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Erika J Crosby, PhD

Assistant Professor in Surgery
Division: 
Surgical Sciences
Office: Research Drive Msrbi, Box 2606, Durham, NC 27710

Education and Training

  • Ph.D., University of Pennsylvania, 2014
  • B.S., Bucknell University, 2009

Selected Grants

Publications

Crosby, Erika J., Junping Wei, Xiao Yi Yang, Gangjun Lei, Tao Wang, Cong-Xiao Liu, Pankaj Agarwal, et al. “Complimentary mechanisms of dual checkpoint blockade expand unique T-cell repertoires and activate adaptive anti-tumor immunity in triple-negative breast tumors.” Oncoimmunology 7, no. 5 (2018): e1421891. https://doi.org/10.1080/2162402X.2017.1421891.

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Ren, Jun, William R. Gwin, Xinna Zhou, Xiaoli Wang, Hongyan Huang, Ni Jiang, Lei Zhou, et al. “Adaptive T cell responses induced by oncolytic Herpes Simplex Virus-granulocyte macrophage-colony-stimulating factor therapy expanded by dendritic cell and cytokine-induced killer cell adoptive therapy.” Oncoimmunology 6, no. 4 (2017): e1264563. https://doi.org/10.1080/2162402X.2016.1264563.

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Turpin, J., C. Ling, E. J. Crosby, Z. C. Hartman, A. M. Simond, L. A. Chodosh, J. P. Rennhack, et al. “The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment.” Oncogene 35, no. 47 (November 24, 2016): 6053–64. https://doi.org/10.1038/onc.2016.129.

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Gómez, Daniela, Malissa C. Diehl, Erika J. Crosby, Tiffany Weinkopff, and Gudrun F. Debes. “Effector T Cell Egress via Afferent Lymph Modulates Local Tissue Inflammation.” J Immunol 195, no. 8 (October 15, 2015): 3531–36. https://doi.org/10.4049/jimmunol.1500626.

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Crosby, Erika J., Megan Clark, Fernanda O. Novais, E John Wherry, and Phillip Scott. “Lymphocytic Choriomeningitis Virus Expands a Population of NKG2D+CD8+ T Cells That Exacerbates Disease in Mice Coinfected with Leishmania major.” J Immunol 195, no. 7 (October 1, 2015): 3301–10. https://doi.org/10.4049/jimmunol.1500855.

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Schadler, Keri L., Erika J. Crosby, Alice Yao Zhou, Dong Ha Bhang, Lior Braunstein, Kwan Hyuck Baek, Danielle Crawford, et al. “Immunosurveillance by antiangiogenesis: tumor growth arrest by T cell-derived thrombospondin-1.” Cancer Res 74, no. 8 (April 15, 2014): 2171–81. https://doi.org/10.1158/0008-5472.CAN-13-0094.

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Crosby, Erika J., Michael H. Goldschmidt, E John Wherry, and Phillip Scott. “Engagement of NKG2D on bystander memory CD8 T cells promotes increased immunopathology following Leishmania major infection.” Plos Pathog 10, no. 2 (February 2014): e1003970. https://doi.org/10.1371/journal.ppat.1003970.

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Rakhra, K., P. Bachireddy, T. Zabuawala, R. Zeiser, L. Xu, A. Kopelman, A. C. Fan, et al. “CD4+ T Cells Contribute to the Remodeling of the Microenvironment Required for Sustained Tumor Regression upon Oncogene Inactivation.” Cancer Cell 18, no. 6 (December 14, 2010): 696. https://doi.org/10.1016/j.ccr.2010.12.001.

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Rakhra, Kavya, Pavan Bachireddy, Tahera Zabuawala, Robert Zeiser, Liwen Xu, Andrew Kopelman, Alice C. Fan, et al. “CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation.” Cancer Cell 18, no. 5 (November 16, 2010): 485–98. https://doi.org/10.1016/j.ccr.2010.10.002.

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