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Paul Schroder, MD, PhD

House Staff
College/University: 
John Carroll University
Medical School: 
The University of Toledo College of Medicine

Clinical and Research Interests

  • Clinical interest: Abdominal organ transplantation
  • Research interest: Transplantation immunology

What were you looking for in a residency program?

A program that would provide me with a well-rounded surgical education, a place that provided opportunity for me to do additional research in the field of transplant immunology, and a place that had a strong abdominal organ transplant program that I could engage with and learn from prior to embarking on fellowship training.

What are the strengths of the Duke program?

The Surgery faculty are excellent and committed to resident learning. The opportunities for research in a multitude of fields related to surgery or surgical sciences is also a strength of the program.

What advice do you have for incoming interns?

The more promising your talents, the harder you will be pushed and the better surgeon you will become. The first year will go by faster than you think. Learn all that you can.

What do you like best about living in Durham and the Triangle?

The cost of living is very reasonable and there are an abundance of outdoor activities to do as well as a temperate climate all year round.

What do you like to do outside of Duke?

I enjoy paddleboarding, playing golf, and music.

Honors and Awards

  • June 2019 Oral Presentation at the American Transplant Congress 2019
    • "Dual targeting desensitization with Carfilzomib plus Lulizumab significantly prolongs kidney transplant survival in allosensitized nonhuman primates." Paul M. Schroder*, Robin Schmitz, Zachary Fitch, Brian Ezekian, Janghoon Yoon, John Yi, Ashley Choi, Andrew Barbas, Frank Leopardi, Bradley Collins, Jean Kwun, and Stuart J. Knechtle
  • June 2019 Poster Presentations at the American Transplant Congress 2019
    • "Novel in vitro germinal center culture system demonstrates more aggressive B cell to plasmablast differentiation in allosensitized nonhuman primates." Paul M. Schroder*, Janghoon Yoon, Robin Schmitz, Zachary Fitch, Jean Kwun, and Stuart J. Knechtle.
    • "Pre-transplant multidimensional flow cytometric analysis of kidney transplant recipients reveals novel immune signature of allograft rejection." Paul M. Schroder*, John S. Yi, Kent J. Weinhold, Cliburn Chan, Marybeth Joshi, Christy Walters, Jean Kwun, and Stuart J. Knechtle.
  • April 2019 *Poster of Distinction Presented at Duke Surgery Research Day 2019
    • "Dual targeting desensitization with Carfilzomib plus Lulizumab significantly prolongs kidney transplant survival in allosensitized nonhuman primates." Paul M. Schroder*, Robin Schmitz, Zachary Fitch, Brian Ezekian, Janghoon Yoon, John Yi, Ashley Choi, Andrew Barbas, Frank Leopardi, Bradley Collins, Jean Kwun, and Stuart J. Knechtle
  • December 2018 Poster Presentations at the Great Lakes Transplant Immunology Forum 2018
    • "Desensitization with Carfilzomib Plus CD28dAb Significantly Improves Kidney Transplant Survival in Allosensitized Nonhuman Primates." Paul M. Schroder*, Robin Schmitz, Zachary Fitch, Brian Ezekian, Janghoon Yoon, Andrew Barbas, Frank Leopardi, Bradley Collins, Jean Kwun, and Stuart J. Knechtle.
    •  "Generation of an Efficient and Reliable Method for Modeling the Germinal Center Reaction In Vitro." Paul M. Schroder*, Janghoon Yoon, Jean Kwun, and Stuart J. Knechtle.
  • June 2018 Poster Presentations at the American Transplant Congress 2018
    • "Humoral Immunity to CMV Remains Intact after Dual Targeting Desensitization in Allosensitized Nonhuman Primates." Paul Schroder*, Brian Ezekian, Frances Saccoccio, Janghoon Yoon, Maria Dennis, Kyle Freischlag, Jean Kwun, Sallie Permar, and Stuart Knechtle.
  • February 2018 Oral Presentation at the Academic Surgical Congress 2018
    • "Identifying Factors that Decrease Utilization of Adjuvant Chemotherapy in Stage III Colon Cancer." Paul M. Schroder*, Megan C. Turner, Brian Ezekian, Zhifei Sun, Mohamed A. Adam, Christopher R. Mantyh, and John Migaly.

