Skip to main content

Herbert Kim Lyerly, MD

George Barth Geller Distinguished Professor of Immunology
Professor of Surgery
Professor in Immunology
Professor of Pathology
Office: 203 Research Drive, Rm 433B, Box 2606, Durham, NC 27710
Campus Mail: DUMC Box 2606 Med Ctr, Durham, NC 27710

Education and Training

  • M.D., University of California - Los Angeles, 1983

Selected Grants

Publications

Song, Linan, Shuo Wang, Tong Fang, Xiaoguang Qiu, Xiaoli Wang, Xinna Zhou, Michael A. Morse, et al. “Changes in Peripheral Blood Regulatory T Cells and IL-6 and IL-10 Levels Predict Response of Pediatric Medulloblastoma and Germ Cell Tumors With Residual or Disseminated Disease to Craniospinal Irradiation.” Int J Radiat Oncol Biol Phys 111, no. 2 (October 1, 2021): 479–90. https://doi.org/10.1016/j.ijrobp.2021.04.041.

Full Text

Ginzel, Joshua D., Chaitanya R. Acharya, Veronica Lubkov, Hidetoshi Mori, Peter G. Boone, Lauren K. Rochelle, Wendy L. Roberts, et al. “HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase.” Mol Cancer Res 19, no. 10 (October 2021): 1699–1711. https://doi.org/10.1158/1541-7786.MCR-21-0215.

Full Text

Von Hoff, Daniel D., Gary M. Clark, Charles A. Coltman, Mary L. Disis, S. G. Eckhardt, Lee M. Ellis, Margaret Foti, et al. “A Grant-Based Experiment to Train Clinical Investigators: The AACR/ASCO Methods in Clinical Cancer Research Workshop.” Clin Cancer Res, July 26, 2021. https://doi.org/10.1158/1078-0432.CCR-21-1799.

Full Text

Wang, Jie, Takuya Osada, Michael A. Morse, Frank Calzone, Hai Yan, Dung Thai, and H Kim Lyerly. “Targeting the glucagon receptor signaling pathway as a novel strategy to counteract PI3K inhibitor induced hyperglycemia while sustaining tumor PI3K inhibition.” Leuk Lymphoma 62, no. 7 (July 2021): 1761–64. https://doi.org/10.1080/10428194.2021.1881504.

Full Text

Telli, Melinda L., Hiroshi Nagata, Irene Wapnir, Chaitanya R. Acharya, Kaitlin Zablotsky, Bernard A. Fox, Carlo B. Bifulco, et al. “Intratumoral Plasmid IL12 Expands CD8+ T Cells and Induces a CXCR3 Gene Signature in Triple-negative Breast Tumors that Sensitizes Patients to Anti-PD-1 Therapy.” Clin Cancer Res 27, no. 9 (May 1, 2021): 2481–93. https://doi.org/10.1158/1078-0432.CCR-20-3944.

Full Text

Crosby, Erika J., Hiroshi Nagata, Melinda L. Telli, Chaitanya R. Acharya, Irene Wapnir, Kaitlin Zablotsky, Erica Browning, et al. “Intratumoral delivery of tavokinogene telseplasmid (plasmid IL-12) and electroporation induces an immune signature that predicts successful combination in patients.” In Cancer Research, Vol. 81, 2021.

Scholars@Duke

Crosby, Erika J., H Kim Lyerly, and Zachary C. Hartman. “Cancer vaccines: the importance of targeting oncogenic drivers and the utility of combinations with immune checkpoint inhibitors.” Oncotarget 12, no. 1 (January 5, 2021): 1–3. https://doi.org/10.18632/oncotarget.27861.

Full Text

Yang, Duo, Xiaoli Wang, Xinna Zhou, Jing Zhao, Huabing Yang, Shuo Wang, Michael A. Morse, et al. “Blood microbiota diversity determines response of advanced colorectal cancer to chemotherapy combined with adoptive T cell immunotherapy.” Oncoimmunology 10, no. 1 (2021): 1976953. https://doi.org/10.1080/2162402X.2021.1976953.

Full Text

Rhew, Sung Han, Julia Kravchenko, and H Kim Lyerly. “Exposure to low-dose ambient fine particulate matter PM2.5 and Alzheimer's disease, non-Alzheimer's dementia, and Parkinson's disease in North Carolina.” Plos One 16, no. 7 (2021): e0253253. https://doi.org/10.1371/journal.pone.0253253.

Full Text

Wang, Xiaoli, Guoliang Qiao, Ni Jiang, Michael A. Morse, Xinna Zhou, Shuo Wang, Jiangping Wu, et al. “Serial assessment of circulating T lymphocyte phenotype and receptor repertoire during treatment of non-muscle invasive bladder cancer with adoptive T cell immunotherapy.” Am J Cancer Res 11, no. 4 (2021): 1709–18.

Scholars@Duke

Pages