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Alexander Tan Limkakeng Jr., MD, MHS

Director, Acute Care Research
Associate Professor of Surgery
Office: 2301 Erwin Road, Box 3096, Durham, NC 27710
Campus Mail: DUMC 2301 Erwin Road Box 3096, Durham, NC 27710

My personal research interest is finding new ways to diagnose acute coronary syndrome. In particular, I am interested in novel biomarkers and precision medicine approaches to this problem. As Vice Chief of Research for the Duke Division of Emergency Medicine, I also work with researchers from many fields spanning global health, innovation, clinical trials, basic discovery and translational research. The common element is time-sensitive health conditions. I help to oversee a team of research professionals in multicenter emergency department studies funded by the National Institutes of Health, foundations, and industry partners.

Education and Training

  • M.H.S., Duke University, 2012
  • M.D., University of Pennsylvania, 2001

Publications

Gerardo, C. J., E. Silvius, S. Schobel, J. Eppensteiner, L. McGowan, A. T. Limkakeng, A. D. Kirk, and E. A. Elster. “ASSOCIATION OF A CYTOKINE RESPONSE NETWORK WITH FUNCTIONAL RECOVERY FROM SNAKEBITE ENVENOMING.” In Toxicon, 182:S15–16, 2020.

Scholars@Duke

Hertz, Julian T., Francis M. Sakita, Godfrey L. Kweka, Alexander T. Limkakeng, Sophie W. Galson, Jinny J. Ye, Tumsifu G. Tarimo, et al. “Acute myocardial infarction under-diagnosis and mortality in a Tanzanian emergency department: A prospective observational study.” Am Heart J 226 (June 5, 2020): 214–21. https://doi.org/10.1016/j.ahj.2020.05.017.

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Shah, Nidhi, Chen Chen, Nataly Montano, David Cave, Rebecca Siegel, Nina T. Gentile, Alexander T. Limkakeng, Anita B. Kumar, Yan Ma, and Andrew C. Meltzer. “Video capsule endoscopy for upper gastrointestinal hemorrhage in the emergency department: A systematic review and meta-analysis.” Am J Emerg Med 38, no. 6 (June 2020): 1245–52. https://doi.org/10.1016/j.ajem.2020.03.008.

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Fitzgerald, Robert L., Judd E. Hollander, W Frank Peacock, Alexander T. Limkakeng, Nancy Breitenbeck, E Joy Rivers, André Ziegler, Michael Laimighofer, and Christopher deFilippi. “The 99th percentile upper reference limit for the 5th generation cardiac troponin T assay in the United States.” Clin Chim Acta 504 (May 2020): 172–79. https://doi.org/10.1016/j.cca.2020.01.027.

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Christenson, Robert H., Show-Hong Duh, Fred A. Apple, Richard Nowak, W Frank Peacock, A. T. Limkakeng, Zohrab Bostanian, Amin Mohammad, James McCord, and Christopher R. deFilippi. “Pivotal findings for a high-sensitivity cardiac troponin assay: Results of the HIGH-US study.” Clin Biochem 78 (April 2020): 32–39. https://doi.org/10.1016/j.clinbiochem.2019.10.013.

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Kheang, Sopagna, Clarissa G. Rodrigues, Joao Ricardo N. Vissoci, Almujtaba Hassan, Christian Muller, Deborah Muller, and Alexander T. Limkakeng. “Stress-delta B-type Natriuretic Peptide Levels as a Test for Inducible Myocardial Ischemia: A Systematic Review and Meta-Analysis.” Cureus 12, no. 3 (March 2, 2020): e7165. https://doi.org/10.7759/cureus.7165.

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Hertz, Julian T., Godfrey L. Kweka, Gerald S. Bloomfield, Alexander T. Limkakeng, Zak Loring, Gloria Temu, Blandina T. Mmbaga, Charles J. Gerardo, and Francis M. Sakita. “Patterns of Emergency Care for Possible Acute Coronary Syndrome Among Patients with Chest Pain or Shortness of Breath at a Tanzanian Referral Hospital.” Glob Heart 15, no. 1 (February 6, 2020): 9. https://doi.org/10.5334/gh.402.

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Theophanous, Rebecca G., Alexander T. Limkakeng, and Joshua S. Broder. “Duplicated or Ectopic Renal Collecting System in Two Adult Emergency Department Patients.” J Emerg Med 58, no. 2 (February 2020): e59–61. https://doi.org/10.1016/j.jemermed.2019.10.014.

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Hertz, Julian T., Francis M. Sakita, Alexander T. Limkakeng, Blandina T. Mmbaga, Lambert T. Appiah, John A. Bartlett, and Sophie W. Galson. “The burden of acute coronary syndrome, heart failure, and stroke among emergency department admissions in Tanzania: A retrospective observational study.” Afr J Emerg Med 9, no. 4 (December 2019): 180–84. https://doi.org/10.1016/j.afjem.2019.07.001.

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