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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants


"Introducing the Wiley Transplant Peer Review Network." Transplant International : Official Journal of the European Society for Organ Transplantation 29, no. 8 (August 2016): 839-841.

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Kirk, AD, Malchesky, PS, Shapiro, R, Webber, SA, Hirsch, HH, Marty, FM, Oberbauer, R, Wekerle, T, Bühler, LH, Labbate, A, Perry, K, and Wielgus, J. "Introducing The Wiley Transplant Peer Review Network." Artificial Organs 40, no. 7 (July 2016): 635-637.

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Cendales, LC, Levine, M, Bartlett, S, Cheeseman, J, Drachenberg, CI, Hancock, WW, Joshi, M, Kirk, AD, Frank, L, Levin, S, Uluer, M, Selim, A, Song, M, Twaddell, WS, Wang, L, Wang, Z, and Barth, RN. "Skin as a harbinger of rejection of underlying structures in VCA: Concordance or discordance?.": LIPPINCOTT WILLIAMS & WILKINS, July 1, 2016.


Espinosa, JR, Samy, KP, and Kirk, AD. "Memory T cells in organ transplantation: progress and challenges." Nature Reviews. Nephrology 12, no. 6 (June 2016): 339-347. (Review)

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Anderson, DJ, Lo, DJ, Leopardi, F, Song, M, Turgeon, NA, Strobert, EA, Jenkins, JB, Wang, R, Reimann, KA, Larsen, CP, and Kirk, AD. "Anti-Leukocyte Function-Associated Antigen 1 Therapy in a Nonhuman Primate Renal Transplant Model of Costimulation Blockade-Resistant Rejection." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 16, no. 5 (May 2016): 1456-1464.

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Espinosa, J, Herr, F, Tharp, G, Bosinger, S, Song, M, Farris, AB, George, R, Cheeseman, J, Stempora, L, Townsend, R, Durrbach, A, and Kirk, AD. "CD57(+) CD4 T Cells Underlie Belatacept-Resistant Allograft Rejection." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 16, no. 4 (April 2016): 1102-1112.

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Xu, H, Samy, KP, Guasch, A, Mead, SI, Ghali, A, Mehta, A, Stempora, L, and Kirk, AD. "Postdepletion Lymphocyte Reconstitution During Belatacept and Rapamycin Treatment in Kidney Transplant Recipients." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 16, no. 2 (February 2016): 550-564.

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Freedman, BI, Pastan, SO, Israni, AK, Schladt, D, Julian, BA, Gautreaux, MD, Hauptfeld, V, Bray, RA, Gebel, HM, Kirk, AD, Gaston, RS, Rogers, J, Farney, AC, Orlando, G, Stratta, RJ, Mohan, S, Ma, L, Langefeld, CD, Bowden, DW, Hicks, PJ, Palmer, ND, Palanisamy, A, Reeves-Daniel, AM, Brown, WM, and Divers, J. "APOL1 Genotype and Kidney Transplantation Outcomes From Deceased African American Donors." Transplantation 100, no. 1 (January 2016): 194-202.

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Dorr, CR, Freedman, BI, Hicks, PJ, Brown, WM, Russell, GB, Julian, BA, Pastan, SO, Gautreaux, MD, Muthusamy, A, Chinnakotla, S, Hauptfeld, V, Bray, RA, Kirk, AD, Divers, J, and Israni, AK. "Deceased-Donor Apolipoprotein L1 Renal-Risk Variants Have Minimal Effects on Liver Transplant Outcomes." Plos One 11, no. 4 (January 2016): e0152775-null.

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Cooper, DKC, Bottino, R, Gianello, P, Graham, M, Hawthorne, WJ, Kirk, AD, Korsgren, O, Park, C-G, and Weber, C. "First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--Chapter 4: pre-clinical efficacy and complication data required to justify a clinical trial." Xenotransplantation 23, no. 1 (January 2016): 46-52.

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