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Amy Claudine Hobeika, PhD

Assistant Professor in Surgery
Division: 
Surgical Sciences
Faculty Lab: 
Center for Applied Therapeutics
Office: 404A MSRB 1, Research Dr, Durham, NC 27710
Campus Mail: DUMC Box 2606 Med Ctr, Durham, NC 27710

Education and Training

  • Post doctoral Associate, University of Florida, 1997 - 1999
  • Teaching Assistant, University of Florida, 1993 - 1996
  • Laboratory Technician, University of Florida, 1993 - 1996
  • Ph.D., University of Florida, 1997

Selected Grants

Publications

Mosca, P. J., A. C. Hobeika, T. M. Clay, S. K. Nair, E. K. Thomas, M. A. Morse, and H. K. Lyerly. “A subset of human monocyte-derived dendritic cells expresses high levels of interleukin-12 in response to combined CD40 ligand and interferon-gamma treatment.” Blood 96, no. 10 (November 15, 2000): 3499–3504.

Scholars@Duke

Kominsky, S. L., A. C. Hobeika, F. A. Lake, B. A. Torres, and H. M. Johnson. “Down-regulation of neu/HER-2 by interferon-gamma in prostate cancer cells.” Cancer Res 60, no. 14 (July 15, 2000): 3904–8.

Scholars@Duke

Hobeika, A. C., W. Etienne, B. A. Torres, H. M. Johnson, and P. S. Subramaniam. “IFN-gamma induction of p21(WAF1) is required for cell cycle inhibition and suppression of apoptosis.” J Interferon Cytokine Res 19, no. 12 (December 1999): 1351–61. https://doi.org/10.1089/107999099312812.

Full Text

Hobeika, A. C., W. Etienne, H. M. Johnson, and P. S. Subramaniam. “IFN gamma induction of p21(WAF1) is required for cell cycle inhibition and suppression of apoptosis.” In Faseb Journal, 13:A610–A610. FEDERATION AMER SOC EXP BIOL, 1999.

Scholars@Duke

Kominsky, S., H. M. Johnson, G. Bryan, T. Tanabe, A. C. Hobeika, P. S. Subramaniam, and B. Torres. “IFNgamma inhibition of cell growth in glioblastomas correlates with increased levels of the cyclin dependent kinase inhibitor p21WAF1/CIP1.” Oncogene 17, no. 23 (December 10, 1998): 2973–79. https://doi.org/10.1038/sj.onc.1202217.

Full Text

Hobeika, A. C., W. Etienne, P. E. Cruz, P. S. Subramaniam, and H. M. Johnson. “IFNgamma induction of p21WAF1 in prostate cancer cells: role in cell cycle, alteration of phenotype and invasive potential.” Int J Cancer 77, no. 1 (July 3, 1998): 138–45. https://doi.org/10.1002/(sici)1097-0215(19980703)77:1<138::aid-ijc21>3.0.co;2-9.

Full Text

Subramaniam, P. S., P. E. Cruz, A. C. Hobeika, and H. M. Johnson. “Type I interferon induction of the Cdk-inhibitor p21WAF1 is accompanied by ordered G1 arrest, differentiation and apoptosis of the Daudi B-cell line.” Oncogene 16, no. 14 (April 1998): 1885–90. https://doi.org/10.1038/sj.onc.1201712.

Full Text

Hobeika, A. C., W. Etienne, P. E. Cruz, P. S. Subramaniam, and H. M. Johnson. “IFN gamma induction of p21(WAF1) in prostate cancer cells: Role in cell cycle and cell phenotype.” In Faseb Journal, 12:A283–A283. FEDERATION AMER SOC EXP BIOL, 1998.

Scholars@Duke

Hobeika, A. C., W. Etienne, P. E. Cruz, P. S. Subramaniam, and H. M. Johnson. “IFNγ induction of P21WAF1 in prostate cancer cells: Role in cell cycle and cell phenotype.” In Faseb Journal, Vol. 12, 1998.

Scholars@Duke

Kominsky, S., B. Torres, G. Bryan, A. Hobeika, T. Tanabe, P. Subramaniam, and H. M. Johnson. “IFNγ inhibition of cell growth in glioblastomas is accompanied by induction of the cyclin dependent kinase inhibitor p21.” In Faseb Journal, Vol. 12, 1998.

Scholars@Duke

Pages