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Nizar Abdelfattah, MD

House Staff
College/University: 
University of Alexandria, Egypt
Medical School: 
University of Alexandria, Egypt

Clinical and Research Interests

I lead several studies related to retinal imaging research. My main interests include etiologic and pathogenic factors contributing to chronic eye diseases, quantifying risk factors of macular diseases, and applications of artificial intelligence in retinal imaging. I have also been working for years towards global ophthalmology services and online medical education.

Honors and Awards

  1. Outstanding Reviewer Award.
    Selected by ASCRS and ESCRS foundations among top 10 reviewers every year on basis of scholarly achievements, editorial services, and contribution to the quality of cataract and refractive surgery publications. December 2017.
  2. Physician with Exceptional Ability Award.
    Selected by international experts in ophthalmology on basis of “academic achievement, exceptional medical and research abilities significantly above that ordinarily encountered in the United States”. Thereby awarded Permanent Residence of the United States. October 2017.
  3. Golden Key International Honour Society.
    Elected by peers & faculty to join a society that includes students demonstrating integrity, clinical excellence (top 15%), altruism and empathy in patients’ care. February 2017.
  4. Sigma Xi Society.
    Election for The Scientific Research Honor Society, February 2017.
  5. National Eye Institute Travel Award.
    Fourth Biennial International Symposium on AMD, Harvard Medical School. September 2016
  6. Article-of-the-Year Award.
    Paper Title: Prospective Trial of Treat-and-Extend versus Monthly Dosing for Neovascular Age-Related Macular Degeneration. American Academy of Ophthalmology. February 2016
  7. Best Research Award: University of Texas Medical Branch.
    Paper Title: Progression and Risk Factors of Macular Atrophy in Patients with Neovascular Age Related Macular Degeneration Undergoing Anti-VEGF Therapy. February 2016
  8. MIT Outstanding Poster Award Nomination: ARVO Foundation.
    Paper Title: Characterization of Best’s Vitelliform Macular Dystrophy (BVMD) on Multimodal Imaging. May 2016
  9. ARVO Foundation Travel Grant Award.
    Paper Title: Characterization of Best’s Vitelliform Macular Dystrophy (BVMD) on Multimodal Imaging. May 2016
  10. UTMB Travel Award: University of Texas.
    Paper Title: Progression and Risk Factors of Macular Atrophy in Patients with Neovascular Age Related Macular Degeneration Undergoing Anti-VEGF Therapy. February 2016
  11. Highlights of Corneal Research Award.
    Paper Title: Noninvasive Imaging of Tear Film Dynamics in Eyes with Ocular Surface Disease. World Cornea Congress / ASCRS Foundation. April 2015.
  12. Best Poster Award.
    Paper: Independent Validation and Verification of Keratograph for Measuring Tear Meniscus Height in Ocular Surface Disease Patients. American Society of Cataract and Refractive Surgery. April 2015.
  13. Best Paper Award.
    Paper Title: Use of Corneal Topography to Assess Tear Film and Meibography in Ocular Surface Diseases. American Society of Cataract and Refractive Surgery. April 2015
  14. AMTAR Travel Award.
    Paper Title: “Evaluation of Corneal Changes following Intracorneal Ring Segments Implantation in Cases of Keratoconus Using Femtosecond Laser”. Association for American Medical Training and Research. April 2013
  15. Upper First Class Honors.
    Graduated with Honors with Class of 2012. University of Alexandria. February 2012.
  16. Women and Children’s Hospital Humanism Award.
    For raising funds to establish a charity “Blood Bank”. December 2009.
  17. Women and Children’s Hospital Humanism Award.
    For raising funds to establish a charity “Renal Dialysis” unit. May 2007.

