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Stephanie N Langel, MS, PhD

Medical Instructor in the Department of Surgery

Education and Training

  • Post Doctoral Scholar, Duke Human Vaccine Institute, Duke University School of Medicine, 2019 - 2021
  • Ph.D., The Ohio State University College of Medicine, 2018
  • M.S., The Ohio State University College of Medicine, 2013
  • B.S., Virginia Tech, Carilion School of Medicine, 2011

Publications

Langel, Stephanie N., Susan Johnson, Clarissa I. Martinez, Sarah N. Tedjakusuma, Nadine Peinovich, Emery G. Dora, Philip J. Kuehl, et al. “Adenovirus type 5 SARS-CoV-2 vaccines delivered orally or intranasally reduced disease severity and transmission in a hamster model.” Sci Transl Med, May 5, 2022, eabn6868. https://doi.org/10.1126/scitranslmed.abn6868.

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Langel, Stephanie N., Francine L. Kelly, David M. Brass, Andrew E. Nagler, Dylan Carmack, Joshua J. Tu, Tatianna Travieso, et al. “E-cigarette and food flavoring diacetyl alters airway cell morphology, inflammatory and antiviral response, and susceptibility to SARS-CoV-2.” Cell Death Discov 8, no. 1 (February 15, 2022): 64. https://doi.org/10.1038/s41420-022-00855-3.

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Michael, Husheem, Ayako Miyazaki, Stephanie N. Langel, Joshua O. Amimo, Maryssa K. Kick, Juliet Chepngeno, Francine C. Paim, et al. “Escherichia coli Nissle 1917 Enhances Efficacy of Oral Attenuated Human Rotavirus Vaccine in a Gnotobiotic Piglet Model.” Vaccines (Basel) 10, no. 1 (January 6, 2022). https://doi.org/10.3390/vaccines10010083.

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Goswami, Ria, Veronica S. Russell, Joshua J. Tu, Charlene Thomas, Philip Hughes, Francine Kelly, Stephanie N. Langel, et al. “Oral Hsp90 inhibitor SNX-5422 attenuates SARS-CoV-2 replication and dampens inflammation in airway cells.” Iscience 24, no. 12 (December 17, 2021): 103412. https://doi.org/10.1016/j.isci.2021.103412.

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Michael, Husheem, Francine C. Paim, Stephanie N. Langel, Ayako Miyazaki, David D. Fischer, Juliet Chepngeno, Joshua Amimo, et al. “Escherichia coli Nissle 1917 Enhances Innate and Adaptive Immune Responses in a Ciprofloxacin-Treated Defined-Microbiota Piglet Model of Human Rotavirus Infection.” Msphere 6, no. 2 (March 31, 2021). https://doi.org/10.1128/mSphere.00074-21.

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Michael, Husheem, Francine C. Paim, Ayako Miyazaki, Stephanie N. Langel, David D. Fischer, Juliet Chepngeno, Steven D. Goodman, Gireesh Rajashekara, Linda J. Saif, and Anastasia Nickolaevna Vlasova. “Escherichia coli Nissle 1917 administered as a dextranomar microsphere biofilm enhances immune responses against human rotavirus in a neonatal malnourished pig model colonized with human infant fecal microbiota.” Plos One 16, no. 2 (2021): e0246193. https://doi.org/10.1371/journal.pone.0246193.

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Michael, Husheem, Francine C. Paim, Stephanie N. Langel, Ayako Miyazaki, David D. Fischer, Juliet Chepngeno, Joshua Amimo, et al. “Escherichia coli Nissle 1917 Enhances Innate and Adaptive Immune Responses in a Ciprofloxacin-Treated Defined-Microbiota Piglet Model of Human Rotavirus Infection.” Msphere 6, no. 2 (2021). https://doi.org/10.1128/mSphere.00074-21.

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Srivastava, V., L. Deblais, H. -. C. Huang, A. Miyazaki, S. Kandasamy, S. N. Langel, F. C. Paim, et al. “Reduced rotavirus vaccine efficacy in protein malnourished human-faecal-microbiota-transplanted gnotobiotic pig model is in part attributed to the gut microbiota.” Benef Microbes 11, no. 8 (December 2, 2020): 733–51. https://doi.org/10.3920/BM2019.0139.

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Singh, Tulika, Sarah M. Heston, Stephanie N. Langel, Maria Blasi, Jillian H. Hurst, Genevieve G. Fouda, Matthew S. Kelly, and Sallie R. Permar. “Lessons From COVID-19 in Children: Key Hypotheses to Guide Preventative and Therapeutic Strategies.” Clin Infect Dis 71, no. 8 (November 5, 2020): 2006–13. https://doi.org/10.1093/cid/ciaa547.

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Otero, Claire E., Stephanie N. Langel, Maria Blasi, and Sallie R. Permar. “Maternal antibody interference contributes to reduced rotavirus vaccine efficacy in developing countries.” Plos Pathog 16, no. 11 (November 2020): e1009010. https://doi.org/10.1371/journal.ppat.1009010.

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