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Frank Hawkins Kenan Plastic Surgery Research Laboratories

Photo of Bruce Klitzman, PhD

Bruce Klitzman, PhD

Phone: 919-684-3929

Scientific Focus

Injectable biosensor detects oxygen levels in tissue
Injectable biosensor detects oxygen levels
in tissue

  • Improved function of implantable devices
  • Injectable, long-term, optical biosensors
  • Vascularization to optimize mass transport
  • Guiding the body to regenerate tissues and heal wounds

Our lab has expertise in biomaterials, microencapsulation, biosensors, wound healing, and the tissue response to implanted devices. We perform both pre-clinical and clinical studies. We created and ran the tissue viability service at Duke University Hospital and the Durham VA Hospital for 15 years, assessing the oxygenation of compromised limbs and correlating it with the healing potential of problem wounds.

Selected Achievements

  • Core Faculty, Duke Innovation & Entrepreneurship
  • Founder, MD/MEng dual degree program

Advanced Training

  • Certificate in Innovation & Entrepreneurship

Contact Us

Bruce Klitzman, PhD, Senior Director
Kenan Plastic Surgery Research Labs
Rm 479, Medical Sciences Research Building 1
203 Research Dr., Durham, NC 27710-3906
Phone: 919-684-3929                   

Latest Publications

Straube, Tobias L., Stewart Farling, Marc A. Deshusses, Bruce Klitzman, Ira M. Cheifetz, and Travis P. Vesel. “Intravascular Gas Exchange: Physiology, Literature Review, and Current Efforts.” Respir Care 67, no. 4 (April 2022): 480–93.

Full Text

Wu, Zi Jun, Mohamed M. Ibrahim, Amanda R. Sergesketter, Ryan M. Schweller, Brett T. Phillips, and Bruce Klitzman. “The Influence of Topical Vasodilator-Induced Pharmacologic Delay on Cutaneous Flap Viability and Vascular Remodeling.” Plast Reconstr Surg 149, no. 3 (March 1, 2022): 629–37.

Full Text

Ruppert, David S., Mahmoud M. Mohammed, Mohamed M. Ibrahim, Emilio O. Bachtiar, Kevin Erning, Kayvan Ansari, Jeffrey I. Everitt, et al. “Poly(lactide-co-ε-caprolactone) scaffold promotes equivalent tissue integration and supports skin grafts compared to a predicate collagen scaffold.” Wound Repair Regen 29, no. 6 (November 2021): 1035–50.

Full Text

Bottenus, N., T. Straube, S. Farling, T. Vesel, B. Klitzman, M. A. Deshusses, and I. M. Cheifetz. “Ultrasonic bubble detection and tracking using spatial coherence and motion modeling.” In Progress in Biomedical Optics and Imaging  Proceedings of Spie, Vol. 11602, 2021.

Full Text