Publications

Rees, Michael, Beata Mierzejewska, Paul Schroder, Caitlin Baum, Rene Duquesnoy, Marilyn Marrari, and Stanislaw Stepkowski. “EPITOPE SPREADING AND EPITOPE SHARING ARE INVOLVED IN ACUTE IGG1 ANTIBODY-MEDIATED REJECTION OF A KIDNEY TRANSPLANT WITH DISPARITY ONLY AT HLA-DP.” Transplant International 26 (November 1, 2013): 135–36.

Scholars@Duke

Khattar, Mithun, Paul Schroder, Caitlin Baum, Ronghai Deng, Wenhao Chen, and Stanislaw Stepkowski. “IL21 is a critical regulator of chronic/persistent autoimmune and allo-immune responses.” In Journal of Immunology, Vol. 190. AMER ASSOC IMMUNOLOGISTS, 2013.

Scholars@Duke

Guo, Zhiyong, Mithun Khattar, Paul M. Schroder, Yoshihiro Miyahara, Guohua Wang, Xiaoshung He, Wenhao Chen, and Stanislaw M. Stepkowski. “A dynamic dual role of IL-2 signaling in the two-step differentiation process of adaptive regulatory T cells.” Journal of Immunology (Baltimore, Md. : 1950) 190, no. 7 (April 2013): 3153–62. https://doi.org/10.4049/jimmunol.1200751.

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Guo, Z., Y. Miyahara, G. Wang, M. Khattar, P. Schroder, X. He, W. Chen, and S. Stepkowski. “A Dynamic Dual Role of IL-2 Signaling in the Two-Step Differentiation Process of Adaptive Regulatory T Cells.” In American Journal of Transplantation, 13:359–60. WILEY-BLACKWELL, 2013.

Scholars@Duke

Schroder, P., M. Khattar, R. Deng, C. Baum, B. Mierzejewska, and S. Stepkowski. “Antibody Targeting the TCR beta-Chain Selectively Abrogates Antigen-Specific T Cell Responses by Modulating T Cell Transcriptional Patterns.” In American Journal of Transplantation, 13:363–64. WILEY-BLACKWELL, 2013.

Scholars@Duke

Mierzejewska, B., P. Schroder, C. Baum, A. Blair, R. Duquesnoy, M. Marrari, M. Rees, and S. Stepkowski. “Epitope Spreading and Epitope Sharing Are Involved in Acute IgG1 Antibody-Mediated Rejection of a Kidney Transplant with Disparity Only at HLA-DP.” In American Journal of Transplantation, 13:318–318. WILEY-BLACKWELL, 2013.

Scholars@Duke

Schroder, P., M. Khattar, C. Baum, W. Chen, and S. Stepkowski. “IL21 Plays a Critical Role in Chronic Rejection but Not in Acute or Accelerated Allograft Rejection.” In American Journal of Transplantation, 13:552–552. WILEY-BLACKWELL, 2013.

Scholars@Duke

Baum, C., M. Khattar, R. Deng, B. Kahan, P. Schroder, T. Phan, L. Rutzky, and S. Stepkowski. “Locally-Delivered CD4(+)CD25(high)Foxp3(+) Regulatory T Cells Combined with Systemic KRP203 Therapy Induces Tolerance to Islet Allografts.” In American Journal of Transplantation, 13:55–55. WILEY-BLACKWELL, 2013.

Scholars@Duke

Khattar, Mithun, Ronghai Deng, Barry D. Kahan, Paul M. Schroder, Tammy Phan, Lynne P. Rutzky, and Stanislaw M. Stepkowski. “Novel sphingosine-1-phosphate receptor modulator KRP203 combined with locally delivered regulatory T cells induces permanent acceptance of pancreatic islet allografts.” Transplantation 95, no. 7 (April 2013): 919–27. https://doi.org/10.1097/tp.0b013e3182842396.

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