CR, Naka, Y, Stewart, A, Schwartz, A, Bell, D, Van Patten, D, Sreekanth, S, Alexander, JH, Milano, CA, Glower, DD, Mathew, JP, Harrison, JK, Welsh, S, Berry, MF, Parsa, CJ, Tong, BC, Williams, JB, Ferguson, TB, Kypson, AP, Rodriguez, E, Harris, M, Akers, B, O’Neal, A, Puskas, JD, Guyton, R, Baer, J, Baio, K, Neill, AA, Senechal, M, Dagenais, F, O’Connor, K, Dussault, G, Ballivian, T, Keilani, S, Speir, AM, Magee, P, Ad, N, Keyte, S, Dang, M, Slaughter, M, Headlee, M, Moody, H, Solankhi, N, Birks, E, Groh, MA, Shell, LE, Shepard, SA, Trichon, BH, Nanney, T, Hampton, LC, Mangusan, R, D’Alessandro, DA, DeRose, JJ, Goldstein, DJ, Bello, R, Jakobleff, W, Garcia, M, Taub, C, Spevak, D, Swayze, R, Sookraj, N, Perrault, LP, Basmadjian, A-J, Carrier, M, Cartier, R, Pellerin, M, Tanguay, JF, El-Hamamsy, I, Denault, A, Lacharité, J, Robichaud, S, Horvath, KA, Corcoran, PC, Siegenthaler, MP, Murphy, M, Iraola, M, Greenberg, A, Sai-Sudhakar, C, Hasan, A, McDavid, A, Kinn, B, Pagé, P, Sirois, C, Young, CA, Beach, D, Villanueva, R, Woo, YJ, Mayer, ML, Bowdish, M, Starnes, VA, Shavalle, D, Matthews, R, Javadifar, S, Romar, L, Kron, IL, Johnston, K, Dent, JM, Kern, J, Keim, J, Burks, S, Gahring, K, Bull, DA, Desvigne-Nickens, P, Dixon, DO, Haigney, M, Holubkov, R, Jacobs, A, Miller, F, Murkin, JM, Spertus, J, Wechsler, AS, Sellke, F, McDonald, CL, Byington, R, Dickert, N, Ikonomidis, JS, Williams, DO, Yancy, CW, Fang, JC, Giannetti, N, Richenbacher, W, Rao, V, Furie, KL, Miller, R, Pinney, S, Roberts, WC, Walsh, MN, Hung, J, Zeng, X, Kilcullen, N, Hung, D, Keteyian, S, Aldred, H, Brawner, C, Mathew, J, Browndyke, J, and Toulgoat-Dubois, Y. "Cost-Effectiveness of Mitral Valve Repair Versus Replacement for Severe Ischemic Mitral Regurgitation." Circulation: Cardiovascular Quality and Outcomes 11, no. 11 (November 2018).

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Wang, A, Brennan, JM, Zhang, S, Jung, S-H, Yerokun, B, Cox, ML, Jacobs, JP, Badhwar, V, Suri, RM, Thourani, V, Halkos, ME, Gammie, JS, Gillinov, AM, Smith, PK, and Glower, D. "Robotic Mitral Valve Repair in Older Individuals: An Analysis of The Society of Thoracic Surgeons Database." The Annals of Thoracic Surgery 106, no. 5 (November 2018): 1388-1393.

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Bouabdallaoui, N, Stevens, SR, Doenst, T, Petrie, MC, Al-Attar, N, Ali, IS, Ambrosy, AP, Barton, AK, Cartier, R, Cherniavsky, A, Demondion, P, Desvigne-Nickens, P, Favaloro, RR, Gradinac, S, Heinisch, P, Jain, A, Jasinski, M, Jouan, J, Kalil, RAK, Menicanti, L, Michler, RE, Rao, V, Smith, PK, Zembala, M, Velazquez, EJ, Al-Khalidi, HR, Rouleau, JL, and STICH Trial Investigators, . "Society of Thoracic Surgeons Risk Score and EuroSCORE-2 Appropriately Assess 30-Day Postoperative Mortality in the STICH Trial and a Contemporary Cohort of Patients With Left Ventricular Dysfunction Undergoing Surgical Revascularization." Circulation. Heart Failure 11, no. 11 (November 2018): e005531-null.

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Hernandez, AF, Green, JB, Janmohamed, S, D'Agostino, RB, Granger, CB, Jones, NP, Leiter, LA, Rosenberg, AE, Sigmon, KN, Somerville, MC, Thorpe, KM, McMurray, JJV, Del Prato, S, and Harmony Outcomes committees and investigators, . "Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial." Lancet (London, England) 392, no. 10157 (October 2, 2018): 1519-1529.

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Wang, A, Wu, A, Wojdyla, D, Lopes, RD, Newby, LK, Newman, MF, Smith, PK, and Alexander, JH. "Dual antiplatelet therapy for perioperative myocardial infarction following CABG surgery." American Heart Journal 199 (May 2018): 150-155.

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Klinger, RY, James, OG, Borges-Neto, S, Bisanar, T, Li, Y-J, Qi, W, Berger, M, Terrando, N, Newman, MF, Doraiswamy, PM, Mathew, JP, Alzheimer’s Disease Neuroimaging Initiative (ADNI) Study Group, , and Neurologic Outcomes Research Group (NORG), . "18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery." Anesthesiology 128, no. 4 (April 2018): 728-744.

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