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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants

Publications

Espinosa, J, Herr, F, Tharp, G, Bosinger, S, Song, M, Farris, AB, George, R, Cheeseman, J, Stempora, L, Townsend, R, Durrbach, A, and Kirk, AD. "CD57(+) CD4 T Cells Underlie Belatacept-Resistant Allograft Rejection." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 16, no. 4 (April 2016): 1102-1112.

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Xu, H, Samy, KP, Guasch, A, Mead, SI, Ghali, A, Mehta, A, Stempora, L, and Kirk, AD. "Postdepletion Lymphocyte Reconstitution During Belatacept and Rapamycin Treatment in Kidney Transplant Recipients." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 16, no. 2 (February 2016): 550-564.

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Freedman, BI, Pastan, SO, Israni, AK, Schladt, D, Julian, BA, Gautreaux, MD, Hauptfeld, V, Bray, RA, Gebel, HM, Kirk, AD, Gaston, RS, Rogers, J, Farney, AC, Orlando, G, Stratta, RJ, Mohan, S, Ma, L, Langefeld, CD, Bowden, DW, Hicks, PJ, Palmer, ND, Palanisamy, A, Reeves-Daniel, AM, Brown, WM, and Divers, J. "APOL1 Genotype and Kidney Transplantation Outcomes From Deceased African American Donors." Transplantation 100, no. 1 (January 2016): 194-202.

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Dorr, CR, Freedman, BI, Hicks, PJ, Brown, WM, Russell, GB, Julian, BA, Pastan, SO, Gautreaux, MD, Muthusamy, A, Chinnakotla, S, Hauptfeld, V, Bray, RA, Kirk, AD, Divers, J, and Israni, AK. "Deceased-Donor Apolipoprotein L1 Renal-Risk Variants Have Minimal Effects on Liver Transplant Outcomes." Plos One 11, no. 4 (January 2016): e0152775-null.

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Cooper, DKC, Bottino, R, Gianello, P, Graham, M, Hawthorne, WJ, Kirk, AD, Korsgren, O, Park, C-G, and Weber, C. "First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--Chapter 4: pre-clinical efficacy and complication data required to justify a clinical trial." Xenotransplantation 23, no. 1 (January 2016): 46-52.

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Newell, KA, Asare, A, Sanz, I, Wei, C, Rosenberg, A, Gao, Z, Kanaparthi, S, Asare, S, Lim, N, Stahly, M, Howell, M, Knechtle, S, Kirk, A, Marks, WH, Kawai, T, Spitzer, T, Tolkoff-Rubin, N, Sykes, M, Sachs, DH, Cosimi, AB, Burlingham, WJ, Phippard, D, and Turka, LA. "Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 15, no. 11 (November 2015): 2908-2920.

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Elder, RW, George, RP, McCabe, NM, Rodriguez, FH, Book, WM, Mahle, WT, and Kirk, AD. "Immunologic Aging in Adults with Congenital Heart Disease: Does Infant Sternotomy Matter?." Pediatric cardiology 36, no. 7 (October 2015): 1411-1416.

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Lo, DJ, and Kirk, AD. "Immune responses to transplants." In Transplant Immunology, 142-163. September 12, 2015.

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Ma, J, Divers, J, Palmer, ND, Julian, BA, Israni, AK, Schladt, D, Pastan, SO, Chattrabhuti, K, Gautreaux, MD, Hauptfeld, V, Bray, RA, Kirk, AD, Brown, WM, Gaston, RS, Rogers, J, Farney, AC, Orlando, G, Stratta, RJ, Guan, M, Palanisamy, A, Reeves-Daniel, AM, Bowden, DW, Langefeld, CD, Hicks, PJ, Ma, L, and Freedman, BI. "Deceased donor multidrug resistance protein 1 and caveolin 1 gene variants may influence allograft survival in kidney transplantation." Kidney international 88, no. 3 (September 2015): 584-592.

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Forsberg, JA, Potter, BK, Wagner, MB, Vickers, A, Dente, CJ, Kirk, AD, and Elster, EA. "Lessons of War: Turning Data Into Decisions." EBioMedicine 2, no. 9 (September 2015): 1235-1242.

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