Grants

  1. “An Automated Method to Detect and Analyze Atrophic Lesions in AMD”
    Role in Project: Clinical Research Fellow
    Amount: $ 160,000
    Source: Bright Focus Foundation Funding Grant (#M2016088)
    Type: Research Grant │ Jul ‘16 – Jun ‘18
  2. “Analysis of the Macular Atrophy in the HARBOR Trial Using Multimodal Imaging Systems”
    Role in Project: Sub-Investigator (Project Lead)
    Amount: $ 850,000
    Source: Genentech Inc. Foundation Sponsored National Merit Scholarship
    Type: Research Grant │ Jan ‘16 – Jun ‘17
  3. “Ocular Aberrations and Contrast Sensitivity following Wavefront Excimer Laser Treatments”
    Role in Project: Principal Investigator
    Amount: $5,000
    Source: ASCRS Foundation Research Scholarship
    Type: Research Grant │ Apr ’15 – Sep ‘15
  4. “Noninvasive Imaging of Tear Film Dynamics in Eyes with Ocular Surface Diseases”
    Role in Project: Clinical Research Fellow
    Amount: $35,000
    Source: Allergan Pharmaceuticals
    Type: Research Funding │ Aug ’13 – May ‘14

Conference Presentations

  1. Abdelfattah NS, Sadda SR, Wykoff CC. Macular Atrophy in NVAMD with Monthly versus Treat-and-Extend Ranibizumab: Findings from the TREX-AMD Randomized Trial. American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 2017; Los Angeles, CA.
  2. Charles Wykoff, Croft D, Brown D, Ou W, Payne J, Abdelfattah NS, Sadda SR. Treat-and Extend versus Monthly Ranibizumab: Second Year Results of the TREX-AMD Trial. American Academy of Ophthalmology (AAO) Annual Meeting; October 2016; Chicago, IL.
  3. Abdelfattah NS, Al-Sheikh M, Pitetta S, Wang R, Sadda SR, Wykoff C. Macular Atrophy in Neovascular Age-Related Macular Degeneration Eyes Treated with Monthly or Treat-and-Extend Ranibizumab: TREX-AMD Report No. 2. American Society of Retina Specialists (ASRS) Annual Meeting; August 2016; San Francisco, CA.
  4. Yousif MO, Abdelfattah NS. Ocular Aberrations and Contrast Sensitivity following Different Wavefront Excimer Laser Treatments. American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 2016; New Orleans, LO.
  5. Abdelfattah NS, Zhang H, Boyer DS, Sadda SR. Macular Atrophy in Patients with Neovascular Age Related Macular Degeneration Undergoing Anti-VEGF Therapy. Paper presented at: Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting; May 2015; Denver, CO.
  6. Abdelfattah NS, Dastiridou A, Sadda SR, Lee OL. Use of Corneal Topography to Assess Tear Film and Meibography in Ocular Surface Disease. American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; April 2015; San Diego, CA.
  7. Abdelfattah NS, Sadda SR, Lee OL. Noninvasive Imaging of Tear Film Dynamics in Eyes with Ocular Surface Disease. World Cornea Congress (WCC); April 2015; San Diego, CA.
  8. Yousif MO, Abdelfattah NS, Zayed AA. Effect of Suction Duration on LASIK Flap Thickness and Hinge Length Using SBK Microkeratome in Flat and Steep Corneas. American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; April 2015; San Diego, CA.
  9. Abdelfattah NS, Alnahrawy OM. Evaluation of Corneal Changes after Intra-Corneal Ring Segments Implantation in Cases of Keratoconus Using Femtosecond Laser. American Society of Cataract and Refractive Surgery and American Society of Ophthalmic Administrators (ASCRS/ASOA) Annual Meeting; April 2013; San Francisco, CA
  10. Abdelfattah NS, Sadda J, Wang Z, Hu Z, Sadda SR. Geographic Atrophy Measurements in Fundus Autofluorescence versus Infrared Reflectance Imaging in Dry Age-related Macular Degeneration. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting; May 2018; Honolulu, HI.
  11. Hu Z, Wang Z, Abdelfattah NS, Sadda J, Sadda SR. Automated Geographic Atrophy Segmentation in Infrared Reflectance Images Using Deep Convolutional Neural Networks. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting; May 2018; Honolulu, HI.
