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Paul Schroder, MD, PhD

House Staff
College/University: 
John Carroll University
Medical School: 
The University of Toledo College of Medicine

Clinical and Research Interests

  • Clinical interest: Abdominal organ transplantation
  • Research interest: Transplantation immunology

What were you looking for in a residency program?

A program that would provide me with a well-rounded surgical education, a place that provided opportunity for me to do additional research in the field of transplant immunology, and a place that had a strong abdominal organ transplant program that I could engage with and learn from prior to embarking on fellowship training.

What are the strengths of the Duke program?

The Surgery faculty are excellent and committed to resident learning. The opportunities for research in a multitude of fields related to surgery or surgical sciences is also a strength of the program.

What advice do you have for incoming interns?

The more promising your talents, the harder you will be pushed and the better surgeon you will become. The first year will go by faster than you think. Learn all that you can.

What do you like best about living in Durham and the Triangle?

The cost of living is very reasonable and there are an abundance of outdoor activities to do as well as a temperate climate all year round.

What do you like to do outside of Duke?

I enjoy paddleboarding, playing golf, and music.

Honors and Awards

  • June 2019 Oral Presentation at the American Transplant Congress 2019
    • "Dual targeting desensitization with Carfilzomib plus Lulizumab significantly prolongs kidney transplant survival in allosensitized nonhuman primates." Paul M. Schroder*, Robin Schmitz, Zachary Fitch, Brian Ezekian, Janghoon Yoon, John Yi, Ashley Choi, Andrew Barbas, Frank Leopardi, Bradley Collins, Jean Kwun, and Stuart J. Knechtle
  • June 2019 Poster Presentations at the American Transplant Congress 2019
    • "Novel in vitro germinal center culture system demonstrates more aggressive B cell to plasmablast differentiation in allosensitized nonhuman primates." Paul M. Schroder*, Janghoon Yoon, Robin Schmitz, Zachary Fitch, Jean Kwun, and Stuart J. Knechtle.
    • "Pre-transplant multidimensional flow cytometric analysis of kidney transplant recipients reveals novel immune signature of allograft rejection." Paul M. Schroder*, John S. Yi, Kent J. Weinhold, Cliburn Chan, Marybeth Joshi, Christy Walters, Jean Kwun, and Stuart J. Knechtle.
  • April 2019 *Poster of Distinction Presented at Duke Surgery Research Day 2019
    • "Dual targeting desensitization with Carfilzomib plus Lulizumab significantly prolongs kidney transplant survival in allosensitized nonhuman primates." Paul M. Schroder*, Robin Schmitz, Zachary Fitch, Brian Ezekian, Janghoon Yoon, John Yi, Ashley Choi, Andrew Barbas, Frank Leopardi, Bradley Collins, Jean Kwun, and Stuart J. Knechtle
  • December 2018 Poster Presentations at the Great Lakes Transplant Immunology Forum 2018
    • "Desensitization with Carfilzomib Plus CD28dAb Significantly Improves Kidney Transplant Survival in Allosensitized Nonhuman Primates." Paul M. Schroder*, Robin Schmitz, Zachary Fitch, Brian Ezekian, Janghoon Yoon, Andrew Barbas, Frank Leopardi, Bradley Collins, Jean Kwun, and Stuart J. Knechtle.
    •  "Generation of an Efficient and Reliable Method for Modeling the Germinal Center Reaction In Vitro." Paul M. Schroder*, Janghoon Yoon, Jean Kwun, and Stuart J. Knechtle.
  • June 2018 Poster Presentations at the American Transplant Congress 2018
    • "Humoral Immunity to CMV Remains Intact after Dual Targeting Desensitization in Allosensitized Nonhuman Primates." Paul Schroder*, Brian Ezekian, Frances Saccoccio, Janghoon Yoon, Maria Dennis, Kyle Freischlag, Jean Kwun, Sallie Permar, and Stuart Knechtle.
  • February 2018 Oral Presentation at the Academic Surgical Congress 2018
    • "Identifying Factors that Decrease Utilization of Adjuvant Chemotherapy in Stage III Colon Cancer." Paul M. Schroder*, Megan C. Turner, Brian Ezekian, Zhifei Sun, Mohamed A. Adam, Christopher R. Mantyh, and John Migaly.

