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Chin Ho Chen, PhD

Professor of Surgery
Office: Sorf Bldg Room 117, Durham, NC 27710
Campus Mail: DUMC Box 2926 Med Ctr, Durham, NC 27710

Education and Training

  • Assistant Professor, Microbiology, Meharry Medical College, 1998 - 2002
  • Assistant Research Professor, Surgery, Duke University, 1997 - 1998
  • Research Associate, Ctr. For Aids Research, Duke University, 1992 - 1997
  • Postdoctoral Fellow, Rheumotology, Duke University, 1991 - 1992
  • Ph.D., University of North Carolina at Chapel Hill, 1991

Publications

Yan, S-L, Li, Y-H, Chen, X-Q, Liu, D, Chen, C-H, and Li, R-T. "Diterpenes from the stem bark of Euphorbia neriifolia and their in vitro anti-HIV activity." Phytochemistry 145 (January 2018): 40-47.

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Dong, M, Quan, L-Q, Dai, W-F, Yan, S-L, Chen, C-H, Chen, X-Q, and Li, R-T. "Anti-inflammatory and Anti-HIV Compounds from Swertia bimaculata." Planta medica 83, no. 17 (November 2017): 1368-1373.

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Chen, C-H, and Poss, KD. "Regeneration Genetics." Annual review of genetics 51 (November 2017): 63-82.

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Dang, Z, Xie, H, Zhu, L, Zhang, Q, Li, Z, Huang, L, and Chen, C-H. "Structure Optimization of Aloperine Derivatives as HIV-1 Entry Inhibitors." ACS medicinal chemistry letters 8, no. 11 (November 2017): 1199-1203.

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Wei, L, Wang, H-L, Huang, L, Chen, C-H, Morris-Natschke, SL, Lee, K-H, and Xie, L. "Drug-like property-driven optimization of 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitors against rilpivirine-resistant mutant virus." Bioorganic & medicinal chemistry letters 27, no. 12 (June 2017): 2788-2792.

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Wada, S, Tanaka, N, Chen, CH, Morris-Natschke, SL, Lee, KH, and Kashiwada, Y. "Anti-HIV natural products (28): preparation of conjugate for 3-O-acyl betulin derivative and AZT as anti-HIV agents." Planta medica 81, no. S 01 (December 14, 2016): S1-S381.

Scholars@Duke

Zhao, Y, Gu, Q, Morris-Natschke, SL, Chen, C-H, and Lee, K-H. "Incorporation of Privileged Structures into Bevirimat Can Improve Activity against Wild-Type and Bevirimat-Resistant HIV-1." Journal of medicinal chemistry 59, no. 19 (October 2016): 9262-9268.

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Huang, L, Lai, W, Zhu, L, and Chen, C-H. "Elimination of HIV-1 latently infected cells by PKC agonist gnidimacrin alone and in combination with a histone deacetylase inhibitor." July 2016.

Scholars@Duke

Zhong, J-D, Zhao, X-W, Chen, X-Q, Li, H-M, Chen, C-H, Xia, X-S, and Li, R-T. "Two new ursane-type triterpenoid saponins from Elsholtzia bodinieri." Archives of pharmacal research 39, no. 6 (June 2016): 771-777.

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Liu, N, Wei, L, Huang, L, Yu, F, Zheng, W, Qin, B, Zhu, D-Q, Morris-Natschke, SL, Jiang, S, Chen, C-H, Lee, K-H, and Xie, L. "Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor Agents: Optimization of Diarylanilines with High Potency against Wild-Type and Rilpivirine-Resistant E138K Mutant Virus." Journal of medicinal chemistry 59, no. 8 (April 12, 2016): 3689-3704.

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