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Georgia Doris Tomaras, PhD

Professor in Surgery
Professor in Immunology
Professor in Molecular Genetics and Microbiology
Office: 300 N Duke St, Durham, NC 27701
Campus Mail: DUMC Box 104777 DUMC, Bay 47 Carmichael Bldg, 300 N. Duke St, Durham, NC 27701

Research in the Tomaras Laboratory in the Duke Human Vaccine Institute and Departments of Surgery, Immunology, and Molecular Genetics and Microbiology at Duke University Medical Center, focuses on the identification of immune correlates of protection for preventative vaccines and identification of the mechanisms responsible for potent inhibition of human pathogens.  

Education and Training

  • Postdoctoral Fellowship, Center For Aids Research, Department Of Surgery, Duke University, 1998 - 2001
  • Ph.D., State University of New York Upstate Medical University, 1998

Selected Grants

Publications

Betts, Michael R., Barbara Exley, David A. Price, Anju Bansal, Zenaido Tres Camacho, Vanessa Teaberry, Sadie M. West, et al. “Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection.” Proc Natl Acad Sci U S A 102, no. 12 (March 22, 2005): 4512–17. https://doi.org/10.1073/pnas.0408773102.

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Kaplan, Susan S., Guido Ferrari, Terri Wrin, Nicholas S. Hellmann, Georgia D. Tomaras, Victoria E. Gryszowka, Susan A. Fiscus, Kent J. Weinhold, and Charles B. Hicks. “Longitudinal assessment of immune response and viral characteristics in HIV-infected patients with prolonged CD4(+)/viral load discordance.” Aids Res Hum Retroviruses 21, no. 1 (January 2005): 13–16. https://doi.org/10.1089/aid.2005.21.13.

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Knechtle, S., G. Remuzzi, and R. M. Strieter. “Editorial introductions.” Current Opinion in Organ Transplantation, December 1, 2004.

Scholars@Duke

Blattner, William A., Kris Ann Oursler, Farley Cleghorn, Manhattan Charurat, Anne Sill, Courtenay Bartholomew, Noreen Jack, et al. “Rapid clearance of virus after acute HIV-1 infection: correlates of risk of AIDS.” J Infect Dis 189, no. 10 (May 15, 2004): 1793–1801. https://doi.org/10.1086/386306.

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Morris, Kevin V., Joanne Higgins, Xiaoyng Shen, Jonny T. Stine, and Niels C. Pedersen. “The effects of HHV-8 vMIP-II on SIVmac251 infection and replication competent and incompetent SIVmac239Delta3 vectors.” Virus Res 94, no. 2 (August 2003): 103–12. https://doi.org/10.1016/s0168-1702(03)00138-2.

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Sufka, Susan A., Guido Ferrari, Victoria E. Gryszowka, Terri Wrin, Susan A. Fiscus, Georgia D. Tomaras, Herman F. Staats, et al. “Prolonged CD4+ cell/virus load discordance during treatment with protease inhibitor-based highly active antiretroviral therapy: immune response and viral control.” J Infect Dis 187, no. 7 (April 1, 2003): 1027–37. https://doi.org/10.1086/368359.

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Tomaras, G. D., and M. L. Greenberg. “CD8+ T cell mediated noncytolytic inhibition of human immunodeficiency virus type I.” Front Biosci 6 (March 1, 2001): D575–98. https://doi.org/10.2741/tomaras.

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Hu, Q., J. O. Trent, G. D. Tomaras, Z. Wang, J. L. Murray, S. M. Conolly, J. M. Navenot, A. P. Barry, M. L. Greenberg, and S. C. Peiper. “Identification of ENV determinants in V3 that influence the molecular anatomy of CCR5 utilization.” J Mol Biol 302, no. 2 (September 15, 2000): 359–75. https://doi.org/10.1006/jmbi.2000.4076.

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Tomaras, G. D., S. F. Lacey, C. B. McDanal, G. Ferrari, K. J. Weinhold, and M. L. Greenberg. “CD8+ T cell-mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression.” Proc Natl Acad Sci U S A 97, no. 7 (March 28, 2000): 3503–8. https://doi.org/10.1073/pnas.070521097.

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