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Rachel Adams Greenup, MD, MPH

Associate Professor of Surgery
Associate Professor in Population Health Sciences
Campus Mail: DUMC DUMC 3513, Durham, NC 27710

Dr. Greenup is an Associate Professor of Surgery and Population Health Sciences at the Duke School of Medicine and Duke Cancer Institute. She is the founder and co-director of the Duke Breast Cancer Outcomes Research Group, and Core Faculty for the Duke Margolis Center for Health Policy.

She earned her undergraduate degrees in Zoology and Psychology at the University of Wisconsin, where she later completed a Masters in Public Health. She attended the Medical College of Wisconsin for Medical School and General Surgery Residency, and went on to complete a Breast Surgical Oncology Fellowship at the Massachusetts General Hospital, Dana Farber Cancer Institute, and Brigham and Women’s Hospital. In 2016, she received the National Institutes of Health Building Interdisciplinary Research Careers in Women’s Health (BIRCWH) Award to evaluate how financial costs and burden relate to preference-sensitive decisions for breast cancer surgery. In 2017, she was named the American College of Surgeons & American Society of Breast Surgeons Health Policy Scholar. More broadly, her research focuses on aligning patient-centered care with high quality, lower cost treatment.

Dr. Greenup serves on several national committees, including the Alliance in Clinical Oncology Ethics and Value Committees, the American College of Surgeons Cancer Care Delivery Task Force, the American Society of Breast Surgeons Legislative Committee, and the Editorial Board for the Annals of Surgical Oncology. 

Education and Training

  • Breast Surgical Oncology Fellow, Massachusetts General Hospital, 2011 - 2012
  • Internship/General Surgery Residency, Medical College of Wisconsin, 2004 - 2011
  • M.P.H., University of Wisconsin - Madison, 2009
  • M.D., Medical College of Wisconsin, 2004

Publications

Plichta, Jennifer K., Samantha M. Thomas, Amanda R. Sergesketter, Rachel A. Greenup, Laura H. Rosenberger, Oluwadamilola M. Fayanju, Gretchen Kimmick, Jeremy Force, Terry Hyslop, and E Shelley Hwang. “A Novel Staging System for De Novo Metastatic Breast Cancer Refines Prognostic Estimates.” Ann Surg, July 9, 2020. https://doi.org/10.1097/SLA.0000000000004231.

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Ong, Cecilia T., Yi Ren, Samantha M. Thomas, Ilona Stashko, Terry Hyslop, Gretchen Kimmick, Rachel C. Blitzblau, E Shelley Hwang, Lars J. Grimm, and Rachel A. Greenup. “Overall health at diagnosis predicts the risk of complications within the first year after breast cancer diagnosis.” In Breast Cancer Res Treat, 182:439–49, 2020. https://doi.org/10.1007/s10549-020-05700-8.

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Nichols, Brandon S., Erika Chelales, Roujia Wang, Amanda Schulman, Jennifer Gallagher, Rachel A. Greenup, Joseph Geradts, et al. “Quantitative assessment of distant recurrence risk in early stage breast cancer using a nonlinear combination of pathological, clinical and imaging variables.” J Biophotonics, June 23, 2020, e201960235. https://doi.org/10.1002/jbio.201960235.

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Spring, Laura M., Geoffrey Fell, Andrea Arfe, Chandni Sharma, Rachel Greenup, Kerry L. Reynolds, Barbara L. Smith, et al. “Pathologic Complete Response after Neoadjuvant Chemotherapy and Impact on Breast Cancer Recurrence and Survival: A Comprehensive Meta-analysis.” Clin Cancer Res 26, no. 12 (June 15, 2020): 2838–48. https://doi.org/10.1158/1078-0432.CCR-19-3492.

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Offodile, Anaeze C., E Shelley Hwang, and Rachel Adams Greenup. “Contralateral Prophylactic Mastectomy in the Era of Financial Toxicity: An Additional Point for Concern?” Ann Surg 271, no. 5 (May 2020): 817–18. https://doi.org/10.1097/SLA.0000000000003629.

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Fayanju, Oluwadamilola M., Yi Ren, Samantha M. Thomas, Rachel A. Greenup, Terry Hyslop, E Shelley Hwang, and John H. Stewart. “A Case-Control Study Examining Disparities in Clinical Trial Participation Among Breast Surgical Oncology Patients.” Jnci Cancer Spectr 4, no. 2 (April 2020): pkz103. https://doi.org/10.1093/jncics/pkz103.

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Sammons, Sarah, Yi Ren, Jeremy Force, Oluwadamilola M. Fayanju, Laura H. Rosenberger, Jennifer K. Plichta, Gretchen Kimmick, et al. “Abstract P3-08-10: Characterization of oncotype DX recurrence score and chemotherapy utilization patterns in young women (≤40) with early stage ER+/HER-, lymph node negative breast cancer.” In Poster Session Abstracts. American Association for Cancer Research, 2020. https://doi.org/10.1158/1538-7445.sabcs19-p3-08-10.

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Rosenberger, Laura H., Yi Ren, Samantha M. Thomas, Rachel A. Greenup, Oluwadamilola M. Fayanju, E Shelley Hwang, and Jennifer K. Plichta. “Axillary lymph node dissection in node-positive breast cancer: are ten nodes adequate and when is enough, enough?” In Breast Cancer Res Treat, 179:661–70, 2020. https://doi.org/10.1007/s10549-019-05500-9.

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Fayanju, Oluwadamilola M., Yi Ren, Gita Suneja, Samantha M. Thomas, Rachel A. Greenup, Jennifer K. Plichta, Laura H. Rosenberger, Jeremy Force, Terry Hyslop, and E Shelley Hwang. “Nodal Response to Neoadjuvant Chemotherapy Predicts Receipt of Radiation Therapy After Breast Cancer Diagnosis.” Int J Radiat Oncol Biol Phys 106, no. 2 (February 1, 2020): 377–89. https://doi.org/10.1016/j.ijrobp.2019.10.039.

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Akushevich, Igor, Arseniy P. Yashkin, Rachel A. Greenup, and E Shelley Hwang. “A medicare-based comparative mortality analysis of active surveillance in older women with DCIS.” Npj Breast Cancer 6 (2020): 57. https://doi.org/10.1038/s41523-020-00199-0.

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