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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants

Publications

MacConmara, M, Nwadei, I, and Kirk, AD. "Immunosuppressive Biologic Agents." In Transplantation of the Liver: Third Edition, 1343-1353. January 28, 2015.

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Ruiz, R, and Kirk, AD. "Long-Term Toxicity of Immunosuppressive Therapy." In Transplantation of the Liver: Third Edition, 1354-1363. January 28, 2015.

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Bray, RA, Brannon, P, Breitenbach, C, Bryan, C, Chen, D-F, Lai, J, McRacken, T, Kirk, A, Kaplan, B, Pearson, T, and Gebel, HM. "The new OPTN kidney allocation policy: potential for inequitable access among highly sensitized patients." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 15, no. 1 (January 2015): 284-285. (Letter)

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Gupta, NA, Kolachala, VL, Jiang, R, Abramowsky, C, Shenoi, A, Kosters, A, Pavuluri, H, Anania, F, and Kirk, AD. "Mitigation of autophagy ameliorates hepatocellular damage following ischemia-reperfusion injury in murine steatotic liver." AJP: Gastrointestinal and Liver Physiology 307, no. 11 (December 1, 2014): G1088-G1099.

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Singh, K, Stempora, L, Harvey, RD, Kirk, AD, Larsen, CP, Blazar, BR, and Kean, LS. "Superiority of Rapamycin Over Tacrolimus in Preserving Nonhuman Primate Treg Half-Life and Phenotype After Adoptive Transfer." American Journal of Transplantation 14, no. 12 (December 2014): 2691-2703.

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Roedder, S, Sigdel, T, Salomonis, N, Hsieh, S, Dai, H, Bestard, O, Metes, D, Zeevi, A, Gritsch, A, Cheeseman, J, Macedo, C, Peddy, R, Medeiros, M, Vincenti, F, Asher, N, Salvatierra, O, Shapiro, R, Kirk, A, Reed, E, and Sarwal, MM. "The kSORT Assay to Detect Renal Transplant Patients at High Risk for Acute Rejection: Results of the Multicenter AART Study." Edited by G Remuzzi. PLoS Medicine 11, no. 11 (November 11, 2014): e1001759-e1001759.

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Mou, D, Espinosa, J, Lo, DJ, and Kirk, AD. "CD28 negative T cells: is their loss our gain?." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 14, no. 11 (November 2014): 2460-2466. (Review)

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Chinnadurai, R, Garcia, M, Sakurai, Y, Lam, W, Kirk, A, Galipeau, J, and Copland, I. "Actin Cytoskeletal Disruption following Cryopreservation Alters the Biodistribution of Human Mesenchymal Stromal Cells In Vivo." Stem Cell Reports 3, no. 1 (July 2014): 60-72.

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Samy, KP, Martin, BM, Turgeon, NA, and Kirk, AD. "Islet cell xenotransplantation: a serious look toward the clinic." Xenotransplantation 21, no. 3 (May 2014): 221-229.

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Kirk, AD, Guasch, A, Xu, H, Cheeseman, J, Mead, SI, Ghali, A, Mehta, AK, Wu, D, Gebel, H, Bray, R, Horan, J, Kean, LS, Larsen, CP, and Pearson, TC. "Renal transplantation using belatacept without maintenance steroids or calcineurin inhibitors." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 14, no. 5 (May 2014): 1142-1151.

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