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Priyamvada Acharya, MS, PhD

Associate Professor in Surgery
Division: 
Surgical Sciences
Office: DUMC Box 103020, Durham, NC 27710
Campus Mail: DUMC LSRC Wing A, Room 6, DUMC Box 103020, Durham, NC 27710

Education and Training

  • Ph.D., Centre for Cellular and Molecular Biology (India), 2003
  • M.S., Jadavpur University (India), 1996
  • B.S., Jadavpur University (India), 1994

In the News

Selected Grants

Publications

Henderson, Rory, Robert J. Edwards, Katayoun Mansouri, Katarzyna Janowska, Victoria Stalls, Sophie M. C. Gobeil, Megan Kopp, et al. “Controlling the SARS-CoV-2 spike glycoprotein conformation.” Nat Struct Mol Biol 27, no. 10 (October 2020): 925–33. https://doi.org/10.1038/s41594-020-0479-4.

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Edwards, Robert J., Katayoun Mansouri, Victoria Stalls, Kartik Manne, Brian Watts, Rob Parks, Sophie M. C. Gobeil, et al. “Cold sensitivity of the SARS-CoV-2 spike ectodomain.” Biorxiv, July 13, 2020. https://doi.org/10.1101/2020.07.12.199588.

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Sempowski, Gregory D., Kevin O. Saunders, Priyamvada Acharya, Kevin J. Wiehe, and Barton F. Haynes. “Pandemic Preparedness: Developing Vaccines and Therapeutic Antibodies For COVID-19.” Cell 181, no. 7 (June 25, 2020): 1458–63. https://doi.org/10.1016/j.cell.2020.05.041.

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Henderson, Rory, Robert J. Edwards, Katayoun Mansouri, Katarzyna Janowska, Victoria Stalls, Sophie Gobeil, Megan Kopp, et al. “Controlling the SARS-CoV-2 Spike Glycoprotein Conformation.” Biorxiv, May 18, 2020. https://doi.org/10.1101/2020.05.18.102087.

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Henderson, Rory, Maolin Lu, Ye Zhou, Zekun Mu, Robert Parks, Qifeng Han, Allen L. Hsu, et al. “Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements.” Nat Commun 11, no. 1 (January 24, 2020): 520. https://doi.org/10.1038/s41467-019-14196-w.

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Setliff, Ian, Andrea R. Shiakolas, Kelsey A. Pilewski, Amyn A. Murji, Rutendo E. Mapengo, Katarzyna Janowska, Simone Richardson, et al. “High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity.” Cell 179, no. 7 (December 12, 2019): 1636-1646.e15. https://doi.org/10.1016/j.cell.2019.11.003.

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Saunders, Kevin O., Kevin Wiehe, Ming Tian, Priyamvada Acharya, Todd Bradley, S Munir Alam, Eden P. Go, et al. “Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.” Science 366, no. 6470 (December 6, 2019). https://doi.org/10.1126/science.aay7199.

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LaBranche, Celia C., Rory Henderson, Allen Hsu, Shay Behrens, Xuejun Chen, Tongqing Zhou, Kevin Wiehe, et al. “Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.” Plos Pathog 15, no. 12 (December 2019): e1008200. https://doi.org/10.1371/journal.ppat.1008200.

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LaBranche, Celia C., Rory Henderson, Allen Hsu, Shay Behrens, Xuejun Chen, Tongqing Zhou, Kevin Wiehe, et al. “Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.” Plos Pathog 15, no. 9 (September 2019): e1008026. https://doi.org/10.1371/journal.ppat.1008026.

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Kong, Rui, Hongying Duan, Zizhang Sheng, Kai Xu, Priyamvada Acharya, Xuejun Chen, Cheng Cheng, et al. “Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.” Cell 178, no. 3 (July 25, 2019): 567-584.e19. https://doi.org/10.1016/j.cell.2019.06.030.

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