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Aravind Asokan, PhD

Director of Gene Therapy
Professor in Surgery
Professor of Molecular Genetics and Microbiology
Campus Mail: DUMC 3 Genome Court, Msrb3, 5148, Box 2653, Duke Surgery, Durham, NC 27710

Synthetic Virology & Gene Therapy

Education and Training

  • Ph.D., University of North Carolina - Chapel Hill, 2004

Publications

Asokan, Aravind, and Moo J. Cho. “Cytosolic delivery of macromolecules 4. Head group-dependent membrane permeabilization by pH-sensitive detergents.” J Control Release 106, no. 1–2 (August 18, 2005): 146–53. https://doi.org/10.1016/j.jconrel.2005.04.010.

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Asokan, Aravind, and Moo J. Cho. “Cytosolic delivery of macromolecules. 3. Synthesis and characterization of acid-sensitive bis-detergents.” In Bioconjug Chem, 15:1166–73, 2004. https://doi.org/10.1021/bc049880n.

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Asokan, Aravind, and Moo J. Cho. “Cytosolic delivery of macromolecules. II. Mechanistic studies with pH-sensitive morpholine lipids.” Biochim Biophys Acta 1611, no. 1–2 (April 1, 2003): 151–60. https://doi.org/10.1016/s0005-2736(03)00050-6.

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Chen, Feng-Jing, Aravind Asokan, and Moo J. Cho. “Cytosolic delivery of macromolecules: I. Synthesis and characterization of pH-sensitive acyloxyalkylimidazoles.” Biochim Biophys Acta 1611, no. 1–2 (April 1, 2003): 140–50. https://doi.org/10.1016/s0005-2736(03)00049-x.

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Asokan, Aravind, and Moo J. Cho. “Exploitation of intracellular pH gradients in the cellular delivery of macromolecules.” J Pharm Sci 91, no. 4 (April 2002): 903–13. https://doi.org/10.1002/jps.10095.

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