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John S Yi, PhD

Assistant Professor of Surgery
Office: 915 S. Lasalle Street, 204 Sorf (Bldg. 41) Box 2926, Durham, NC 27710

I am an immunologist, with a focus to characterize the immune system in response to infectious and non-infectious diseases including cancer, HIV, autoimmune disease, and transplantation. My goals are to identify novel biomarkers/immune signatures that clinicians can utilize to diagnosis, predict disease outcomes, and determine patients' response to treatment. 

Education and Training

  • Ph.D., University of Alabama at Birmingham, 2010

Publications

Yi, JS, Guptill, JT, Stathopoulos, P, Nowak, RJ, and O'Connor, KC. "B cells in the pathophysiology of myasthenia gravis." Muscle & nerve 57, no. 2 (February 2018): 172-184.

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Reap, EA, Suryadevara, CM, Batich, KA, Sanchez-Perez, L, Archer, GE, Schmittling, RJ, Norberg, PK, Herndon, JE, Healy, P, Congdon, KL, Gedeon, PC, Campbell, OC, Swartz, AM, Riccione, KA, Yi, JS, Hossain-Ibrahim, MK, Saraswathula, A, Nair, SK, Dunn-Pirio, AM, Broome, TM, Weinhold, KJ, Desjardins, A, Vlahovic, G, McLendon, RE, Friedman, AH, Friedman, HS, Bigner, DD, Fecci, PE, Mitchell, DA, and Sampson, JH. "Dendritic Cells Enhance Polyfunctionality of Adoptively Transferred T Cells That Target Cytomegalovirus in Glioblastoma." Cancer research 78, no. 1 (January 2018): 256-264.

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Yi, JS, Ready, N, Healy, P, Dumbauld, C, Osborne, R, Berry, M, Shoemaker, D, Clarke, J, Crawford, J, Tong, B, Harpole, D, D'Amico, TA, McSherry, F, Dunphy, F, McCall, SJ, Christensen, JD, Wang, X, and Weinhold, KJ. "Immune Activation in Early-Stage Non-Small Cell Lung Cancer Patients Receiving Neoadjuvant Chemotherapy Plus Ipilimumab." Clinical cancer research : an official journal of the American Association for Cancer Research 23, no. 24 (December 2017): 7474-7482.

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Kwun, J, Burghuber, C, Manook, M, Ezekian, B, Park, J, Yoon, J, Yi, JS, Iwakoshi, N, Gibby, A, Hong, JJ, Farris, AB, Kirk, AD, and Knechtle, SJ. "Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates." Blood advances 1, no. 24 (November 2017): 2115-2119.

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Yi, JS, Russo, MA, Massey, JM, Juel, V, Hobson-Webb, LD, Gable, K, Raja, SM, Balderson, K, Weinhold, KJ, and Guptill, JT. "B10 Cell Frequencies and Suppressive Capacity in Myasthenia Gravis Are Associated with Disease Severity." Frontiers in Neurology 8 (January 2017): 34-.

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Guptill, JT, Juel, VC, Massey, JM, Anderson, AC, Chopra, M, Yi, JS, Esfandiari, E, Buchanan, T, Smith, B, Atherfold, P, Jones, E, and Howard, JF. "Effect of therapeutic plasma exchange on immunoglobulins in myasthenia gravis." Autoimmunity 49, no. 7 (November 2016): 472-479.

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Yi, JS, Russo, MA, Weinhold, KJ, and Guptill, JT. "Adaptive immune response to therapy in hmgcr autoantibody myopathy." Muscle & nerve 53, no. 2 (February 2016): 313-317.

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Abedini-Nassab, R, Joh, DY, Van Heest, MA, Yi, JS, Baker, C, Taherifard, Z, Margolis, DM, Garcia, JV, Chilkoti, A, Murdoch, DM, and Yellen, BB. "Characterizing the Switching Thresholds of Magnetophoretic Transistors." Advanced materials (Deerfield Beach, Fla.) 27, no. 40 (October 2015): 6176-6180.

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Guptill, JT, Juel, VC, Massey, JM, Anderson, AC, Yi, JS, Chopra, M, and Jr, HJF. "EFFECT OF THERAPEUTIC PLASMA EXCHANGE ON IMMUNOGLOBULINS." October 2015.

Scholars@Duke

Hobson-Webb, LD, Guptill, JT, Russo, MA, Anderson, AC, Massey, JM, Gable, K, Juel, VC, Massey, EW, Sanders, DB, and Yi, JS. "T CELL REACTIVITY IN INCLUSION BODY MYOSITIS (IBM)." September 2015.

Scholars@Duke

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