Synthetic Virology & Gene Therapy
Albright, BH, Simon, KE, Pillai, M, Devlin, G, and Asokan, A. "Modulation of sialic acid dependence influences the CNS transduction profile of adeno-associated viruses." Journal of Virology (March 20, 2019).
Nelson, CE, Wu, Y, Gemberling, MP, Oliver, ML, Waller, MA, Bohning, JD, Robinson-Hamm, JN, Bulaklak, K, Castellanos Rivera, RM, Collier, JH, Asokan, A, and Gersbach, CA. "Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy." Nature Medicine 25, no. 3 (March 2019): 427-432.
Mestre, H, Hablitz, LM, Xavier, AL, Feng, W, Zou, W, Pu, T, Monai, H, Murlidharan, G, Castellanos Rivera, RM, Simon, MJ, Pike, MM, Plá, V, Du, T, Kress, BT, Wang, X, Plog, BA, Thrane, AS, Lundgaard, I, Abe, Y, Yasui, M, Thomas, JH, Xiao, M, Hirase, H, Asokan, A, Iliff, JJ, and Nedergaard, M. "Aquaporin-4-dependent glymphatic solute transport in the rodent brain." Elife 7 (December 18, 2018).
Meganck, RM, Borchardt, EK, Castellanos Rivera, RM, Scalabrino, ML, Wilusz, JE, Marzluff, WF, and Asokan, A. "Tissue-Dependent Expression and Translation of Circular RNAs with Recombinant AAV Vectors In Vivo." Molecular Therapy. Nucleic Acids 13 (December 2018): 89-98.
Castle, MJ, Cheng, Y, Asokan, A, and Tuszynski, MH. "Physical positioning markedly enhances brain transduction after intrathecal AAV9 infusion." Science Advances 4, no. 11 (November 14, 2018): eaau9859-null.
Burwitz, B, Wettengel, J, Muck-Hausl, M, Hammond, K, Ringelhan, M, Ko, C, Reed, J, Norris, R, Park, B, Moller-Tank, S, Esser, K, Greenel, J, Wu, H, Abdulhaqq, S, Webb, G, Sutton, W, Klug, A, Swanson, T, Legasse, A, Asokan, A, Haigwood, N, Protzer', U, and Sacha, J. "A new HIV/HBV co-infection model: hepatocytic expression of human sodium taurocholate cotransporting polypeptide (NTCP) Enables Hepatitis B Virus Infection of Macaques.": WILEY, October 1, 2018.
Burwitz, B, Wettengel, J, Muck-Hausl, M, Hammond, K, Ringelhan, M, Ko, C, Reed, J, Norris, R, Park, B, Moller-Tank, S, Esser, K, Greenel, J, Wu, H, Abdulhaqq, S, Webb, G, Sutton, W, Klug, A, Swanson, T, Legasse, A, Asokan, A, Haigwood, N, Protzer', U, and Sacha, J. "A new HIV/HBV co-infection model: hepatocytic expression of human sodium taurocholate cotransporting polypeptide (NTCP) Enables Hepatitis B Virus Infection of Macaques.": WILEY, October 1, 2018.
Tse, LV, Moller-Tank, S, Meganck, RM, and Asokan, A. "Mapping and Engineering Functional Domains of the Assembly-Activating Protein of Adeno-associated Viruses." Journal of Virology 92, no. 14 (July 2018).
Albright, BH, Storey, C, Devlin, G, Agbandje-McKenna, M, and Asokan, A. "Capsid-Glycan Receptor Interactions Influence AAV Transport across the Blood-Brain Barrier." 21st Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT). Chicago, IL. May 16, 2018 - May 19, 2018.: CELL PRESS, May 1, 2018.
Robinson-Hamm, JN, Nelson, CE, Gemberling, M, Gough, V, Rivera, RMC, Aartsma-Rus, A, Asokan, A, and Gersbach, CA. "Dystrophin Restoration in a Humanized Mouse Model of Duchenne Muscular Dystrophy by Gene Editing with S. Aureus Cas9." 21st Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT). Chicago, IL. May 16, 2018 - May 19, 2018.: CELL PRESS, May 1, 2018.