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J Todd Purves, MD, PhD

Associate Professor of Surgery
Division: 
Urology
Faculty Lab: 
Duke University Urinary Dysfunction Laboratory
Program: 
Urology Residency Program

Education and Training

  • Pediatric Urology Fellow, Surgery/Urology, Johns Hopkins University School of Medicine, 2006 - 2008
  • Urology Resident, Surgery/Urology, University of Arizona, College of Medicine, 2002 - 2006
  • General Surgery Resident, Surgery, University of Arizona, College of Medicine, 2000 - 2002
  • M.D., University of Illinois College of Medicine, 2000
  • Ph.D., University of Illinois, Urbana-Champaign, 1998
  • A.B., Cornell University, 1991

Selected Grants

Publications

Hughes, Francis M., Armand Allkanjari, Michael R. Odom, Huixia Jin, and J Todd Purves. “Specialized pro-resolution mediators in the bladder: Receptor expression and recovery of bladder function from cystitis.” Exp Biol Med (Maywood) 247, no. 8 (April 2022): 700–711. https://doi.org/10.1177/15353702211067465.

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Dunton, Cody L., J Todd Purves, Francis M. Hughes, and Jiro Nagatomi. “BOO induces fibrosis and EMT in urothelial cells which can be recapitulated in vitro through elevated storage and voiding pressure cycles.” Int Urol Nephrol 53, no. 10 (October 2021): 2007–18. https://doi.org/10.1007/s11255-021-02942-3.

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Hughes, Taylor L., Kirsten L. Simmons, Rohit Tejwani, Karen D. Barton, John S. Wiener, J. Todd Purves, and Jonathan C. Routh. “Sexual Function and Dysfunction in Individuals with Spina Bifida: A Systematic Review.” Urology 156 (October 2021): 308–19. https://doi.org/10.1016/j.urology.2021.03.042.

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Hughes, Francis M., Shelby N. Harper, Brent D. Nosé, Armand Allkanjari, Michael T. Zheng, Huixia Jin, and J Todd Purves. “Specialized proresolution mediators in the bladder: annexin-A1 normalizes inflammation and bladder dysfunction during bladder outlet obstruction.” Am J Physiol Renal Physiol 321, no. 4 (October 1, 2021): F443–54. https://doi.org/10.1152/ajprenal.00205.2021.

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Johnston, Ashley W., Jonathan C. Routh, J Todd Purves, John S. Wiener, Angela Sinani, and Eda K. Holl. “Immune Expression in Children With Vesicoureteral Reflux: A Pilot Study.” Urology 148 (February 2021): 254–59. https://doi.org/10.1016/j.urology.2020.10.003.

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Dionise, Zachary R., Juan Marcos Gonzalez, Michael L. Garcia-Roig, Andrew J. Kirsch, Charles D. Scales, John S. Wiener, J Todd Purves, and Jonathan C. Routh. “Parental preferences for vesicoureteral reflux treatment: Profile case best-worst scaling.” J Pediatr Urol 17, no. 1 (February 2021): 86.e1-86.e9. https://doi.org/10.1016/j.jpurol.2020.11.020.

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Hughes, Francis, Shelby Harper, Armand Allkanjari, Brent Nose, Huixia Jin, and J Todd Purves. “THE ENDOGENOUS ANTI-INFLAMMATORY AGENT ANNEX-A1 INHIBITS ATP-INDUCED NLRP3 ACTIVATION IN VITRO AND NORMALIZES MOST BLADDER FUNCTIONS DURING BLADDER OUTLET OBSTRUCTION OR AFTER DE-OBSTRUCTION.” In Neurourology and Urodynamics, 40:S7–8, 2021.

Scholars@Duke

Chandrapal, Jason, Kirsten Simmons, J Todd Purves, John S. Wiener, and Jonathan C. Routh. “Association between race and in-hospital outcomes in children with spina bifida following inpatient urologic surgery.” J Pediatr Rehabil Med 14, no. 4 (2021): 597–604. https://doi.org/10.3233/PRM-200699.

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Hobbs, K Tyler, Madison Krischak, Rohit Tejwani, J Todd Purves, John S. Wiener, and Jonathan C. Routh. “The Importance of Early Diagnosis and Management of Pediatric Neurogenic Bladder Dysfunction.” Res Rep Urol 13 (2021): 647–57. https://doi.org/10.2147/RRU.S259307.

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Johnston, Ashley W., John S. Wiener, and J. Todd Purves. “Pediatric Neurogenic Bladder and Bowel Dysfunction: Will My Child Ever Be out of Diapers?” Eur Urol Focus 6, no. 5 (September 15, 2020): 838–67. https://doi.org/10.1016/j.euf.2020.01.003.

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