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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants

Publications

Kirk, AD. "Transplantation tolerance: A look at the nonhuman primate literature in the light of modern tolerance theories." Critical Reviews in Immunology 19, no. 5-6 (1999): 349-388.

Scholars@Duke

Armstrong, N, Buckley, P, Oberley, T, Fechner, J, Dong, Y, Hong, X, Kirk, A, Neville, D, and Knechtle, S. "Analysis of primate renal allografts after T-cell depletion with anti-CD3-CRM9." Transplantation 66, no. 1 (July 1998): 5-13.

Full Text

Harlan, DM, and Kirk, AD. "Anti-CD154 therapy to prevent graft rejection." Graft 1 (1998): 63-63. (Academic Article)

Scholars@Duke

Van der Werf, WJ, D'Alessandro, AM, Knechtle, SJ, Pilli, G, Hoffmann, RM, Judd, RH, Odorico, JS, Kirk, AD, Rayhill, SC, Sollinger, HW, and Kalayoglu, M. "Infant pediatric liver transplantation results equal those for older pediatric patients." Journal of pediatric surgery 33, no. 1 (January 1998): 20-23.

Full Text

Kirk, AD, Harlan, DM, Armstrong, NN, Davis, TA, Dong, Y, Gray, GS, Hong, X, Thomas, D, Fechner, JH, and Knechtle, SJ. "CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates." Proceedings of the National Academy of Sciences of the United States of America 94, no. 16 (August 1997): 8789-8794.

Full Text

Jerome, KR, Kirk, AD, Pecher, G, Ferguson, WW, and Finn, OJ. "A survivor of breast cancer with immunity to MUC-1 mucin, and lactational mastitis." Cancer Immunology, Immunotherapy 43, no. 6 (February 1997): 355-360.

Full Text

Kirk, AD, Jacobson, LM, Heisey, DM, Fass, NA, Sollinger, HW, and Pirsch, JD. "Posttransplant diastolic hypertension: Associations with intragraft transforming growth factor-β, endothelin, and renin transcription." Transplantation 64, no. 12 (1997): 1716-1720.

Full Text

Kirk, AD, Heisey, DM, D'Alessandro, AM, Knechtle, SJ, Odorico, JS, Rayhill, SC, Sollinger, HW, and Pirsch, JD. "Clinical hepatitis after transplantation of hepatitis C virus-positive kidneys: HLA-DR3 as a risk factor for the development of posttransplant hepatitis." Transplantation 62, no. 12 (December 1996): 1758-1762.

Full Text

Ibrahim, S, Kirk, AD, and Sanfilippo, F. "Phenotype of infiltrating cells in an ex vivo model of human antiporcine hyperacute cardiac xenograft rejection." Transplantation proceedings 28, no. 2 (April 1996): 777-.

Scholars@Duke

Rayhill, SC, Heimes, M, Kirk, AD, and Sollinger, HW. "Simultaneous pancreas - kidney transplantation: Recent experience at the University of Wisconsin." Experimental and Clinical Endocrinology and Diabetes 104, no. 5 (1996): 353-359.

Scholars@Duke

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