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Brian Ezekian, MD

House Staff
Start Year: 
Pennsylvania State University (Schreyer Honors College)
Medical School: 
University of Virginia School of Medicine

Clinical and Research Interests

Strategies for desensitization to overcome the HLA barrier to kidney transplantation; antibody-mediated rejection; novel immunosuppressive strategies

What were you looking for in a residency program?

I was looking for a collegial program with a family feel that provided a balanced focus on technical skills, research, and medical education.

What do you like best about living in Durham and the Triangle?

Great people, food, beer, weather, and natural beauty. The Triangle has all the amenities and activities of a large city, but at an affordable price and with a small town vibe.

What do you like to do outside of Duke?

Spending time with my wife and pets, running, hiking, stand-up paddleboarding, cooking

Honors and Awards

  • American Board of Surgery In-Training Examination Award, 2015-2020
  • Apple Seed Resident Teaching Award, 2018-2019
  • Rosenkrantz Award Presentation, 2018
  • American Transplant Congress Young Investigator Award, 2018
  • Alpha Omega Alpha Honor Medical Society Inductee, 2017
  • Federation of Clinical Immunology Societies Travel Grant, 2017


Ezekian, Brian, Brian Englum, Brian F. Gilmore, Uttara P. Nag, Jina Kim, Harold J. Leraas, Jonathan C. Routh, Henry E. Rice, and Elisabeth T. Tracy. “Renal medullary carcinoma: A national analysis of 159 patients.” Pediatr Blood Cancer 64, no. 11 (November 2017).

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Gulack, Brian C., Harold J. Leraas, Brian Ezekian, Jina Kim, Christopher Reed, Obinna O. Adibe, Henry E. Rice, and Elisabeth T. Tracy. “Outcomes following elective resection of congenital pulmonary airway malformations are equivalent after 3 months of age and a weight of 5 kg.” J Pediatr Surg, October 9, 2017.

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Ezekian, Brian, Brian R. Englum, Brian F. Gilmore, Jina Kim, Harold J. Leraas, Timothy A. Driscoll, Elisabeth T. Tracy, and Henry E. Rice. “Children Receiving Hematopoietic Stem Cell Transplantation are at Increased Risk of Onychocryptosis Requiring Surgical Management.” J Pediatr Hematol Oncol 39, no. 7 (October 2017): e353–56.

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Leraas, Harold J., Jina Kim, Uttara Nag, Brian Ezekian, Brian C. Gulack, Christopher R. Reed, Henry E. Rice, and Elisabeth T. Tracy. “Thoracoscopic Approach Provides a Safe Alternative to Open Surgery in Elective Cases for Newborns.” In Journal of the American College of Surgeons, 225:e140–41. Elsevier BV, 2017.

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Ezekian, Brian, Michael S. Mulvihill, Kyle Freischlag, Babatunde A. Yerokun, Robert P. Davis, Matthew G. Hartwig, Stuart J. Knechtle, and Andrew S. Barbas. “Elevated HbA1c in donor organs from patients without a diagnosis of diabetes portends worse liver allograft survival.” Clin Transplant 31, no. 9 (September 2017).

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Nag, Uttara P., Harold J. Leraas, Jina Kim, Brian Ezekian, Christopher Reed, Jeffrey H. Lawson, and Elisabeth T. Tracy. “PC178 Age Associated With Mortality and Outcomes in Pediatric Vascular Trauma.” In Journal of Vascular Surgery, 65:187S-188S. Elsevier BV, 2017.

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Lidsky, Michael E., Paul J. Speicher, Brian Ezekian, Edwin W. Holt, Daniel P. Nussbaum, Anthony W. Castleberry, Alexander Perez, and Theodore N. Pappas. “Subtotal cholecystectomy for the hostile gallbladder: failure to control the cystic duct results in significant morbidity.” Hpb (Oxford) 19, no. 6 (June 2017): 547–56.

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Kwun, J., C. Burghuber, M. Manook, B. Ezekian, J. Park, K. Freishlag, J. Yoon, N. Iwakoshi, A. Farris, and S. Knechtle. “Dual Targeting of Costimulation and Proteasome to Desensitize and Prolong Graft Survival of Sensitized Nonhuman Primates.” In American Journal of Transplantation, 17:212–212. WILEY, 2017.


Ezekian, B., J. Kwun, M. Manook, K. Freischlag, V. Curfman, E. Branum, J. Park, J. Yi, S. Jordan, and S. Knechtle. “Dual Targeting with Carfilzomib and Tocilizumab Abrogates Antibody-Mediated Rejection and Prolongs Survival in a Highly Sensitized Rhesus Model of Kidney Transplantation.” In American Journal of Transplantation, 17:211–211. WILEY, 2017.


Kwun, J., B. Ezekian, M. Manook, E. Branum, V. Curfman, J. Park, K. Freishlag, J. Yoon, and S. Knechtle. “Effective Targeting Plasma Cells with Daratumumab (Anti-CD38) and Mozobil (Anti-CXCR4) in a Sensitized Non-Human Primate Model.” In American Journal of Transplantation, 17:211–12. WILEY, 2017.