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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants

Publications

Newell, KA, Asare, A, Kirk, AD, Gisler, T, Suthanthiran, M, Burlingham, W, Marks, W, Turka, L, and Seyfert-Margolis, V. "A unique B cell signature associated with operational tolerance." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Rigby, MR, Trexler, AM, Bello-Labom, H, Kirk, AD, Pearson, TC, Kean, L, and Larsen, CP. "Antagonism of signaling through CD28 or LFA-1, but not CD154, result in abortive activation of antigen-stimulated T cells." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Rigby, MR, Trexler, AM, Bello-Labom, H, Kirk, AD, Pearson, TC, Kean, L, and Larsen, CP. "Antagonism of signaling through CD28 or LFA-1, but not CD154, result in abortive activation of antigen-stimulated T cells." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Ford, ML, Steeds, CM, Wagener, ME, Kirk, AD, and Larsen, CP. "CD8+ memory T cells specific for a single surrogate minor antigen are sufficient to inhibit transplant tolerance induced by CTLA-4 ig and anti-CD154." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Ford, ML, Steeds, CM, Wagener, ME, Kirk, AD, and Larsen, CP. "CD8+ memory T cells specific for a single surrogate minor antigen are sufficient to inhibit transplant tolerance induced by CTLA-4 ig and anti-CD154." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Shen, LY, Agarwal, A, Turgeon, NA, Larsen, CP, Pearson, TC, Bray, RA, Gebel, HM, Kirk, AD, and Kokko, KE. "Combined liver-kidney transplantation across a positive flow crossmatch: A cause for concern?." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Shen, LY, Agarwal, A, Turgeon, NA, Larsen, CP, Pearson, TC, Bray, RA, Gebel, HM, Kirk, AD, and Kokko, KE. "Combined liver-kidney transplantation across a positive flow crossmatch: A cause for concern?." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Charafeddine, AH, Gunay-Aygun, M, Weaver, TA, Maynard, DM, Agarwal, A, Lwakoshi, N, Gahl, WA, and Kirk, AD. "Compartmentalization of platelet derived CD154: Implications for clinical correlation." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Charafeddine, AH, Gunay-Aygun, M, Weaver, TA, Maynard, DM, Agarwal, A, Lwakoshi, N, Gahl, WA, and Kirk, AD. "Compartmentalization of platelet derived CD154: Implications for clinical correlation." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Cravedi, P, Cheng, O, Kirk, AD, Kleiner, D, and Mannon, RB. "Discovering what the eye can't see: Gene expression in baseline biopsies of kidney allografts." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

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