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J Todd Purves, MD, PhD

Associate Professor of Surgery
Division: 
Urology
Faculty Lab: 
Duke University Urinary Dysfunction Laboratory
Program: 
Urology Residency Program

Education and Training

  • Pediatric Urology Fellow, Surgery/Urology, Johns Hopkins University School of Medicine, 2006 - 2008
  • Urology Resident, Surgery/Urology, University of Arizona College of Medicine, 2002 - 2006
  • General Surgery Resident, Surgery, University of Arizona College of Medicine, 2000 - 2002
  • M.D., University of Illinois College of Medicine, 2000
  • Ph.D., University of Illinois -- Urbana-Champaign, 1998
  • A.B., Cornell University, 1991

Selected Grants

Publications

Inouye, Brian M., Ruiyang Jiang, M Hassan Alkazemi, Hsin-Hsiao S. Wang, Steven Wolf, Gina-Maria Pomann, Rohit Tejwani, John S. Wiener, J Todd Purves, and Jonathan C. Routh. “Hospital and ED charges for spina bifida care in the United States between 2006 and 2014: Over $2 billion annually..” Disabil Health J 12, no. 3 (July 2019): 431–36. https://doi.org/10.1016/j.dhjo.2019.01.007.

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Inouye, Brian M., Zachary R. Dionise, Ruiyang Jiang, Steven Wolf, Leigh Nicholl, Gina-Maria Pomann, John S. Wiener, J Todd Purves, and Jonathan C. Routh. “National Imaging and Antibiotic Practice Patterns in Children Presenting With Urinary Tract Infection to Community Practices: Little Impact From the American Academy of Pediatrics Guidelines?.” Clin Pediatr (Phila), June 5, 2019. https://doi.org/10.1177/0009922819853003.

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Dionise, Zachary R., Juan Marcos Gonzalez, Michael L. Garcia-Roig, Andrew J. Kirsch, Charles D. Scales, John S. Wiener, J Todd Purves, and Jonathan C. Routh. “Parental Preferences for Vesicoureteral Reflux Treatment: A Crowd-sourced, Best-worst Scaling Study..” Urology 128 (June 2019): 71–77. https://doi.org/10.1016/j.urology.2019.01.045.

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Kasotakis, George, Ekaterina Kintsurashvili, Manuel D. Galvan, Christopher Graham, J Todd Purves, Suresh Agarwal, David L. Corcoran, Bruce A. Sullenger, Scott M. Palmer, and Daniel G. Remick. “Histone Deacetylase 7 Inhibition in A Murine Model of Gram-Negative Pneumonia-Induced Acute Lung Injury..” Shock, May 2, 2019. https://doi.org/10.1097/SHK.0000000000001372.

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Sivaraman, Srikanth, Nicholas Amoroso, Xinzhu Gu, J Todd Purves, Francis M. Hughes, William R. Wagner, and Jiro Nagatomi. “Evaluation of Poly (Carbonate-Urethane) Urea (PCUU) Scaffolds for Urinary Bladder Tissue Engineering..” Ann Biomed Eng 47, no. 3 (March 2019): 891–901. https://doi.org/10.1007/s10439-018-02182-0.

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Hughes, Francis M., Nathan A. Hirshman, Brian M. Inouye, Huixia Jin, Eloise W. Stanton, Chloe E. Yun, Leah G. Davis, Jonathan C. Routh, and J Todd Purves. “NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation..” Diabetes 68, no. 2 (February 2019): 430–40. https://doi.org/10.2337/db18-0845.

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Hughes, Francis M., Stephanie J. Sexton, Patrick D. Ledig, Chloe E. Yun, Huixia Jin, and J Todd Purves. “Bladder decompensation and reduction in nerve density in a rat model of chronic bladder outlet obstruction are attenuated with the NLRP3 inhibitor glyburide..” Am J Physiol Renal Physiol 316, no. 1 (January 1, 2019): F113–20. https://doi.org/10.1152/ajprenal.00400.2018.

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Kelly, Maryellen S., Jonathan C. Routh, Leah G. Davis, J Todd Purves, John S. Wiener, and Matthew L. Maciejewski. “Lower Urinary Tract Symptoms in Older Children With and Without Diabetes Mellitus..” Clin Pediatr (Phila) 57, no. 13 (November 2018): 1576–81. https://doi.org/10.1177/0009922818796605.

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Inouye, Brian M., J Todd Purves, Jonathan C. Routh, Mahir Maruf, Daniel Friedlander, John Jayman, and John P. Gearhart. “How to close classic bladder exstrophy: Are subspecialty training and technique important?.” J Pediatr Urol 14, no. 5 (October 2018): 426.e1-426.e6. https://doi.org/10.1016/j.jpurol.2018.02.025.

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Dunton, Cody L., J Todd Purves, Francis M. Hughes, Huixia Jin, and Jiro Nagatomi. “Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X4 in rat urothelial cells..” Int Urol Nephrol 50, no. 9 (September 2018): 1607–17. https://doi.org/10.1007/s11255-018-1948-0.

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