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Allan Douglas Kirk, MD, PhD

David C. Sabiston, Jr. Professor of Surgery
Chair, Department of Surgery
Professor of Surgery
Professor in Pediatrics
Professor in the Department of Immunology
Campus Mail: DUMC 3704, Durham, NC 27710

Costimulation Blockade in Organ Transplantion

Allan D. Kirk, MD, PhD, Department of Surgery Chairman
David C. Sabiston, Jr. Professor of Surgery

Education and Training

  • Fellow, Multi Organ Transplantation, University of Wisconsin at Madison, 1995 - 1997
  • Chief Resident, Surgery, Duke University, 1994 - 1995
  • Senior Resident, Surgery, Duke University, 1992 - 1994
  • Research Fellow, Surgery, Duke University, 1989 - 1992
  • Intern & Junior Resident, Surgery, Duke University, 1987 - 1989
  • Ph.D., Duke University, 1992
  • M.D., Duke University School of Medicine, 1987
  • B.S., Old Dominion University, 1983

Selected Grants

Publications

Ford, ML, Wagener, ME, Hanna, SS, Pearson, TC, Kirk, AD, and Larsen, CP. "A critical precursor frequency of donor-reactive CD4+ T cell help is required for CD8+ T cell-mediated CD28/CD154-independent rejection." Journal of Immunology (Baltimore, Md. : 1950) 180, no. 11 (June 2008): 7203-7211.

Full Text

Rigby, MR, Trexler, A, Bello-Laborn, H, Kean, L, Kirk, AD, Pearson, TC, and Larsen, CP. "Blocking CD28 or LFA-1, but not CD154, signaling results in abortive activation of antigen-stimulated T cells." 67th Annual Meeting of the American-Diabetes-Association. San Francicso, CA. June 6, 2008 - June 10, 2008.: AMER DIABETES ASSOC, June 1, 2008.

Scholars@Duke

Hanna, BV, Gorbach, AM, Gage, FA, Pinto, PA, Silva, JS, Gilfillan, LG, Kirk, AD, and Elster, EA. "Intraoperative assessment of critical biliary structures with visible range/infrared image fusion." Journal of the American College of Surgeons 206, no. 6 (June 2008): 1227-1231.

Full Text

Chamberlain, CE, Penzak, SR, Alfaro, RM, Wesley, R, Daniels, CE, Hale, D, Kirk, AD, and Mannon, RB. "Pharmacokinetics of low and maintenance dose valganciclovir in kidney transplant recipients." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 8, no. 6 (June 2008): 1297-1302.

Full Text

Russell, MC, Cardona, K, Oliva, VL, Turner, AP, Cano, J, Avila, J, Jiang, W, Leopardi, F, Johnson, B, Scott, E, Strobert, E, Pearson, TC, Kirk, AD, and Larsen, CP. "A novel costimulation blockade regimen for engraftment and function of allogeneic islets in diabetic rhesus macaques." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Russell, MC, Cardona, K, Oliva, VL, Turner, AP, Cano, J, Avila, J, Jiang, W, Leopardi, F, Johnson, B, Scott, E, Strobert, E, Pearson, TC, Kirk, AD, and Larsen, CP. "A novel costimulation blockade regimen for engraftment and function of allogeneic islets in diabetic rhesus macaques." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Newell, KA, Asare, A, Kirk, AD, Gisler, T, Suthanthiran, M, Burlingham, W, Marks, W, Turka, L, and Seyfert-Margolis, V. "A unique B cell signature associated with operational tolerance." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Newell, KA, Asare, A, Kirk, AD, Gisler, T, Suthanthiran, M, Burlingham, W, Marks, W, Turka, L, and Seyfert-Margolis, V. "A unique B cell signature associated with operational tolerance." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Rigby, MR, Trexler, AM, Bello-Labom, H, Kirk, AD, Pearson, TC, Kean, L, and Larsen, CP. "Antagonism of signaling through CD28 or LFA-1, but not CD154, result in abortive activation of antigen-stimulated T cells." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

Rigby, MR, Trexler, AM, Bello-Labom, H, Kirk, AD, Pearson, TC, Kean, L, and Larsen, CP. "Antagonism of signaling through CD28 or LFA-1, but not CD154, result in abortive activation of antigen-stimulated T cells." 8th American Transplant Congress. Toronto, CANADA. May 31, 2008 - June 4, 2008.: BLACKWELL PUBLISHING, May 1, 2008.

Scholars@Duke

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