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Debara Lyn Tucci, MD

Adjunct Professor in the Department of Surgery
Office: 1559 Hosp South, Blue Zone, Durham, NC 27710
Campus Mail: DUMC Box 3805 Med Ctr, Durham, NC 27710

The focus of current research efforts is in defining the effects of conductive hearing impairment on the development and function of the central auditory system. The ultimate goal of this research is to understand the impact of hearing loss, such as that associated with otitis media, on the development of auditory function in children. Experiments are currently being performed in which central auditory system activity is studied using the 2-deoxyglucose method following unilateral neonatal conductive hearing loss. Future experiments will examine changes in cell structure and interneuronal connections following acute and chronic conductive hearing loss in both neonatal and adult animals.

A second research program is focused on issues related to the cochlear implant. The cochlear implant is a device which allows for electrical stimulation of the auditory nerve in profoundly deaf patients. It has previously been demonstrated in animal studies as well as in human tissue histopathology that degeneration of central auditory pathways occurs following severe damage to the inner ear. It has been suggested that the introduction of electrical stimulation via a cochlear implant may prevent or reverse some of these degenerative changes. Experiments conducted previously examined this issue in the neonatally and adult deafened rat. Tissue analysis is currently undergoing completion.

Education and Training

  • M.D., University of Virginia, 1985

Publications

Alberg, Joni, Matthew G. Crowson, and Debara L. Tucci. “Access to and Uptake of Cochlear Implantation Among Children in North Carolina..” N C Med J 77, no. 4 (July 2016): 247–52. https://doi.org/10.18043/ncm.77.4.247.

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Witsell, David L., Tawfiq Khoury, Kristine A. Schulz, Robert Stachler, Debara L. Tucci, and Daniel Wojdyla. “Evaluation of Compliance for Treatment of Sudden Hearing Loss: A CHEER Network Study..” Otolaryngol Head Neck Surg 155, no. 1 (July 2016): 48–55. https://doi.org/10.1177/0194599816650175.

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Piker, Erin G., Kris Schulz, Kourosh Parham, Andrea Vambutas, David Witsell, Debara Tucci, Jennifer J. Shin, et al. “Variation in the Use of Vestibular Diagnostic Testing for Patients Presenting to Otolaryngology Clinics with Dizziness..” Otolaryngol Head Neck Surg 155, no. 1 (July 2016): 42–47. https://doi.org/10.1177/0194599816650173.

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Crowson, Matthew G., Aniruddha Patki, and Debara L. Tucci. “A Systematic Review of Diuretics in the Medical Management of Ménière's Disease..” Otolaryngol Head Neck Surg 154, no. 5 (May 2016): 824–34. https://doi.org/10.1177/0194599816630733.

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Crowson, Matthew G., and Debara L. Tucci. “Mini Review of the Cost-Effectiveness of Unilateral Osseointegrated Implants in Adults: Possibly Cost-Effective for the Correct Indication..” Audiol Neurootol 21, no. 2 (2016): 69–71. https://doi.org/10.1159/000443629.

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Saunders, James E., David M. Barrs, Wenfeng Gong, Blake S. Wilson, Karen Mojica, and Debara L. Tucci. “Cost Effectiveness of Childhood Cochlear Implantation and Deaf Education in Nicaragua: A Disability Adjusted Life Year Model..” Otol Neurotol 36, no. 8 (September 2015): 1349–56. https://doi.org/10.1097/MAO.0000000000000809.

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Emmett, Susan D., Debara L. Tucci, Magteld Smith, Isaac M. Macharia, Serah N. Ndegwa, Doreen Nakku, Kaitesi B. Mukara, et al. “GDP Matters: Cost Effectiveness of Cochlear Implantation and Deaf Education in Sub-Saharan Africa..” Otol Neurotol 36, no. 8 (September 2015): 1357–65. https://doi.org/10.1097/MAO.0000000000000823.

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Patki, Aniruddha, and Debara L. Tucci. “Choice of ear for cochlear implantation: implant the better- or worse-hearing ear?.” Laryngoscope 125, no. 1 (January 2015): 5–6. https://doi.org/10.1002/lary.24736.

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