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Brian Ezekian, MD

House Staff
Start Year: 
Pennsylvania State University (Schreyer Honors College)
Medical School: 
University of Virginia School of Medicine

Clinical and Research Interests

Strategies for desensitization to overcome the HLA barrier to kidney transplantation; antibody-mediated rejection; novel immunosuppressive strategies

What were you looking for in a residency program?

I was looking for a collegial program with a family feel that provided a balanced focus on technical skills, research, and medical education.

What do you like best about living in Durham and the Triangle?

Great people, food, beer, weather, and natural beauty. The Triangle has all the amenities and activities of a large city, but at an affordable price and with a small town vibe.

What do you like to do outside of Duke?

Spending time with my wife and pets, running, hiking, stand-up paddleboarding, cooking

Honors and Awards

  • American Board of Surgery In-Training Examination Award, 2015-2020
  • Apple Seed Resident Teaching Award, 2018-2019
  • Rosenkrantz Award Presentation, 2018
  • American Transplant Congress Young Investigator Award, 2018
  • Alpha Omega Alpha Honor Medical Society Inductee, 2017
  • Federation of Clinical Immunology Societies Travel Grant, 2017


Ezekian, Brian, Paul M. Schroder, Kyle Freischlag, Janghoon Yoon, Jean Kwun, and Stuart J. Knechtle. “Contemporary Strategies and Barriers to Transplantation Tolerance.” Transplantation 102, no. 8 (August 2018): 1213–22.

Full Text

Ezekian, B., J. Kwun, P. Schroder, M. Manook, J. Yoon, M. Mulvihill, K. Freischlag, et al. “Carfilzomib and Belatacept Reduces DSA and Prolongs Survival in a Highly Sensitized Rhesus Model of Kidney Transplantation.” In American Journal of Transplantation, 18:246–246. WILEY, 2018.


Ezekian, B., J. Kwun, M. Manook, P. Schroder, J. Yoon, M. Mulvihill, K. Freischlag, et al. “Combination Proteasome Inhibition and Anti-BAFF Therapy Permits Highly Sensitized Rhesus Kidney Transplantation.” In American Journal of Transplantation, 18:309–10. WILEY, 2018.


Schroder, P., B. Ezekian, F. Saccoccio, J. Yoon, M. Dennis, K. Freischlag, J. Kwun, S. Permar, and S. Knechtle. “Humoral Immunity to CMV Remains Intact after Dual Targeting Desensitization in Allosensitized Nonhuman Primates.” In American Journal of Transplantation, 18:899–900. WILEY, 2018.


Freischlag, K., P. Shroder, B. Ezekian, M. Mulvihill, and S. Knechtle. “Implementation of the Lung Allocation Score is Associated with Decreased Mortality in Combined Liver-Lung Allograft Recipients.” In American Journal of Transplantation, 18:861–861. WILEY, 2018.


Scheuermann, U., K. Freischlag, Q. Gao, J. Yerxa, B. Ezekian, R. Davis, P. Schroder, and A. Barbas. “Kidney Donor Profile Index (KDPI) is Not Inferior to Liver Donor Risk Index (LDRI) in Predicting Long-Term Liver Graft Survival.” In American Journal of Transplantation, 18:578–578. WILEY, 2018.


Freischlag, K., B. Ezekian, P. Schroder, J. Everitt, J. Yoon, M. Swiderska-Syn, W. Parker, A. Diehl, J. Kwun, and S. Knechtle. “Long-Term HIF-1 alpha Stabilization is Associated with Fibrosis in Rat Lung Allografts.” In American Journal of Transplantation, 18:490–91. WILEY, 2018.


Leraas, Harold J., Laura H. Rosenberger, Yi Ren, Brian Ezekian, Uttara P. Nag, Christopher R. Reed, Samantha M. Thomas, Eun-Sil Shelley Hwang, and Elisabeth T. Tracy. “Pediatric phyllodes tumors: A review of the National Cancer Data Base and adherence to NCCN guidelines for phyllodes tumor treatment.” J Pediatr Surg 53, no. 6 (June 2018): 1123–28.

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Yoon, J., B. Ezekian, M. Manook, J. Kwun, and S. Knechtle. “Rhesus Monkey Have natural Antibody toward Swine That is Not Influenced by Allosensitization nor by Carfilzomib/tocilizumab.” In American Journal of Transplantation, 18:764–764. WILEY, 2018.


Mulvihill, M., B. Ezekian, Q. Gao, K. Samy, R. Davis, F. Leopardi, A. Belli, et al. “Rhesus-Specific Anti-Thymocyte Globulin as an Adjuvant to Costimulatory-Blockade-Based Immunotherapy.” In American Journal of Transplantation, 18:899–899. WILEY, 2018.