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Gayathri R. Devi, PhD

Associate Director, Research Education
Associate Professor in Surgery
Associate Professor in Pathology
Office: 477 Med.Sci.Res.Bldg. (Msrb1), 2606 DUMC, Durham, NC 27710
Campus Mail: DUMC Box 2606 Med Ctr, Durham, NC 27710

Dr. Devi’s research interests include functional genomics, anti-cancer drug discovery and development, mechanisms of cancer cell signaling, tumor immunity and applications thereof for overcoming therapeutic resistance in cancer.

The lab has established prostate, inflammatory breast cancer and ovarian cellular and tumor models.

Education and Training

  • Ph.D., University of Nebraska College of Medicine, 1998

Publications

Arora, Vikram, Gayathri R. Devi, and Patrick L. Iversen. “Neutrally charged phosphorodiamidate morpholino antisense oligomers: uptake, efficacy and pharmacokinetics.” Curr Pharm Biotechnol 5, no. 5 (October 2004): 431–39. https://doi.org/10.2174/1389201043376706.

Full Text

Devi, G. R. “Preface.” Current Pharmaceutical Biotechnology, October 1, 2004.

Scholars@Duke

Ko, Yoo-Joung, Gayathri R. Devi, Carla A. London, Anthony Kayas, Muralimohan T. Reddy, Patrick L. Iversen, Glenn J. Bubley, and Steven P. Balk. “Androgen receptor down-regulation in prostate cancer with phosphorodiamidate morpholino antisense oligomers.” J Urol 172, no. 3 (September 2004): 1140–44. https://doi.org/10.1097/01.ju.0000134698.87862.e6.

Full Text

Amantana, Adams, Carla A. London, Patrick L. Iversen, and Gayathri R. Devi. “X-linked inhibitor of apoptosis protein inhibition induces apoptosis and enhances chemotherapy sensitivity in human prostate cancer cells.” Mol Cancer Ther 3, no. 6 (June 2004): 699–707.

Scholars@Duke

Ko, Y. J., G. R. Devi, C. A. London, A. Kayas, M. T. Reddy, P. L. Iverson, G. J. Bubley, and S. P. Balk. “Androgen receptor downregulation in prostate cancer with phosphorodiamidate morpholino antisense oligomers.” In Clinical Cancer Research, 9:6084S-6084S. AMER ASSOC CANCER RESEARCH, 2003.

Scholars@Duke

London, Carla A., Harmanjatinder S. Sekhon, Vikram Arora, David A. Stein, Patrick L. Iversen, and Gayathri R. Devi. “A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity.” Cancer Gene Ther 10, no. 11 (November 2003): 823–32. https://doi.org/10.1038/sj.cgt.7700642.

Full Text

Iversen, Patrick L., Vikram Arora, A. J. Acker, David H. Mason, and Gayathri R. Devi. “Efficacy of antisense morpholino oligomer targeted to c-myc in prostate cancer xenograft murine model and a Phase I safety study in humans.” Clin Cancer Res 9, no. 7 (July 2003): 2510–19.

Scholars@Duke

Devi, G. “Gene Therapy of Cancer - 11th International Conference: 12-14 December 2002, San Diego, USA.” In Idrugs, 6:104–6, 2003.

Scholars@Duke

London, C. A., D. C. Knapp, Y. J. Ko, S. Balk, M. DeSouza, D. H. Farrell, P. L. Iversen, and G. R. Devi. “In vivo efficacy of phosphorodiamidate morpholino-based antisense oligomers in tumor and angiogenesis models.” In Cancer Gene Therapy, 10:S3–4. NATURE PUBLISHING GROUP, 2003.

Scholars@Duke

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