Skip to main content

Gayathri R. Devi, PhD

Associate Director, Research Education
Associate Professor in Surgery
Associate Professor in Pathology
Office: 477 Med.Sci.Res.Bldg. (Msrb1), 2606 DUMC, Durham, NC 27710
Campus Mail: DUMC Box 2606 Med Ctr, Durham, NC 27710

Dr. Devi’s research interests include functional genomics, anti-cancer drug discovery and development, mechanisms of cancer cell signaling, tumor immunity and applications thereof for overcoming therapeutic resistance in cancer.

The lab has established prostate, inflammatory breast cancer and ovarian cellular and tumor models.

Education and Training

  • Ph.D., University of Nebraska, College of Medicine, 1998

Publications

Schirmer, Amelia U., Lucy M. Driver, Megan T. Zhao, Carrow I. Wells, Julie E. Pickett, Sean N. O’Bryne, Benjamin J. Eduful, et al. “Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer.” Mol Ther, August 24, 2021. https://doi.org/10.1016/j.ymthe.2021.08.029.

Full Text

Gearhart-Serna, Larisa M., Moises Tacam, Theodore A. Slotkin, and Gayathri R. Devi. “Analysis of polycyclic aromatic hydrocarbon intake in the US adult population from NHANES 2005-2014 identifies vulnerable subpopulations, suggests interaction between tobacco smoke exposure and sociodemographic factors.” Environ Res 201 (July 1, 2021): 111614. https://doi.org/10.1016/j.envres.2021.111614.

Full Text

Devi, Gayathri R., Pascal Finetti, Michael A. Morse, Seayoung Lee, Alexandre de Nonneville, Steven Van Laere, Jesse Troy, Joseph Geradts, Shannon McCall, and Francois Bertucci. “Expression of X-Linked Inhibitor of Apoptosis Protein (XIAP) in Breast Cancer Is Associated with Shorter Survival and Resistance to Chemotherapy.” Cancers (Basel) 13, no. 11 (June 4, 2021). https://doi.org/10.3390/cancers13112807.

Full Text

Song, Mingqing, Zachary W. Fitch, Kannan P. Samy, Benjamin M. Martin, Qimeng Gao, Robert Patrick Davis, Francis V. Leopardi, et al. “Coagulation, inflammation, and CD46 transgene expression in neonatal porcine islet xenotransplantation.” Xenotransplantation 28, no. 3 (May 2021): e12680. https://doi.org/10.1111/xen.12680.

Full Text

Xie, Xuemei, Jangsoon Lee, Huey Liu, Troy Pearson, Alexander Y. Lu, Debu Tripathy, Gayathri R. Devi, Chandra Bartholomeusz, and Naoto T. Ueno. “Birinapant Enhances Gemcitabine's Antitumor Efficacy in Triple-Negative Breast Cancer by Inducing Intrinsic Pathway-Dependent Apoptosis.” Mol Cancer Ther 20, no. 2 (February 2021): 296–306. https://doi.org/10.1158/1535-7163.MCT-19-1160.

Full Text

Sauer, Scott, Dylan Beinart, Sade M. B. Finn, Sereena L. Kumar, Qing Cheng, Shelley E. Hwang, William Parker, and Gayathri R. Devi. “Hymenolepis diminuta-based helminth therapy in C3(1)-TAg mice does not alter breast tumor onset or progression.” Evol Med Public Health 9, no. 1 (2021): 131–38. https://doi.org/10.1093/emph/eoab007.

Full Text

Gearhart-Serna, Larisa M., John B. Davis, Mohit Kumar Jolly, Nishad Jayasundara, Scott J. Sauer, Richard T. Di Giulio, and Gayathri R. Devi. “A polycyclic aromatic hydrocarbon-enriched environmental chemical mixture enhances AhR, antiapoptotic signaling and a proliferative phenotype in breast cancer cells.” Carcinogenesis 41, no. 12 (December 31, 2020): 1648–59. https://doi.org/10.1093/carcin/bgaa047.

Full Text

Rickard, Ashlyn, Pranalee Patel, Scott J. Sauer, Mark W. Dewhirst, Gregory M. Palmer, and Gayathri R. Devi. “Abstract P1-03-03: Multichannel serial imaging of transgenic, preclinical murine models provides the first quantitative analysis of the unusual growth kinetics and lymph-vascular invasion of patient-derived inflammatory breast cancer cells and tumor emboli.” In Poster Session Abstracts. American Association for Cancer Research, 2020. https://doi.org/10.1158/1538-7445.sabcs19-p1-03-03.

Full Text

Samy, Kannan P., Qimeng Gao, Robert Patrick Davis, Mingqing Song, Zachary W. Fitch, Michael S. Mulvihill, Andrea L. MacDonald, et al. “The role of human CD46 in early xenoislet engraftment in a dual transplant model.” Xenotransplantation 26, no. 6 (November 2019): e12540. https://doi.org/10.1111/xen.12540.

Full Text

Pages