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Herbert Kim Lyerly, MD

George Barth Geller Distinguished Professor of Immunology
Professor of Surgery
Professor in Immunology
Professor of Pathology
Office: 203 Research Drive, Rm 433B, Box 2606, Durham, NC 27710
Campus Mail: DUMC Box 2606 Med Ctr, Durham, NC 27710

Education and Training

  • M.D., University of California - Los Angeles, 1983

Selected Grants

Publications

Berend, K. R., J. U. Jung, T. J. Boyle, J. M. DiMaio, S. A. Mungal, R. C. Desrosiers, and H. K. Lyerly. “Phenotypic and functional consequences of herpesvirus saimiri infection of human CD8+ cytotoxic T lymphocytes.” J Virol 67, no. 10 (October 1993): 6317–21. https://doi.org/10.1128/JVI.67.10.6317-6321.1993.

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Boyle, T. J., K. R. Berend, J. M. DiMaio, R. E. Coles, D. F. Via, and H. K. Lyerly. “Adoptive transfer of cytotoxic T lymphocytes for the treatment of transplant-associated lymphoma.” Surgery 114, no. 2 (August 1993): 218–25.

Scholars@Duke

MALIM, M. H., W. W. FREIMUTH, J. LIU, T. J. BOYLE, H. K. LYERLY, B. R. CULLEN, and G. J. NABEL. “TRANSDOMINANT REV PROTEIN INHIBITS HIV REPLICATION WITHOUT AFFECTING T-CELL FUNCTION.” In Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 6:669–669. LIPPINCOTT-RAVEN PUBL, 1993.

Scholars@Duke

NABEL, G. J., E. G. NABEL, G. E. PLAUTZ, J. LIU, Z. YANG, C. WOFFENDIN, X. GAO, et al. “DIRECT GENE-TRANSFER AND MOLECULAR INTERVENTIONS FOR AIDS AND CANCER.” In Journal of Cellular Biochemistry, 185–185. WILEY-LISS, 1993.

Scholars@Duke

Coles, R. E., T. J. Boyle, J. Kurtzberg, A. Stewart, W. P. Peters, and H. K. Lyerly. “Retroviral gene transduction of circulating progenitor cells in patients with metastatic breast cancer.” Surg Oncol 2, no. 1 (1993): 1–6. https://doi.org/10.1016/0960-7404(93)90038-z.

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Malim, M. H., W. W. Freimuth, J. Liu, T. J. Boyle, H. K. Lyerly, B. R. Cullen, and G. J. Nabel. “Stable expression of transdominant Rev protein in human T cells inhibits human immunodeficiency virus replication.” J Exp Med 176, no. 4 (October 1, 1992): 1197–1201. https://doi.org/10.1084/jem.176.4.1197.

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MALIM, M. H., W. W. FREIMUTH, J. LIU, T. J. BOYLE, H. K. LYERLY, B. R. CULLEN, and G. J. NABEL. “TRANSDOMINANT REV PROTEIN INHIBITS HIV REPLICATION WITHOUT AFFECTING T-CELL FUNCTION.” In Clinical Research, 40:A701–A701. SLACK INC, 1992.

Scholars@Duke

Chen, H., T. J. Boyle, M. H. Malim, B. R. Cullen, and H. K. Lyerly. “Derivation of a biologically contained replication system for human immunodeficiency virus type 1.” Proc Natl Acad Sci U S A 89, no. 16 (August 15, 1992): 7678–82. https://doi.org/10.1073/pnas.89.16.7678.

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Boyle, T. J., M. Tamburini, K. R. Berend, A. M. Kizilbash, M. J. Borowitz, and H. K. Lyerly. “Human B-cell lymphoma in severe combined immunodeficient mice after active infection with Epstein-Barr virus.” Surgery 112, no. 2 (August 1992): 378–86.

Scholars@Duke

Hwang, S. S., T. J. Boyle, H. K. Lyerly, and B. R. Cullen. “Identification of envelope V3 loop as the major determinant of CD4 neutralization sensitivity of HIV-1.” Science 257, no. 5069 (July 24, 1992): 535–37. https://doi.org/10.1126/science.1636088.

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