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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants

Publications

Aronson, Solomon, Gavin Martin, Padma Gulur, Mike E. Lipkin, Sandhya A. Lagoo-Deenadayalan, Christopher R. Mantyh, David E. Attarian, Joseph P. Mathew, and Allan D. Kirk. “Preoperative Optimization: A Continued Call to Action..” Anesth Analg, October 15, 2019. https://doi.org/10.1213/ANE.0000000000004492.

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Xu, He, Aneesh K. Mehta, Qimeng Gao, Hui-Jie Lee, Ada Ghali, Antonio Guasch, and Allan D. Kirk. “B cell reconstitution following alemtuzumab induction under a belatacept-based maintenance regimen..” Am J Transplant, October 9, 2019. https://doi.org/10.1111/ajt.15639.

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Blew, Kathryn H., Annabelle Chua, John Foreman, Rasheed Gbadegesin, Annette Jackson, Shashi Nagaraj, Rebecca Sadun, Del Wigfall, Allan D. Kirk, and Eileen T. Chambers. “Tailored use of belatacept in adolescent kidney transplantation..” Am J Transplant, September 24, 2019. https://doi.org/10.1111/ajt.15611.

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Lisboa, Felipe A., Christopher J. Dente, Seth A. Schobel, Vivek Khatri, Benjamin K. Potter, Allan D. Kirk, and Eric A. Elster. “Utilizing Precision Medicine to Estimate Timing for Surgical Closure of Traumatic Extremity Wounds..” Ann Surg 270, no. 3 (September 2019): 535–43. https://doi.org/10.1097/SLA.0000000000003470.

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Eppensteiner, John, Jean Kwun, Uwe Scheuermann, Andrew Barbas, Alexander T. Limkakeng, Maggie Kuchibhatla, Eric A. Elster, Allan D. Kirk, and Jaewoo Lee. “Damage- and pathogen-associated molecular patterns play differential roles in late mortality after critical illness..” Jci Insight 4, no. 16 (August 22, 2019). https://doi.org/10.1172/jci.insight.127925.

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Mulvihill, Michael S., Kannan P. Samy, Qimeng A. Gao, Robin Schmitz, Robert P. Davis, Brian Ezekian, Francis Leopardi, et al. “Secondary lymphoid tissue and costimulation-blockade resistant rejection: A nonhuman primate renal transplant study..” Am J Transplant 19, no. 8 (August 2019): 2350–57. https://doi.org/10.1111/ajt.15365.

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Lin, Liwen, He Xu, Muath Bishawi, FeiFei Feng, Kannan Samy, George Truskey, Andrew S. Barbas, Allan D. Kirk, and Todd V. Brennan. “Circulating mitochondria in organ donors promote allograft rejection..” Am J Transplant 19, no. 7 (July 2019): 1917–29. https://doi.org/10.1111/ajt.15309.

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Samy, Kannan P., Qimeng Gao, Robert Patrick Davis, Mingqing Song, Zachary W. Fitch, Michael S. Mulvihill, Andrea L. MacDonald, et al. “The role of human CD46 in early xenoislet engraftment in a dual transplant model..” Xenotransplantation, June 20, 2019. https://doi.org/10.1111/xen.12540.

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Anderson, Douglas J., Denise J. Lo, Francis Leopardi, Mingqing Song, Elizabeth A. Strobert, Joe B. Jenkins, Christian P. Larsen, and Allan D. Kirk. “Corticosteroids and methotrexate as adjuvants to costimulation blockade in non-human primate renal transplantation..” Clin Transplant 33, no. 6 (June 2019). https://doi.org/10.1111/ctr.13568.

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