  12. Sadda J, Abdelfattah NS, Wang Z, Hu Z, Sadda SR. Inter-Grader Repeatability of Geographic Atrophy Measurements from Infrared Reflectance Images. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting; May 2018; Honolulu, HI.
  13. Abdelfattah NS, Hariri AH, Al-Sheikh M, Pitetta S, Sadda SR, Wykoff CC. Topographic Analysis of Choroidal Neovascularization and Macular Atrophy in Neovascular Age-related Macular Degeneration: Findings from TREX-AMD Trial. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting; May 2017; Baltimore, MD.
  14. Uji A, Abdelfattah NS, Boyer DS, Balasubramanian S, Lei J, Sadda SR. Variability of Retinal Thickness Measurements in Tilted or Stretched Optical Coherence Tomography Images. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting; May 2017; Baltimore, MD.
  15. Ibrahim MA, Wolfson Y, Munoz B, Strauss RW, West S, Velaga SB, Abdelfattah NS, Huang J, Sadda SR, Birch D, Zrenner E, Scholl HP. Progression of Stargardt Disease as Measured by Spectral Domain Optical Coherence Tomography in the ProgStar Study. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting; May 2017; Baltimore, MD.
  16. Abdelfattah NS. Multimodal Imaging Findings in Vitamin-A Deficiency Retinopathy. American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 2017; Los Angeles, CA.
  17. Abdelfattah NS. Comparison between the State of Ophthalmology Resident Training in the U.S. with International Standards. American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 2016; New Orleans, LO.
  18. Abdelfattah NS, Boyer DS, Sadda SR. Characterization of Best’s Vitelliform Macular Dystrophy (BVMD) on Multimodal Imaging. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting; May 2016; Seattle, WA.
  19. Zhang H, Abdelfattah NS, Boyer DS, Sadda SR. Longitudinal Quantitative OCT Analysis of Drusen in the Fellow Eye of Patients with Unilateral Neovascular Age-Related Macular Degeneration. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting; May 2015; Denver, CO.
  20. Abdelfattah NS, Sadda SR, Lee OL. Independent Validation and Verification of Oculus Keratograph for Measuring Tear Meniscus Height in Ocular Surface Disease Patients. American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; April 2015; San Diego, CA.
  21. Abdelfattah NS, Sadda SR, Lee OL. Noninvasive Keratograph Tear Break-up Time Versus Invasive Fluorescein-Associated Tear Stability Test: Experimental Validation Study. World Cornea Congress (WCC) Meeting; April 2015; San Diego, CA.
  22. Abdelfattah NS, Israel M, Osman N, Zayed AA, Yousif MO. Visual and Topographic Outcomes of Intracorneal Rings after Primary Keratoconus and Post-LASIK Ectasia. World Cornea Congress (WCC) Meeting; April 2015; San Diego, CA.
  23. Abdelfattah NS, Salama AA, Abdel-Baqy MA, et al. Development of an Arabic version of the National Eye Institute Visual Function Questionnaire as a tool to study eye diseases patients in Egypt. Poster session presented at: Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting; May 2013; Seattle, WA.
  24. Abdelfattah NS. Passive Smoking Exposure and Its Indicators to Strategies of Prevention and Control. Poster session presented at: Public Health Department 38th Annular Convention; May 2008; Public Health Department, University of Alexandria, Egypt.

Publications

Wykoff, Charles C., William C. Ou, Daniel E. Croft, John F. Payne, David M. Brown, W Lloyd Clark, Nizar Saleh Abdelfattah, SriniVas R. Sadda, and SriniVas R. TREX-AMD Study Group. “Neovascular age-related macular degeneration management in the third year: final results from the TREX-AMD randomised trial.” The British Journal of Ophthalmology 102, no. 4 (April 2018): 460–64. https://doi.org/10.1136/bjophthalmol-2017-310822.

