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Stephanie N Langel, MS, PhD

Medical Instructor in the Department of Surgery

Education and Training

  • Post Doctoral Scholar, Duke Human Vaccine Institute, Duke University School of Medicine, 2019 - 2021
  • Ph.D., The Ohio State University College of Medicine, 2018
  • M.S., The Ohio State University College of Medicine, 2013
  • B.S., Virginia Tech, Carilion School of Medicine, 2011

Publications

Michael, Husheem, Francine C. Paim, Stephanie N. Langel, Ayako Miyazaki, David D. Fischer, Juliet Chepngeno, Joshua Amimo, et al. “Escherichia coli Nissle 1917 Enhances Innate and Adaptive Immune Responses in a Ciprofloxacin-Treated Defined-Microbiota Piglet Model of Human Rotavirus Infection.” Msphere 6, no. 2 (2021). https://doi.org/10.1128/mSphere.00074-21.

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Srivastava, V., L. Deblais, H. -. C. Huang, A. Miyazaki, S. Kandasamy, S. N. Langel, F. C. Paim, et al. “Reduced rotavirus vaccine efficacy in protein malnourished human-faecal-microbiota-transplanted gnotobiotic pig model is in part attributed to the gut microbiota.” Benef Microbes 11, no. 8 (December 2, 2020): 733–51. https://doi.org/10.3920/BM2019.0139.

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Singh, Tulika, Sarah M. Heston, Stephanie N. Langel, Maria Blasi, Jillian H. Hurst, Genevieve G. Fouda, Matthew S. Kelly, and Sallie R. Permar. “Lessons From COVID-19 in Children: Key Hypotheses to Guide Preventative and Therapeutic Strategies.” Clin Infect Dis 71, no. 8 (November 5, 2020): 2006–13. https://doi.org/10.1093/cid/ciaa547.

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Otero, Claire E., Stephanie N. Langel, Maria Blasi, and Sallie R. Permar. “Maternal antibody interference contributes to reduced rotavirus vaccine efficacy in developing countries.” Plos Pathog 16, no. 11 (November 2020): e1009010. https://doi.org/10.1371/journal.ppat.1009010.

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Langel, Stephanie N., Claire E. Otero, David R. Martinez, and Sallie R. Permar. “Maternal gatekeepers: How maternal antibody Fc characteristics influence passive transfer and infant protection.” Plos Pathog 16, no. 3 (March 2020): e1008303. https://doi.org/10.1371/journal.ppat.1008303.

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Langel, Stephanie N., Qiuhong Wang, Anastasia N. Vlasova, and Linda J. Saif. “Host Factors Affecting Generation of Immunity Against Porcine Epidemic Diarrhea Virus in Pregnant and Lactating Swine and Passive Protection of Neonates.” Pathogens 9, no. 2 (February 18, 2020). https://doi.org/10.3390/pathogens9020130.

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Michael, Husheem, Stephanie N. Langel, Ayako Miyazaki, Francine C. Paim, Juliet Chepngeno, Moyasar A. Alhamo, David D. Fischer, et al. “Malnutrition Decreases Antibody Secreting Cell Numbers Induced by an Oral Attenuated Human Rotavirus Vaccine in a Human Infant Fecal Microbiota Transplanted Gnotobiotic Pig Model.” Front Immunol 11 (2020): 196. https://doi.org/10.3389/fimmu.2020.00196.

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Langel, Stephanie N., Francine Chimelo Paim, Moyasar A. Alhamo, Kelly M. Lager, Anastasia N. Vlasova, and Linda J. Saif. “Oral vitamin A supplementation of porcine epidemic diarrhea virus infected gilts enhances IgA and lactogenic immune protection of nursing piglets.” Vet Res 50, no. 1 (November 29, 2019): 101. https://doi.org/10.1186/s13567-019-0719-y.

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Annamalai, Thavamathi, Zhongyan Lu, Kwonil Jung, Stephanie N. Langel, Christopher K. Tuggle, Jack C. M. Dekkers, Emily H. Waide, Sukumar Kandasamy, and Linda J. Saif. “Infectivity of GII.4 human norovirus does not differ between T-B-NK+ severe combined immunodeficiency (SCID) and non-SCID gnotobiotic pigs, implicating the role of NK cells in mediation of human norovirus infection.” Virus Res 267 (July 2, 2019): 21–25. https://doi.org/10.1016/j.virusres.2019.05.002.

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Lin, Chun-Ming, Shristi Ghimire, Yixuan Hou, Patricia Boley, Stephanie N. Langel, Anastasia N. Vlasova, Linda J. Saif, and Qiuhong Wang. “Pathogenicity and immunogenicity of attenuated porcine epidemic diarrhea virus PC22A strain in conventional weaned pigs.” Bmc Vet Res 15, no. 1 (January 11, 2019): 26. https://doi.org/10.1186/s12917-018-1756-x.

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