Associate Professor of Surgery
Associate Research Professor in Molecular Genetics and Microbiology
Office:
115 Surg Oncol Res Fac, Durham, NC 27710
Campus Mail:
DUMC Box 2926 Med Ctr, Durham, NC 27710
The activities of the Ferrari Laboratory are based on both independent basic research and immune monitoring studies. The research revolves around three main areas of interest: class I-mediated cytotoxic CD8+ T cell responses, antibody-dependent cellular cytotoxicity (ADCC), gene expression in NK and T cellular subsets upon infection with HIV-1. With continuous funding over the last 11 years from the NIH and Bill & Melinda Gates Foundation along with many other productive collaborations within and outside of Duke, the Ferrari Lab has expanded its focus of research to include the ontogeny of HIV-1 specific immune responses that work by eliminating HIV-1 infected cells and how these can be induced by AIDS vaccine candidates.
Education and Training
- M.D., University of Genoa (Italy), 1985
In the News
- Global List of Highly Cited Puts Duke in Top TenNovember 19, 2019
- Duke Faculty Plentiful On ‘Highly Cited’ ListNovember 27, 2018
Selected Grants
- Interdisciplinary Research Training Program in AIDS
- EQAPOL - Years 2017 to 2024 - BASE
- Infectious Diseases in Africa: Correlates of Protection, Lessons from Vaccines and Natural Infection Studies
- Combined Hepatitis B and HIV-1 Envelope Infant Vaccination to Augment T cell Help through Enhanced Linked Recognition
- MGD020 IND enabling studies
- Primate Contract Expansion for Covid-19
- Nonhuman Primate Option 2
- 14th International Conference on HIV Treatment, Pathogenesis, and Prevention Research (INTEREST 2020)
- Targeting Apoptosis and Immune Control of Epstein-Barr Virus Infected Tonsillar B Cells
- Project 2: Synthetic DNA & Novel Env Vaccine for HIV
- HVTN 405/HPTN 1901 Characterizing SARS-CoV-2-specific immunity in convalescent individuals: LC
- Protocol Development Assays
- HVTN Laboratory Center: HVTN Phase 1
- HVTN Laboratory Center: HVTN 118
- Eqapol Opt 1 -2019-2020
- CIVICS Component A
- Impact of Fc N-glycan structure on HIV-specific antibody functions
- CARE Focus 1: Latency Biomarker Project
- CARE Focus 2: Clearance of HIV Antigen-Positive Cells
- 13th International Conference on HIV Treatment, Pathogenesis, and Prevention Research (Interest)
- Infectious Diseases in Africa: Immune Escape and HIV Vaccines
- Exploring Dual-Affinity Re-Targeting Proteins for Cure of Pediatric HIV-1 Infection
- Creation of a bnAbnectin
- IGM Proposal
- 2018 INTEREST Conference
- HIV Vaccine Trials Network: LC P5 PF
- HVTN - A004
- Evaluation of the host immune response and viral molecular phenotype in lung transplant recipients with PTLD
- CARE Duke-UNC Latency Biomarker Supplement Year 2
- 2017 INTEREST Conference
- Nonhuman Primate Core-Option 6
- EQAPOL - Option 6 - 2016 to 2017 - ELISPOT
- EQAPOL Option 5
- Focus 1: Detection of HIV Antigen-Positive Cells
- Invitro Function of DART Molecules (Base)
- Infant immune correlates of perinatal mother to child transmission of HIV
- Intervening with Latent HIV-1 Infection using Gnidimacrin
- 10th INTEREST Workshop on HIV
- HIV Vaccine Trials Network: LC P5 PF
- LC: HIV Vaccine Trials Network: Phase 1 PF
- HIV Envelope-specific functional antibody responses in HIV-exposed, HIV-vaccinated infants
- HIV-1 Gene Suppression by CD8+ T Cells
- AIDS International Training and Research Program
- Poly-functional analyses of vaccine-induced T cell responses
- Correlates of Vaccine Protection Workshop
- International Clinical Trials Unit
- Infectious Diseases in Africa: Measurement of Immune Responses
- Central Laboratory for the HIV Vaccines Trial Network
- NCRR FACSAria Cell Sorter
- Anti-Hiv Ctl And Hiv Suppressive Cd8 Cells
- Anti-Hiv Ctl And Hiv-Suppresive Cd8+ Cells
- Anti-Hiv Ctl And Hiv Suppresive Cd8+ Cells
- Antihiv Ctl And Hiv Suppressive Cd8 Cells