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J Todd Purves, MD, PhD

Publications

Dunton, Cody L., J Todd Purves, Francis M. Hughes, Huixia Jin, and Jiro Nagatomi. “Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X4 in rat urothelial cells.” Int Urol Nephrol 50, no. 9 (September 2018): 1607–17. https://doi.org/10.1007/s11255-018-1948-0.

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Jiang, Ruiyang, Steven Wolf, Muhammad H. Alkazemi, Gina-Maria Pomann, J Todd Purves, John S. Wiener, and Jonathan C. Routh. “The evaluation of three comorbidity indices in predicting postoperative complications and readmissions in pediatric urology.” J Pediatr Urol 14, no. 3 (June 2018): 244.e1-244.e7. https://doi.org/10.1016/j.jpurol.2017.12.019.

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Leidig, Patrick, Francis Hughes, and J Todd Purves. “COMPONENTS OF URINARY STONES ACTIVATE THE NLRP3 INFLAMMASOME IN BLADDER UROTHELIUM.” In Journal of Urology, 199:E298–E298. ELSEVIER SCIENCE INC, 2018.

Scholars@Duke

Hughes, Francis, Brian Inouye, Eloise Stanton, Chloe Yun, Huixia Jin, and J. Purves. “NLRP3 INFLAMMASOME MEDIATED INFLAMMATION AND DENERVATION ARE CRITICAL PROCESSES IN THE DEVELOPMENT OF DIABETIC BLADDER DYSFUNCTION.” In Journal of Urology, 199:E501–E501. ELSEVIER SCIENCE INC, 2018.

Scholars@Duke

Hughes, Francis, Stephanie Sexton, Patrick Leidig, Huixia Jin, and J. Purves. “PHARMACOLOGICAL INHIBITION OF THE NLRP3 INFLAMMASOME PREVENTS BLADDER DECOMPENSATION IN A RAT MODEL OF CHRONIC BLADDER OUTLET OBSTRUCTION.” In Journal of Urology, 199:E112–13. ELSEVIER SCIENCE INC, 2018.

Scholars@Duke

Tejwani, Rohit, Ruiyang Jiang, Steven Wolf, Deanna W. Adkins, Brian J. Young, Muhammad Alkazemi, John S. Wiener, Gina-Maria Pomann, J Todd Purves, and Jonathan C. Routh. “Contemporary Demographic, Treatment, and Geographic Distribution Patterns for Disorders of Sex Development.” Clin Pediatr (Phila) 57, no. 3 (March 2018): 311–18. https://doi.org/10.1177/0009922817722013.

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Lütolf, Robin, Francis M. Hughes, Brian M. Inouye, Huixia Jin, Jennifer C. McMains, Elena S. Pak, Johanna L. Hannan, and J Todd Purves. “NLRP3/IL-1β mediates denervation during bladder outlet obstruction in rats.” Neurourol Urodyn 37, no. 3 (March 2018): 952–59. https://doi.org/10.1002/nau.23419.

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Inouye, Brian M., Francis M. Hughes, Stephanie J. Sexton, and J Todd Purves. “The Emerging Role of Inflammasomes as Central Mediators in Inflammatory Bladder Pathology.” Curr Urol 11, no. 2 (February 2018): 57–72. https://doi.org/10.1159/000447196.

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Inouye, Brian M., Francis M. Hughes, Huixia Jin, Robin Lütolf, Kunal C. Potnis, Jonathan C. Routh, Douglas C. Rouse, Wen-Chi Foo, and J Todd Purves. “Diabetic bladder dysfunction is associated with bladder inflammation triggered through hyperglycemia, not polyuria.” Res Rep Urol 10 (2018): 219–25. https://doi.org/10.2147/RRU.S177633.

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Hughes, Francis M., Stephanie J. Sexton, Huixia Jin, Vihasa Govada, and J Todd Purves. “Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β.” Am J Physiol Renal Physiol 313, no. 3 (September 1, 2017): F603–10. https://doi.org/10.1152/ajprenal.00128.2017.

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