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Herbert Kim Lyerly, MD

George Barth Geller Distinguished Professor of Immunology
Professor of Surgery
Professor in Immunology
Professor of Pathology
Office: 203 Research Drive, Rm 433B, Box 2606, Durham, NC 27710
Campus Mail: DUMC Box 2606 Med Ctr, Durham, NC 27710

Education and Training

  • M.D., University of California - Los Angeles, 1983

Selected Grants

Publications

Lv, Shuzhen, Shuo Wang, Guoliang Qiao, Xiaoli Wang, Xinna Zhou, Fengcai Yan, Yanping Li, et al. “Functional CD3+CD8+PD1- T Cell Accumulation and PD-L1 Expression Increases During Tumor Invasion in DCIS of the Breast.” Clin Breast Cancer 19, no. 5 (October 2019): e617–23. https://doi.org/10.1016/j.clbc.2019.04.001.

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Kim, H., H. Wu, P. Zhong, K. Mahmood, H. K. Lyerly, and X. Jiang. “Small Aperture Ultrasound Transducers for Intracavitary Tissue Ablation.” In Ieee International Ultrasonics Symposium, Ius, 2019-October:1842–45, 2019. https://doi.org/10.1109/ULTSYM.2019.8925925.

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Shaia, Kathryn L., Chaitanya R. Acharya, Stephanie Smeltzer, Herbert K. Lyerly, and Kelly S. Acharya. “Non-invasive diagnosis of endometriosis: using machine learning instead of the operating room.” In Fertility and Sterility, 112:e80–e80. Elsevier BV, 2019. https://doi.org/10.1016/j.fertnstert.2019.07.331.

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Kula, Tomasz, Mohammad H. Dezfulian, Charlotte I. Wang, Nouran S. Abdelfattah, Zachary C. Hartman, Kai W. Wucherpfennig, Herbert Kim Lyerly, and Stephen J. Elledge. “T-Scan: A Genome-wide Method for the Systematic Discovery of T Cell Epitopes.” Cell 178, no. 4 (August 8, 2019): 1016-1028.e13. https://doi.org/10.1016/j.cell.2019.07.009.

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Sun, Yuanyuan, Suya Wang, Hainan Yang, Jiangping Wu, Sha Li, Guoliang Qiao, Shuo Wang, et al. “Impact of synchronized anti-PD-1 with Ad-CEA vaccination on inhibition of colon cancer growth.” Immunotherapy 11, no. 11 (August 2019): 953–66. https://doi.org/10.2217/imt-2019-0055.

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Kaneko, Kensuke, Takuya Osada, Philip F. Hughes, Timothy A. Haystead, Michael A. Morse, and Herbert K. Lyerly. “Abstract 3731: A novel heat shock protein 90-targeted photosensitizer (HS-201) enables enhanced tumor-specific photodynamic therapy of inflammatory breast cancers.” In Tumor Biology. American Association for Cancer Research, 2019. https://doi.org/10.1158/1538-7445.am2019-3731.

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Tsao, Li-Chung, Jun-Ping Wei, Gang-jun Lei, Tao Wang, Xiao-Yi Yang, Cong-Xiao Liu, H Kim Lyerly, and Zachary C. Hartman. “Abstract 3955: Tumor macrophage-mediated antibody dependent cell phagocytosis (ADCP) is theprimary mechanism mediating HER2 mAb (Trastuzumab) anti-tumor responses which can be synergistically enhanced by CD47 innate immune checkpoint blockade.” In Immunology. American Association for Cancer Research, 2019. https://doi.org/10.1158/1538-7445.sabcs18-3955.

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Abe, Shinya, Takuya Osada, Kensuke Kaneko, Pei Zhong, and Herbert K. Lyerly. “Abstract 4071: A novel combination therapy of high intensity focused ultrasound and PDL1 blockades against advanced breast cancer.” In Immunology. American Association for Cancer Research, 2019. https://doi.org/10.1158/1538-7445.am2019-4071.

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Salgado, Roberto, David B. Solit, David L. Rimm, Jan Bogaerts, Renzo Canetta, Tracy Lively, Kim Lyerly, et al. “Addressing the dichotomy between individual and societal approaches to personalised medicine in oncology.” Eur J Cancer 114 (June 2019): 128–36. https://doi.org/10.1016/j.ejca.2019.03.025.

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Zhao, Y., G. Qiao, X. Wang, Y. Song, X. Zhou, N. Jiang, L. Zhou, et al. “Combination of DC/CIK adoptive T cell immunotherapy with chemotherapy in advanced non-small-cell lung cancer (NSCLC) patients: a prospective patients' preference-based study (PPPS).” Clin Transl Oncol 21, no. 6 (June 2019): 721–28. https://doi.org/10.1007/s12094-018-1968-3.

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