Skip to main content

Jean Kwun, PhD

Assistant Professor in Surgery
Office: 362 Jones Building, 207 Research Dr, Durham, NC 27710

Research interests include humoral tolerance to organ transplants in animal model and humans, developing a clinically relevant animal model to study the mechanisms of antibody-mediated rejection (AMR), and establishing a conceptual basis that will translate into therapeutic intervention of AMR.

Education and Training

  • Ph.D., University of Wisconsin - Madison, 2007

Publications

Burghuber, C., E. Kim, J. Kwun, F. Leopardi, A. Gibby, E. Strobert, N. Iwakoshi, and S. Knechtle. “Developing a Nonhuman Primate Model of Sensitization.” In Transplantation, 98:387–88. Ovid Technologies (Wolters Kluwer Health), 2014. https://doi.org/10.1097/00007890-201407151-01268.

Full Text

Burghuber, C., J. Kwun, E. Kim, F. Leopardi, A. Gibby, E. Strobert, N. Iwakoshi, W. Wakwe, A. Adams, and S. Knechtle. “First Experiences With Kidney Transplantation in a Model of Sensitized Rhesus Macaques.” In Transplantation, 98:388–388. Ovid Technologies (Wolters Kluwer Health), 2014. https://doi.org/10.1097/00007890-201407151-01271.

Full Text

Kwun, J., C. Burghuber, E. Page, A. Gibby, N. Iwakoshi, and S. Knechtle. “Successful Desensitization With Combination of Costimulation Blockade and Bortezomib Via Regulating Plasma Cells and Follicular Helper T Cells in Sensitized Rhesus Model.” In Transplantation, 98:378–378. Ovid Technologies (Wolters Kluwer Health), 2014. https://doi.org/10.1097/00007890-201407151-01235.

Full Text

Kwun, J., E. Page, A. Gibby, and S. Knechtle. “The Effect of CCR5 Blockade On De Novo DSA and Long-Term Graft Survival in Non-Human Primate AMR Model.” In Transplantation, 98:26–26. Ovid Technologies (Wolters Kluwer Health), 2014. https://doi.org/10.1097/00007890-201407151-00078.

Full Text

Kwun, J., E. Page, A. Gibby, J. Hong, A. Farris, F. Villinger, and S. Knechtle. “The Effect of Neutralizing BAFF With Atacicept in a T Cell Depletion-Induced Nonhuman Primate AMR Model.” In Transplantation, 98:380–81. Ovid Technologies (Wolters Kluwer Health), 2014. https://doi.org/10.1097/00007890-201407151-01244.

Full Text

Kwun, J., B. Oh, M. MaConmara, H. Song, and S. Knechtle. “The Role of Splenic CD4+CD25+ T reg Cells On Alloreactive B Cell Formation and DSA Production in a Murine CAMR Model.” In Transplantation, 98:385–385. Ovid Technologies (Wolters Kluwer Health), 2014. https://doi.org/10.1097/00007890-201407151-01257.

Full Text

Burghuber, C., E. Kim, J. Kwun, F. Leopardi, A. Gibby, E. Strobert, N. Iwakoshi, and S. Knechtle. “Developing a Nonhuman Primate Model of Sensitization.” In American Journal of Transplantation, 14:387–88, 2014.

Scholars@Duke

Burghuber, C., J. Kwun, E. Kim, F. Leopardi, A. Gibby, E. Strobert, N. Iwakoshi, W. Wakwe, A. Adams, and S. Knechtle. “First Experiences With Kidney Transplantation in a Model of Sensitized Rhesus Macaques.” In American Journal of Transplantation, 14:388–388. WILEY-BLACKWELL, 2014.

Scholars@Duke

Kwun, J., C. Burghuber, E. Page, A. Gibby, N. Iwakoshi, and S. Knechtle. “Successful Desensitization With Combination of Costimulation Blockade and Bortezomib Via Regulating Plasma Cells and Follicular Helper T Cells in Sensitized Rhesus Model.” In American Journal of Transplantation, 14:378–378. WILEY-BLACKWELL, 2014.

Scholars@Duke

Kwun, J., E. Page, A. Gibby, and S. Knechtle. “The Effect of CCR5 Blockade On De Novo DSA and Long-Term Graft Survival in Non-Human Primate AMR Model.” In American Journal of Transplantation, 14:26–26. WILEY-BLACKWELL, 2014.

Scholars@Duke

Pages