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Aravind Asokan, PhD

Director of Gene Therapy
Professor in Surgery
Professor of Molecular Genetics and Microbiology
Campus Mail: DUMC 3 Genome Court, Msrb3, 5148, Box 2653, Duke Surgery, Durham, NC 27710

Synthetic Virology & Gene Therapy

Education and Training

  • Ph.D., University of North Carolina - Chapel Hill, 2004

Publications

Huang, Lin-Ya, Robert Ng, Edward B. Miller, Robert McKenna, Aravind Asokan, and Mavis Agbandje-McKenna. “Characterizing Essential Receptor Binding Residues for AAV1.” In Molecular Therapy, 22:S2–S2. NATURE PUBLISHING GROUP, 2014.

Scholars@Duke

Tseng, Yu-Shan, Kim Van Vliet, Matias Kaplan, J Kennon Smith, Lavanya Rao, Robert McKenna, Barry J. Byrne, Sergei Zolotukhin, Aravind Asokan, and Mavis Agbandje-McKenna. “Mapping the Antigenic Structure of Adeno-Associated Virus Serotypes 8 and 9.” In Molecular Therapy, 22:S1–S1. NATURE PUBLISHING GROUP, 2014.

Scholars@Duke

Simpson, Elizabeth M., Charles N. de Leeuw, Siu Ling Lam, Andrea J. Korecki, Russell J. Bonaguro, Kaelan Wong, Michelle Zhou, et al. “Regional-CNS MiniPromoters for AAV Are Identified in a High Through-Put Pipeline.” In Molecular Therapy, 22:S112–S112. NATURE PUBLISHING GROUP, 2014.

Scholars@Duke

Shen, Shen, Andrew N. Troupes, Nagesh Pulicherla, and Aravind Asokan. “Multiple roles for sialylated glycans in determining the cardiopulmonary tropism of adeno-associated virus 4.” J Virol 87, no. 24 (December 2013): 13206–13. https://doi.org/10.1128/JVI.02109-13.

Full Text

Shen, Shen, Eric D. Horowitz, Andrew N. Troupes, Sarah M. Brown, Nagesh Pulicherla, Richard J. Samulski, Mavis Agbandje-McKenna, and Aravind Asokan. “Engraftment of a galactose receptor footprint onto adeno-associated viral capsids improves transduction efficiency.” J Biol Chem 288, no. 40 (October 4, 2013): 28814–23. https://doi.org/10.1074/jbc.M113.482380.

Full Text

Shen, Shen, and Aravind Asokan. “Integrins Play a Pivotal Role in Transvascular Transport and Tissue Uptake of AAV9 In Vivo.” In Molecular Therapy, 21:S30–S30. NATURE PUBLISHING GROUP, 2013.

Scholars@Duke

Murlidharan, Giridhar, Laura Sommerville, Troy Ghashghaei, and Aravind Asokan. “Re-Engineering Capsid-Glycan Interactions Expands the CNS Transduction Profile of AAV Serotype 4.” In Molecular Therapy, 21:S1–S1. NATURE PUBLISHING GROUP, 2013.

Scholars@Duke

Shen, Shen, Andrew Troupes, Nagesh Pulicherla, and Aravind Asokan. “Sialic Acids and Erythrocyte Interactions Are Critical Determinants of Cardiopulmonary Tropism Displayed by AAV Serotype 4.” In Molecular Therapy, 21:S31–S31. NATURE PUBLISHING GROUP, 2013.

Scholars@Duke

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