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Fan, Wenying, Nizar Saleh Abdelfattah, Akihito Uji, Jianqin Lei, Michael Ip, SriniVas R. Sadda, Charles C. Wykoff, and Charles C. TREX-AMD Study Group. “Subfoveal choroidal thickness predicts macular atrophy in age-related macular degeneration: results from the TREX-AMD trial.” Graefe’S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie 256, no. 3 (March 2018): 511–18. https://doi.org/10.1007/s00417-017-3888-2.

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Borrelli, Enrico, Nizar Saleh Abdelfattah, Akihito Uji, Muneeswar Gupta Nittala, David S. Boyer, and SriniVas R. Sadda. “Postreceptor Neuronal Loss in Intermediate Age-related Macular Degeneration.” American Journal of Ophthalmology 181 (September 2017): 1–11. https://doi.org/10.1016/j.ajo.2017.06.005.

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Lei, Jianqin, Siva Balasubramanian, Nizar Saleh Abdelfattah, Muneeswar G. Nittala, and SriniVas R. Sadda. “Proposal of a simple optical coherence tomography-based scoring system for progression of age-related macular degeneration.” Graefe’S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie 255, no. 8 (August 2017): 1551–58. https://doi.org/10.1007/s00417-017-3693-y.

Full Text

Wykoff, Charles C., William C. Ou, David M. Brown, Daniel E. Croft, Rui Wang, John F. Payne, W Lloyd Clark, Nizar Saleh Abdelfattah, SriniVas R. Sadda, and SriniVas R. TREX-AMD Study Group. “Randomized Trial of Treat-and-Extend versus Monthly Dosing for Neovascular Age-Related Macular Degeneration: 2-Year Results of the TREX-AMD Study.” In Ophthalmology. Retina, 1:314–21, 2017. https://doi.org/10.1016/j.oret.2016.12.004.

Full Text

Ibrahim, Mohamed A., Yulia Wolfson, Beatriz Munoz, Rupert Wolfgang Strauss, Sheila West, Swetha Velaga, Nizar Saleh Abdelfattah, et al. “Progression of Stargardt disease as measured by spectral-domain optical coherence tomography (SD-OCT) in the ProgStar Study.” In Investigative Ophthalmology & Visual Science, Vol. 58, 2017.

Scholars@Duke

Abdelfattah, Nizar Saleh, Amir H. Hariri, Mayss Al-Sheikh, Sean Pitetta, Adel Ebraheem, Srinivas R. Sadda, and Charles Clifton Wykoff. “Topographic Analysis of Choroidal Neovascularization (CNV) and Macular Atrophy (MA) in Neovascular Age-related Macular Degeneration (NVAMD): Findings from TREX-AMD Trial.” In Investigative Ophthalmology & Visual Science, Vol. 58, 2017.

Scholars@Duke

Uji, Akihito, Nizar Saleh Abdelfattah, David S. Boyer, Siva Balasubramanian, Jianqin Lei, and SriniVas R. Sadda. “Variability of Retinal Thickness Measurements in Tilted or Stretched Optical Coherence Tomography Images.” Translational Vision Science & Technology 6, no. 2 (March 2017): 1. https://doi.org/10.1167/tvst.6.2.1.

Full Text

Abdelfattah, Nizar S., Mayss Al-Sheikh, Sean Pitetta, Ahmed Mousa, SriniVas R. Sadda, Charles C. Wykoff, and Charles C. Treat-and-Extend Age-Related Macular Degeneration Study Group. “Macular Atrophy in Neovascular Age-Related Macular Degeneration with Monthly versus Treat-and-Extend Ranibizumab: Findings from the TREX-AMD Trial.” Ophthalmology 124, no. 2 (February 2017): 215–23. https://doi.org/10.1016/j.ophtha.2016.10.002.

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Abdelfattah, Nizar Saleh, Hongyang Zhang, David S. Boyer, and SriniVas R. Sadda. “PROGRESSION OF MACULAR ATROPHY IN PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION UNDERGOING ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY.” Retina (Philadelphia, Pa.) 36, no. 10 (October 2016): 1843–50. https://doi.org/10.1097/iae.0000000000001059.

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