Publications

Schroder, P., M. Khattar, R. Deng, C. Baum, B. Mierzejewska, and S. Stepkowski. “TCR-Directed Immune Therapy Restores Self Tolerance and Significantly Prolongs Islet Allograft Survival in Diabetic NOD Mice.” In American Journal of Transplantation, 13:364–364. WILEY-BLACKWELL, 2013.

Scholars@Duke

Mierzejewska, Beata, Magdalena Durlik, Wojciech Lisik, Caitlin Baum, Paul Schroder, Jonathan Kopke, Michael Rees, and Stanislaw Stepkowski. “Current approaches in national kidney paired donation programs.” Annals of Transplantation 18 (March 19, 2013): 112–24. https://doi.org/10.12659/aot.889096.

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Mierzejewska, Beata, Caitlin Baum, Paul Schroder, Annette Blair, Connie Smith, Rene Duquesnoy, Marilyn Marrari, Michael Rees, and Stanislaw Stepkowski. “AGGRESSIVE ACUTE ANTIBODY-MEDIATED REJECTION OF NEGATIVE FLOW CROSSMATCH 3RD KIDNEY TRANSPLANT WITH EXCLUSIVE DISPARITY AT HLA-DP.” In Human Immunology, 74:22–22. ELSEVIER SCIENCE INC, 2013.

Scholars@Duke

Schroder, Paul M., Mithun Khattar, Ronghai Deng, Aini Xie, Wenhao Chen, and Stanislaw M. Stepkowski. “Transient combination therapy targeting the immune synapse abrogates T cell responses and prolongs allograft survival in mice.” Plos One 8, no. 7 (January 2013): e69397. https://doi.org/10.1371/journal.pone.0069397.

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Liang, Wenhua, Linwei Wu, Xiaoting Ling, Paul M. Schroder, Weiqiang Ju, Dongping Wang, Yushu Shang, Yuan Kong, Zhiyong Guo, and Xiaoshun He. “Living donor liver transplantation versus deceased donor liver transplantation for hepatocellular carcinoma: a meta-analysis.” Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 18, no. 10 (October 2012): 1226–36. https://doi.org/10.1002/lt.23490.

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Miyahara, Y., M. Khattar, P. M. Schroder, B. Mierzejewska, R. Deng, R. Han, W. W. Hancock, W. Chen, and S. M. Stepkowski. “Anti-TCRβ mAb induces long-term allograft survival by reducing antigen-reactive T cells and sparing regulatory T cells.” American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 12, no. 6 (June 2012): 1409–18. https://doi.org/10.1111/j.1600-6143.2012.04006.x.

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Stepkowski, S., B. Mierzejewska, H. Sales Filho, L. C. D. M. Sousa, A. da Silva, A. Blair, C. Smith, et al. “EpHLA Software: A Useful Tool To Perform Eplet-Based Donor Selection for Sensitized Patients in a Kidney Paired Donation Program.” In American Journal of Transplantation, 12:540–540. WILEY-BLACKWELL, 2012.

Scholars@Duke

Schroder, P. M., Y. Miyahara, M. Khattar, R. Deng, B. Mierzejewska, W. Chen, and S. M. Stepkowski. “Reprogramming T Cells by an Anti-TCRb mAb to Permanently Accept Heart Allografts.” In American Journal of Transplantation, 12:97–97. WILEY-BLACKWELL, 2012.

Scholars@Duke

Schroder, P. M., M. Khattar, R. Deng, A. Xie, W. Chen, and S. M. Stepkowski. “Therapeutic Alteration of the T Cell Immune Synapse Promotes Selective Deletion of Antigen Responding T Cells.” In American Journal of Transplantation, 12:532–532. WILEY-BLACKWELL, 2012.

Scholars@Duke

Ling, Xiaoting, Jun Xiong, Wenhua Liang, Paul M. Schroder, Linwei Wu, Weiqiang Ju, Yuan Kong, Yushu Shang, Zhiyong Guo, and Xiaoshun He. “Can immune cell function assay identify patients at risk of infection or rejection? A meta-analysis.” Transplantation 93, no. 7 (April 2012): 737–43. https://doi.org/10.1097/tp.0b013e3182466248.

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