Skip to main content

Herbert Kim Lyerly, MD

George Barth Geller Professor
Professor of Surgery
Professor in Immunology
Professor of Pathology
Office: 203 Research Drive, Rm 433B, Box 2606, Durham, NC 27710
Campus Mail: DUMC Box 2606 Med Ctr, Durham, NC 27710

Education and Training

  • M.D., University of California at Los Angeles, 1983

Selected Grants

Publications

Wang, X, Wang, S, Morse, MA, Jiang, N, Zhao, Y, Song, Y, Zhou, L, Huang, H, Zhou, X, Hobeika, A, Ren, J, and Lyerly, HK. "Prospective randomized comparative study on rivaroxaban and LMWH for prophylaxis of post-apheresis thrombosis in adoptive T cell immunotherapy cancer patients." Journal of Thrombosis and Thrombolysis 47, no. 4 (May 2019): 505-511.

Full Text

Crosby, EJ, Gwin, W, Blackwell, K, Marcom, PK, Chang, S, Maecker, HT, Broadwater, G, Hyslop, T, Kim, S, Rogatko, A, Lubkov, V, Snyder, JC, Osada, T, Hobeika, AC, Morse, MA, Lyerly, HK, and Hartman, ZC. "Vaccine-Induced Memory CD8+ T Cells Provide Clinical Benefit in HER2 Expressing Breast Cancer: A Mouse to Human Translational Study." Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 25, no. 9 (May 2019): 2725-2736.

Full Text

Cecchini, M, Rubin, EH, Blumenthal, GM, Ayalew, K, Burris, HA, Russell-Einhorn, M, Dillon, H, Lyerly, HK, Reaman, GH, Boerner, S, and LoRusso, PM. "Challenges with Novel Clinical Trial Designs: Master Protocols." Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 25, no. 7 (April 2019): 2049-2057.

Full Text

Qiao, G, Wang, X, Zhou, L, Zhou, X, Song, Y, Wang, S, Zhao, L, Morse, MA, Hobeika, A, Song, J, Yi, X, Xia, X, Ren, J, and Lyerly, HK. "Autologous Dendritic Cell-Cytokine Induced Killer Cell Immunotherapy Combined with S-1 Plus Cisplatin in Patients with Advanced Gastric Cancer: A Prospective Study." Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 25, no. 5 (March 2019): 1494-1504.

Full Text

Wang, J, Ren, X-R, Piao, H, Zhao, S, Osada, T, Premont, RT, Mook, RA, Morse, MA, Lyerly, HK, and Chen, W. "Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy." The Biochemical Journal 476, no. 3 (February 8, 2019): 535-546.

Full Text

Mook, RA, Wang, J, Ren, X-R, Piao, H, Lyerly, HK, and Chen, W. "Identification of novel triazole inhibitors of Wnt/β-catenin signaling based on the Niclosamide chemotype." Bioorganic & Medicinal Chemistry Letters 29, no. 2 (January 2019): 317-321.

Full Text

Lyerly, HK, Osada, T, and Hartman, ZC. "Right Time and Place for IL12: Targeted Delivery Stimulates Immune Therapy." Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 25, no. 1 (January 2019): 9-11.

Full Text

Lyerly, HK, Ren, J, Canetta, R, Kim, GH, Nagai, S, Yamaguchi, T, Hatogai, K, Katayama, H, Da Rocha Dias, S, McManus, D, Soltys, K, Yang, Z, Olopade, O, Goodman, N, Reaman, G, and Gross, T. "Global Development of Anticancer Therapies for Rare Cancers, Pediatric Cancers, and Molecular Subtypes of Common Cancers." Journal of Global Oncology 4 (December 2018): 1-11.

Full Text

Wang, J, Mook, RA, Ren, X-R, Zhang, Q, Jing, G, Lu, M, Spasojevic, I, Lyerly, HK, Hsu, D, and Chen, W. "Identification of DK419, a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth." Bioorganic & Medicinal Chemistry 26, no. 20 (November 2018): 5435-5442.

Full Text

Zhao, Y, Qiao, G, Wang, X, Song, Y, Zhou, X, Jiang, N, Zhou, L, Huang, H, Zhao, J, Morse, MA, Hobeika, A, Ren, J, and Lyerly, HK. "Combination of DC/CIK adoptive T cell immunotherapy with chemotherapy in advanced non-small-cell lung cancer (NSCLC) patients: a prospective patients' preference-based study (PPPS)." Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (October 29, 2018).

Full Text

Pages