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Priyamvada Acharya, MS, PhD

Associate Professor in Surgery
Division: 
Surgical Sciences
Office: DUMC Box 103020, Durham, NC 27710
Campus Mail: DUMC LSRC Wing A, Room 6, DUMC Box 103020, Durham, NC 27710

Education and Training

  • Ph.D., Centre for Cellular and Molecular Biology (India), 2003
  • M.S., Jadavpur University (India), 1996
  • B.S., Jadavpur University (India), 1994

In the News

Selected Grants

Publications

Sempowski, Gregory D., Kevin O. Saunders, Priyamvada Acharya, Kevin J. Wiehe, and Barton F. Haynes. “Pandemic Preparedness: Developing Vaccines and Therapeutic Antibodies For COVID-19.” Cell, May 27, 2020. https://doi.org/10.1016/j.cell.2020.05.041.

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Henderson, Rory, Maolin Lu, Ye Zhou, Zekun Mu, Robert Parks, Qifeng Han, Allen L. Hsu, et al. “Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements.” Nat Commun 11, no. 1 (January 24, 2020): 520. https://doi.org/10.1038/s41467-019-14196-w.

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Setliff, Ian, Andrea R. Shiakolas, Kelsey A. Pilewski, Amyn A. Murji, Rutendo E. Mapengo, Katarzyna Janowska, Simone Richardson, et al. “High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity.” Cell 179, no. 7 (December 12, 2019): 1636-1646.e15. https://doi.org/10.1016/j.cell.2019.11.003.

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Saunders, Kevin O., Kevin Wiehe, Ming Tian, Priyamvada Acharya, Todd Bradley, S Munir Alam, Eden P. Go, et al. “Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.” Science 366, no. 6470 (December 6, 2019). https://doi.org/10.1126/science.aay7199.

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LaBranche, Celia C., Rory Henderson, Allen Hsu, Shay Behrens, Xuejun Chen, Tongqing Zhou, Kevin Wiehe, et al. “Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.” Plos Pathog 15, no. 12 (December 2019): e1008200. https://doi.org/10.1371/journal.ppat.1008200.

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LaBranche, Celia C., Rory Henderson, Allen Hsu, Shay Behrens, Xuejun Chen, Tongqing Zhou, Kevin Wiehe, et al. “Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.” Plos Pathog 15, no. 9 (September 2019): e1008026. https://doi.org/10.1371/journal.ppat.1008026.

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Kong, Rui, Hongying Duan, Zizhang Sheng, Kai Xu, Priyamvada Acharya, Xuejun Chen, Cheng Cheng, et al. “Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.” Cell 178, no. 3 (July 25, 2019): 567-584.e19. https://doi.org/10.1016/j.cell.2019.06.030.

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Chuang, Gwo-Yu, Jing Zhou, Priyamvada Acharya, Reda Rawi, Chen-Hsiang Shen, Zizhang Sheng, Baoshan Zhang, et al. “Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition.” Structure 27, no. 1 (January 2, 2019): 196-206.e6. https://doi.org/10.1016/j.str.2018.10.007.

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Stewart-Jones, Guillaume B. E., Gwo-Yu Chuang, Kai Xu, Tongqing Zhou, Priyamvada Acharya, Yaroslav Tsybovsky, Li Ou, et al. “Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4.” Proc Natl Acad Sci U S A 115, no. 48 (November 27, 2018): 12265–70. https://doi.org/10.1073/pnas.1811980115.

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Behrens, Shay, Celia C. LaBranche, Tongqing Zhou, Kevin Wiehe, Mattia Bonsignori, Quentin J. Sattentau, Amanda Eaton, et al. “Germline-targeting and Reverse Engineering to Elicit CH235.12 Lineage bNAbs.” In Aids Research and Human Retroviruses, 34:116–116. MARY ANN LIEBERT, INC, 2018.

Scholars@Duke

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