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Gayathri R. Devi, PhD

Associate Director, Research Education
Associate Professor in Surgery
Associate Professor in Pathology
Office: 477 Med.Sci.Res.Bldg. (Msrb1), 2606 DUMC, Durham, NC 27710
Campus Mail: DUMC Box 2606 Med Ctr, Durham, NC 27710

Dr. Devi’s research interests include functional genomics, anti-cancer drug discovery and development, mechanisms of cancer cell signaling, tumor immunity and applications thereof for overcoming therapeutic resistance in cancer.

The lab has established prostate, inflammatory breast cancer and ovarian cellular and tumor models.

Education and Training

  • Ph.D., University of Nebraska College of Medicine, 1998

Publications

Shammas, R. L., A. M. Fales, B. M. Crawford, S. T. Hollenbeck, T. Vo-Dinh, and G. R. Devi. “Abstract P3-16-02: Nanotheranostics using plasmonic gold nanostars to target inflammatory breast cancer cells and tumor emboli.” In Poster Session Abstracts. American Association for Cancer Research, 2017. https://doi.org/10.1158/1538-7445.sabcs16-p3-16-02.

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Devi, Gayathri R., Eun-Sil Shelley Hwang, John Stewart, Michael A. Morse, and Steven Van Laere. “Abstract B44: Immune pathway dysregulations in inflammatory breast cancer health disparity.” In Cell, Molecular, and Tumor Biology. American Association for Cancer Research, 2017. https://doi.org/10.1158/1538-7755.disp16-b44.

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Crawford, Bridget M., Ronnie L. Shammas, Andrew M. Fales, David A. Brown, Scott T. Hollenbeck, Tuan Vo-Dinh, and Gayathri R. Devi. “Photothermal ablation of inflammatory breast cancer tumor emboli using plasmonic gold nanostars.” Int J Nanomedicine 12 (2017): 6259–72. https://doi.org/10.2147/IJN.S141164.

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Woodward, Wendy A., Massimo Cristofanilli, Sofia D. Merajver, Steven Van Laere, Lajos Pusztai, Francois Bertucci, Fedor Berditchevski, et al. “Scientific Summary from the Morgan Welch MD Anderson Cancer Center Inflammatory Breast Cancer (IBC) Program 10th Anniversary Conference.” J Cancer 8, no. 17 (2017): 3607–14. https://doi.org/10.7150/jca.21200.

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Evans, Myron K., Joseph Geradts, Courtney Edwards, Arianna Price, Arjun J. Arora, Amy J. Aldrich, Adrian Ramirez, et al. “Abstract LB-015: XIAP induction by the MAPK-eIF4G1 pathway drives NFκB activation in inflammatory breast cancer growth and therapeutic resistance.” In Molecular and Cellular Biology, Genetics. American Association for Cancer Research, 2016. https://doi.org/10.1158/1538-7445.am2016-lb-015.

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Evans, M. K., S. J. Sauer, S. Nath, T. J. Robinson, M. A. Morse, and G. R. Devi. “X-linked inhibitor of apoptosis protein mediates tumor cell resistance to antibody-dependent cellular cytotoxicity.” Cell Death Dis 7 (January 28, 2016): e2073. https://doi.org/10.1038/cddis.2015.412.

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Allensworth, Jennifer L., Myron K. Evans, François Bertucci, Amy J. Aldrich, Richard A. Festa, Pascal Finetti, Naoto T. Ueno, et al. “Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer.” Mol Oncol 9, no. 6 (June 2015): 1155–68. https://doi.org/10.1016/j.molonc.2015.02.007.

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Evans, Myron K., Scott J. Sauer, Amy J. Aldrich, Joseph Geradts, Peter Vermeulen, Luc Dirix, Steven Van Laere, and Gayathri R. Devi. “Abstract P6-14-05: A novel link between anti-apoptotic signaling, NFκB, and SMAD7 in IBC pathobiology.” In Poster Session Abstracts. American Association for Cancer Research, 2015. https://doi.org/10.1158/1538-7445.sabcs14-p6-14-05.

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