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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Distinguished Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants

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Publications

Kirk, A. D., P. J. Blair, D. K. Tadaki, H. Xu, and D. M. Harlan. “The role of CD154 in organ transplant rejection and acceptance..” Philos Trans R Soc Lond B Biol Sci 356, no. 1409 (May 29, 2001): 691–702. https://doi.org/10.1098/rstb.2001.0855.

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Hoffmann, S. C., E. M. Stanley, E. D. Cox, N. Craighead, S. P. Perfetto, D. M. Harlan, A. D. Kirk, and P. J. Blair. “The polymorphism at-330 in the interleukin-2 gene results in a significant increase in IL-2 protein following co-stimulation of peripheral blood lymphocytes with anti-CD3/CD28..” In Faseb Journal, 15:A1055–A1055. FEDERATION AMER SOC EXP BIOL, 2001.

Scholars@Duke

Hoffmann, S. C., E. M. Stanley, E. D. Cox, B. S. DiMercurio, D. E. Koziol, D. M. Harlan, A. D. Kirk, and P. J. Blair. “Correlation of cytokine gene polymorphic inheritance and in vitro cytokine production in anti-CD3/CD28 stimulated peripheral blood lymphocytes.” In Faseb Journal, 15:A666–A666. FEDERATION AMER SOC EXP BIOL, 2001.

Scholars@Duke

Abbott, K. C., J. D. Oliver, I. Hypolite, L. L. Lepler, A. D. Kirk, C. W. Ko, C. A. Hawkes, C. A. Jones, and L. Y. Agodoa. “Hospitalizations for bacterial septicemia after renal transplantation in the united states..” Am J Nephrol 21, no. 2 (March 2001): 120–27. https://doi.org/10.1159/000046234.

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Xu, H., E. Elster, D. Batty, J. Berning, L. Burkly, R. Kampen, S. Swanson, D. Tadaki, D. Harlan, and A. Kirk. “Effects of dose and duration of anti-CD154 antibody therapy in preventing renal allograft rejection in a nonhuman primate model..” Transplant Proc 33, no. 1–2 (February 2001): 223–24. https://doi.org/10.1016/s0041-1345(00)01983-7.

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Abbott, K. C., E. S. Sawyers, J. D. Oliver, C. W. Ko, A. D. Kirk, P. G. Welch, T. G. Peters, and L. Y. Agodoa. “Graft loss due to recurrent focal segmental glomerulosclerosis in renal transplant recipients in the United States..” Am J Kidney Dis 37, no. 2 (February 2001): 366–73. https://doi.org/10.1053/ajkd.2001.21311.

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Elster, E. A., H. Xu, D. K. Tadaki, L. C. Burkly, J. D. Berning, R. E. Baumgartner, F. Cruzata, N. B. Patterson, D. M. Harlan, and A. D. Kirk. “Primate skin allotransplantation with anti-CD154 monotherapy..” Transplantation Proceedings 33, no. 1–2 (February 2001): 675–76. https://doi.org/10.1016/s0041-1345(00)02197-7.

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Irwin, Garth, and Alexander D. Kirk. “Intermediates in chromium(III) photochemistry.” Coordination Chemistry Reviews 211, no. 1 (January 2001): 25–43. https://doi.org/10.1016/s0010-8545(00)00281-2.

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Leitman, S. F., A. D. Kirk, D. S. Gladden, and J. Kopp. “Plasma exchange in the treatment of recurrent focal segmental glomerulosclerosis (FSGS) following renal transplant.” In Transfusion, 40:54S-55S. AMER ASSOC BLOOD BANKS, 2000.

Scholars@Duke

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