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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Distinguished Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants

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Publications

Harlan, D. M., and A. D. Kirk. “Anti-CD154 therapy to prevent graft rejection.” Graft 1 (1998): 63–63.

Scholars@Duke

Van der Werf, W. J., A. M. D’Alessandro, S. J. Knechtle, G. Pilli, R. M. Hoffmann, R. H. Judd, J. S. Odorico, et al. “Infant pediatric liver transplantation results equal those for older pediatric patients..” J Pediatr Surg 33, no. 1 (January 1998): 20–23. https://doi.org/10.1016/s0022-3468(98)90353-0.

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Kirk, A. D., L. M. Jacobson, D. M. Heisey, N. A. Fass, H. W. Sollinger, and J. D. Pirsch. “Posttransplant diastolic hypertension: associations with intragraft transforming growth factor-beta, endothelin, and renin transcription..” Transplantation 64, no. 12 (December 27, 1997): 1716–20. https://doi.org/10.1097/00007890-199712270-00015.

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Kirk, A. D., D. M. Harlan, N. N. Armstrong, T. A. Davis, Y. Dong, G. S. Gray, X. Hong, D. Thomas, J. H. Fechner, and S. J. Knechtle. “CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates..” Proc Natl Acad Sci U S A 94, no. 16 (August 5, 1997): 8789–94. https://doi.org/10.1073/pnas.94.16.8789.

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Jerome, K. R., A. D. Kirk, G. Pecher, W. W. Ferguson, and O. J. Finn. “A survivor of breast cancer with immunity to MUC-1 mucin, and lactational mastitis..” Cancer Immunol Immunother 43, no. 6 (January 1997): 355–60. https://doi.org/10.1007/s002620050344.

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Kirk, A. D., D. M. Heisey, A. M. D’Alessandro, S. J. Knechtle, J. S. Odorico, S. C. Rayhill, H. W. Sollinger, and J. D. Pirsch. “Clinical hepatitis after transplantation of hepatitis C virus-positive kidneys: HLA-DR3 as a risk factor for the development of posttransplant hepatitis..” Transplantation 62, no. 12 (December 27, 1996): 1758–62. https://doi.org/10.1097/00007890-199612270-00011.

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Ibrahim, S., A. D. Kirk, and F. Sanfilippo. “Phenotype of infiltrating cells in an ex vivo model of human antiporcine hyperacute cardiac xenograft rejection..” Transplant Proc 28, no. 2 (April 1996).

Scholars@Duke

Rayhill, S. C., M. Heimes, A. D. Kirk, and H. W. Sollinger. “Simultaneous pancreas - kidney transplantation: Recent experience at the University of Wisconsin.” Experimental and Clinical Endocrinology and Diabetes 104, no. 5 (1996): 353–59.

Scholars@Duke

Kirk, A. D., R. R. Bollinger, and O. J. Finn. “Rapid, comprehensive analysis of human cytokine mRNA and its application to the study of acute renal allograft rejection..” Hum Immunol 43, no. 2 (June 1995): 113–28. https://doi.org/10.1016/0198-8859(94)00158-m.

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Rayhill, S. C., A. D. Kirk, J. S. Odorico, D. M. Heisey, C. B. Cangro, J. D. Pirsch, A. M. D’Alessandro, S. J. Knechtle, and H. W. Sollinger. “Simultaneous pancreas-kidney transplantation at the University of Wisconsin..” Clin Transpl, 1995, 261–69.

Scholars@Duke

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