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Georgia Doris Tomaras, PhD

Professor in Surgery
Professor in Immunology
Professor in Molecular Genetics and Microbiology
Office: 300 N Duke St, Durham, NC 27701
Campus Mail: DUMC Box 104777 DUMC, Bay 47 Carmichael Bldg, 300 N. Duke St, Durham, NC 27701

Research in the Tomaras Laboratory in the Duke Human Vaccine Institute and Departments of Surgery, Immunology, and Molecular Genetics and Microbiology at Duke University Medical Center, focuses on the identification of immune correlates of protection for preventative vaccines and identification of the mechanisms responsible for potent inhibition of human pathogens.  

Education and Training

  • Postdoctoral Fellowship, Center For Aids Research, Department Of Surgery, Duke University, 1998 - 2001
  • Ph.D., State University of New York Upstate Medical University, 1998

Selected Grants

Publications

Dennison, S. M., M. Reichartz, M. Abraha, R. L. Spreng, U. Wille-Reece, S. Dutta, E. Jongert, S. M. Alam, and G. D. Tomaras. “Magnitude, Specificity, and Avidity of Sporozoite-Specific Antibodies Associate with Protection Status and Distinguish among RTS,S/AS01 Dose Regimens.” Open Forum Infectious Diseases 8, no. 2 (February 1, 2021). https://doi.org/10.1093/ofid/ofaa644.

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Jin, Celina, Jennifer Hill, Bronwyn M. Gunn, Wen-Han Yu, Lindsay C. Dahora, Elizabeth Jones, Mari Johnson, et al. “Vi-specific serological correlates of protection for typhoid fever.” J Exp Med 218, no. 2 (February 1, 2021). https://doi.org/10.1084/jem.20201116.

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Hosseinipour, Mina C., Craig Innes, Sarita Naidoo, Philipp Mann, Julia Hutter, Gita Ramjee, Modulakgotla Sebe, et al. “Phase 1 Human Immunodeficiency Virus (HIV) Vaccine Trial to Evaluate the Safety and Immunogenicity of HIV Subtype C DNA and MF59-Adjuvanted Subtype C Envelope Protein.” Clin Infect Dis 72, no. 1 (January 23, 2021): 50–60. https://doi.org/10.1093/cid/ciz1239.

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Berendam, Stella J., Tiffany M. Styles, Papa K. Morgan-Asiedu, DeAnna Tenney, Amit Kumar, Veronica Obregon-Perko, Katharine J. Bar, et al. “Systematic Assessment of Antiviral Potency, Breadth, and Synergy of Triple Broadly Neutralizing Antibody Combinations against Simian-Human Immunodeficiency Viruses.” J Virol 95, no. 3 (January 13, 2021). https://doi.org/10.1128/JVI.01667-20.

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Tomic, Adriana, Ivan Tomic, Levi Waldron, Ludwig Geistlinger, Max Kuhn, Rachel L. Spreng, Lindsay C. Dahora, et al. “SIMON: Open-Source Knowledge Discovery Platform.” Patterns (N Y) 2, no. 1 (January 8, 2021): 100178. https://doi.org/10.1016/j.patter.2020.100178.

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Pollara, Justin, Matthew Zirui Tay, R Whitney Edwards, Derrick Goodman, Andrew R. Crowley, Robert J. Edwards, David Easterhoff, et al. “Functional Homology for Antibody-Dependent Phagocytosis Across Humans and Rhesus Macaques.” Front Immunol 12 (2021): 678511. https://doi.org/10.3389/fimmu.2021.678511.

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Baden, Lindsey R., Daniel J. Stieh, Michal Sarnecki, Stephen R. Walsh, Georgia D. Tomaras, James G. Kublin, M Juliana McElrath, et al. “Safety and immunogenicity of two heterologous HIV vaccine regimens in healthy, HIV-uninfected adults (TRAVERSE): a randomised, parallel-group, placebo-controlled, double-blind, phase 1/2a study.” Lancet Hiv 7, no. 10 (October 2020): e688–98. https://doi.org/10.1016/S2352-3018(20)30229-0.

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Om, Kier, Dominic Paquin-Proulx, Maria Montero, Kristina Peachman, Xiaoying Shen, Lindsay Wieczorek, Zoltan Beck, et al. “Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge.” Plos Pathog 16, no. 9 (September 2020): e1008764. https://doi.org/10.1371/journal.ppat.1008764.

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Chang, WL William, Jesse D. Deere, Hung T. Kieu, Luis D. Castillo, Kawthar Machmach, Xiaoying Shen, Georgia D. Tomaras, et al. “RhCMV serostatus and vaccine adjuvant impact immunogenicity of RhCMV/SIV vaccines.” Sci Rep 10, no. 1 (August 20, 2020): 14056. https://doi.org/10.1038/s41598-020-71075-x.

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