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Karen Christine Baker, MD

Associate Professor of Surgery
Division: 

I am a Urologist with fellowship training in male fertility and microsurgery. I utilize surgical, medical, and lifestyle interventions in my practice and I work hand-in-hand with our female reproductive specialists to help couples reach their goal of having a baby.  I arrived at Duke after serving 24 years in the Army as a Urologist and male fertility specialist. During my time in the Army I was a Primary or Associate Investigator for over 30 industry sponsored or investigator initiated clinical and basic science trials.
There is much we do not know about infertility in general and male infertility in particular.  My research interests include quantifying the impact of common medical conditions on male fertility and investigating their pathogenic effects on spermatogenesis and sperm function,  delineating the impact of male factor infertility on outcomes of assisted reproductive techniques, and investigating the efficacy of medical therapy for male factor infertility.  I am also interested in the social, psychological and health impacts of infertility.

Education and Training

  • Crile Research Fellow, Surgery/Urology, Cleveland Clinic, 2012 - 2013
  • Male Infertility Fellow, Surgery, Cleveland Clinic, 2011 - 2012
  • Urology Resident, Surgery, Madigan Army Medical Center, 1998 - 2001
  • General Surgery Resident, Surgery, Madigan Army Medical Center, 1997 - 1998
  • General Surgery Intern, Surgery, Madigan Army Medical Center, 1995 - 1996
  • M.D., Uniformed Services University of the Health Sciences F. Edward Hebert School of Medicine, 1995

Publications

Baker, K, Li, J, and Sabanegh, E. "Analysis of semen parameters in male referrals: impact of reference limits, stratification by fertility categories, predictors of change, and comparison of normal semen parameters in subfertile couples." Fertility and sterility 103, no. 1 (January 2015): 59-65.e5.

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Khurana, KK, Baker, K, Gao, T, and Sabanegh, ES. "The economic burden of genetic tests for the infertile male: a pilot algorithm to improve test predictive value." The Journal of urology 191, no. 4 (April 2014): 1066-1071.

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Baker, K, McGill, J, Sharma, R, Agarwal, A, and Sabanegh, E. "Pregnancy after varicocelectomy: impact of postoperative motility and DFI." Urology 81, no. 4 (April 2013): 760-766.

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Baker, K, and Sabanegh Jr, E. "Obstructive azoospermia: reconstructive techniques and results." Clinics 68 Suppl 1 (January 2013): 61-73. (Review)

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Baker, K, and Sabanegh, E. "The role of microsurgical reconstruction in the era of ICSI." In Microsurgery for Fertility Specialists: A Practical Text, 153-166. January 1, 2013.

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Pugliese, JM, and Baker, KC. "Epidemiology of nephrolithiasis in personnel returning from Operation Iraqi Freedom." Urology 74, no. 1 (July 2009): 56-60.

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DeCastro, BJ, and Baker, KC. "Effect of flexible cystoscopy on serum prostate-specific antigen values." Urology 73, no. 2 (February 2009): 237-240.

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Baker, K, and Costabile, RA. "Demographics, stone characteristic, and treatment of urinary calculi at the 47th Combat Support Hospital during the first 6 months of Operation Iraqi Freedom." Military medicine 172, no. 5 (May 2007): 498-503.

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